A5028204096- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Organ Donation and Transplantation
- Hepatocellular Carcinoma Treatment and Prognosis
- Renal Transplantation Outcomes and Treatments
- Transplantation: Methods and Outcomes
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Pediatric Hepatobiliary Diseases and Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Congenital Anomalies and Fetal Surgery
- Liver Diseases and Immunity
- Gallbladder and Bile Duct Disorders
- Neurological Complications and Syndromes
- Metabolism and Genetic Disorders
- Hepatitis Viruses Studies and Epidemiology
- Drug-Induced Hepatotoxicity and Protection
- Cytomegalovirus and herpesvirus research
- Hemoglobinopathies and Related Disorders
- Viral-associated cancers and disorders
- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Tuberculosis Research and Epidemiology
- Vascular anomalies and interventions
Istanbul Florence Nightingale Hospital
2012-2025
Acıbadem Adana Hospital
2022-2024
Acıbadem University
2022-2024
National University Health System
2023
Tan Tock Seng Hospital
2023
Al-Azhar University
2023
University of Cagliari
2023
Kent Hastanesi
2022-2023
Zagazig University
2023
Univerzitetski Klinički Centar Srbije
2023
<h3>Background & Aims</h3> Little is known about outcomes of liver transplantation for patients with non-alcoholic steatohepatitis (NASH). We aimed to determine the frequency and NASH in Europe identify prognostic factors. <h3>Methods</h3> analysed data from transplanted end-stage disease between January 2002 December 2016 using European Liver Transplant Registry database. compared versus other aetiologies. The principle endpoints were patient overall allograft survival. <h3>Results</h3>...
Abstract Nonalcoholic steatohepatitis (NASH)-related cirrhosis has become one of the most common indications for liver transplantation (LT), particularly in candidates older than 65 years. Typically, NASH have concurrent obesity, metabolic, and cardiovascular risks, which directly impact patient evaluation selection, waitlist morbidity mortality, eventually posttransplant outcomes. The purpose these guidelines is to highlight specific features commonly observed strategies optimize...
Living donor liver transplantation is now a common practice in countries which the availability of cadaveric organs limited. The preoperative preparation, intraoperative surgical technique, and postoperative care donors recipients have evolved recent years. We retrospectively compared 67 with remnant volume equal to or more than 30% (group 1) 14 who had less 2) for outcomes. All complications were systematically classified. Donors showed significantly higher peak aspartate aminotransferase,...
A large database of 1773 HCC patients in Turkey was examined. 41.9% had alpha-fetoprotein (AFP) levels <20 IU/ml and an additional 16.123% values between 20-100 IU/ml. This 58% the cohort (<100 AFP levels) examined detail. 66% with small (<5 cm) HCCs low AFP, compared to 49% larger (>5 HCCs. The mean diameter (MTD) MTD, tumors 8.4cm. Therefore, factors other than must contribute tumor growth. Larger both higher platelet increased PVT percent. Linear regression analysis for MTD multifocality...
The impact of donor arterial variations and their management was investigated retrospectively in 527 consecutive allografts. Anomalous arteries were found 161 grafts (30.6 per cent). There no significant difference the overall incidence complications between with normal (3.6 cent) abnormal (5.6 anatomy. However, there a higher transplants requiring multiple anastomoses (P = 0.02), or anastomosis vessels to recipient aorta 0.0003) without 0.04) an interposition graft for reconstruction....
An accepted definition of donor exclusion criteria has not been established for living liver transplantation (LDLT). The use elderly donors to expand the pool raises ethical concerns about safety. aims this study were (1) comparison postoperative outcomes by age (≥ 50 versus < years) and (2) evaluation impact extent right hepatectomy on outcomes. group included 150 who underwent between October 2004 April 2009. Extended surgery (ECS) was defined as with middle hepatic vein (MHV) harvesting...
The graft-to-recipient weight ratio (GRWR) is an important selection criterion for living donor liver transplantation (LDLT). generally accepted threshold known to be 0.8%. We believe that this can reduced under certain conditions. aim of study was evaluate the results these patients with GRWR < Between 2004 and 2015, 649 underwent right lobe LDLT end-stage disease in adult patients. All recipients who had 0.8% were identified. data retrospectively analyzed compared ≥ There 43 Out patients,...
Tuberculosis is an important cause of morbidity and mortality in renal transplant recipients, but there are insufficient data regarding the efficacy complications therapy INH prophylaxis.This study a retrospective review records 880 recipients two centers Turkey.Tuberculosis developed 36 patients (4.1%) at posttransplant 3-111 months, which 28 were successfully treated. Eight (22.2%) died tuberculosis or anti-tuberculosis therapy. Use rifampin necessitated mean 2-fold increase cyclosporine...
Fulminant hepatic failure is a rare and devastating event during childhood. The etiology of liver reported to change according age geographical location. We aimed investigate, retrospectively, causes outcome fulminant in Turkish children. Thirty-four children with were analysed by means outcome. Etiological factor, clinical presentation, encephalopathy stage biochemical parameters correlated Acute viral hepatitis was detected 12 cases (35.2 per cent) A the most commonly cause among (n = 9,...
Hepatocellular carcinoma (HCC) is the fifth most common fatal cancer and an important healthcare problem worldwide. There are many studies describing prognostic predictive effects of epidermal growth factor receptor 2 (c-erb-B2) 1 (EGFR), transmembrane tyrosine kinases that influence cell proliferation in tumors.The current study aimed to investigate expression levels c-erb-B2, EGFR, PTEN, mTOR, PI3K, p27, ERCC1 hepatocellular their correlation with other clinicopathologic features.Fifty HCC...
In Brief Introduction Previous published studies have shown that age is not a contraindication for deceased donor liver transplantation. The data about elderly recipient after living transplantation (LDLT) unsatisfactory. aim of this study was to evaluate the outcome LDLT with recipients aged 70 years or older. Patients and Methods Between 2005 2013, 469 patients underwent LDLTs. clinical characteristics, preoperative, intraoperative, postoperative data, graft, patients' survival these were...
Several markers of systemic inflammation, including blood C-reactive protein, platelet lymphocyte ratio (PLR) and neutrophil (NLR) have been identified as independent prognosticators for hepatocellular carcinoma (HCC).To attempt to understand the significance these markers, they were examined in relation 4 tumour parameters, namely maximum diameter (MTD), multifocality, portal vein thrombosis (PVT) alpha-fetoprotein (AFP) levels.Using linear logistic regression models, we found that protein...
When a partial liver graft is unable to meet the demands of recipient, clinical phenomenon, small-for-size syndrome (SFSS), may ensue. Clear definition, diagnosis, and management are needed optimize transplant outcomes.A Consensus Scientific committee (106 members from 21 countries) performed an extensive literature review on specific aspects SFSS, recommendations underwent blinded by independent panel, discussion/voting occurred at Conference.The ideal graft-to-recipient weight ratio ≥0.8%...
Abstract: Hepatocellular carcinoma (HCC) is primarily observed in the older children and most cases it develops association with liver cirrhosis. Liver transplantation offers a good chance for long‐term cure. To evaluate outcome of HCC impact living‐donor orthotopic (OLT) on survival retrospective review radiographic, laboratory, pathologic, therapeutic data 13 (six female seven male) chronic disease accompanied were studied. The patients divided into two groups according to modality:...