- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Heart Failure Treatment and Management
- Cardiac Structural Anomalies and Repair
- Cardiac electrophysiology and arrhythmias
- Transplantation: Methods and Outcomes
- Cardiovascular Function and Risk Factors
- Cardiomyopathy and Myosin Studies
- Acute Myocardial Infarction Research
- Cardiac Ischemia and Reperfusion
- Pulmonary Hypertension Research and Treatments
- Receptor Mechanisms and Signaling
- Pharmacological Effects and Assays
- Nitric Oxide and Endothelin Effects
- Cardiovascular Issues in Pregnancy
- Cardiac pacing and defibrillation studies
- Cardiac Imaging and Diagnostics
- Neuropeptides and Animal Physiology
- Neurological Complications and Syndromes
- Mitochondrial Function and Pathology
- Lipoproteins and Cardiovascular Health
- Noise Effects and Management
- Adipose Tissue and Metabolism
- Viral Infections and Immunology Research
- Trypanosoma species research and implications
Asklepios Klinik Langen
2008-2023
Deakin University
2017
Bridgepoint (United Kingdom)
2013
Krankenhaus St. Elisabeth und St. Barbara
2000-2006
Goethe University Frankfurt
1986-1999
University Hospital Frankfurt
1992
Technical University of Munich
1990
In current international guidelines, intraaortic balloon counterpulsation is considered to be a class I treatment for cardiogenic shock complicating acute myocardial infarction. However, evidence based mainly on registry data, and there paucity of randomized clinical trials.
This study examined the effects of sacubitril/valsartan on N-terminal pro–B-type natriuretic peptide (NT-proBNP) levels and determined patient characteristics associated with favorable NT-proBNP reduction response. reflect cardiac wall stress predict event risk in patients acute decompensated heart failure (ADHF). Post-hoc analysis TRANSITION (Comparison Pre- Post-discharge Initiation Sacubitril/Valsartan Therapy HFrEF Patients After an Acute Decompensation Event) study, including stabilized...
In several population based cohort studies associations between aircraft noise and various diagnoses of cardiovascular disease were observed. However, no study has yet addressed the risk recurrences in relation to transportation patients with acute coronary heart disease. We conducted a prospective patient 737 individuals recruited from eleven cardiac centers Rhine-Main region vicinity Frankfurt Airport. All had an angiographically confirmed syndrome diagnosed July 2013 November 2018....
Objectives: The prospective Balanced Evaluation of Atrial Tachyarrhythmias in Stimulated patients (BEATS) study compared atrial tachyarrhythmia (AT) detection by means serial ECG recordings versus device detection. Background: annual incidence AT with dual‐chamber pacemakers may be significantly underestimated based on and Holter recordings. Methods: A DDD(R) capable AT‐triggered dual‐channel electrogram (EGM) storage was implanted 254 (70 ± 11 years, 159 men) a class I pacing indication....
Aims:The aim of this post hoc subgroup analysis the Intraaortic Balloon Pump in Cardiogenic Shock II trial was to compare clinical outcome patients treated with either clopidogrel or newer, more potent P2Y 12 receptor inhibitors prasugrel ticagrelor. Methods and results:The primary endpoint one-year mortality respect different inhibitors.Secondary safety endpoints were GUSTO bleedings until hospital discharge.After exclusion 117 (patients who died before during PCI, unavailable information...
Cardiomyopathic hamsters develop heart disease early in life, which leads to congestive failure and death as these age. Hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitors have been reported reduce ubiquinone concentrations deteriorate myocardial function humans experimental animals. HMG-CoA differ regarding their ability penetrate extrahepatic tissues. As a consequence, lovastatin inhibits cholesterol biosynthesis at least 100-fold more effectively than pravastatin cells. We...
SCHERER, M., et al. : Extension of Generator Longevity by Use High Impedance Ventricular Leads. The resistance a pacing lead negatively correlates to current consumption. A prospective, randomized trial was conducted evaluate the effect high impedance ventricular (CapSure Z) on generator longevity compared conventional SP) eighty‐nine patients were included in study ( 51 male, 37 female, age 70.0 ± 10.3 years ). Forty‐six received CapSure SP (5024 bipolar), and 43 Z (5034 bipolar) fashion....
In several population based cohort studies associations between aircraft noise and various diagnoses of cardiovascular disease were observed. However, no study has yet addressed the risk recurrences in relation to transportation patients with acute coronary heart disease.We conducted a prospective patient 737 individuals recruited from eleven cardiac centers Rhine-Main region vicinity Frankfurt Airport. All had an angiographically confirmed syndrome diagnosed July 2013 November 2018....