A5102789473- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Chronic Lymphocytic Leukemia Research
- Microtubule and mitosis dynamics
- Acute Lymphoblastic Leukemia research
- Circular RNAs in diseases
- Cancer, Hypoxia, and Metabolism
- RNA Research and Splicing
- Ubiquitin and proteasome pathways
- Cancer Research and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Antifungal resistance and susceptibility
- Plant-Microbe Interactions and Immunity
- Cell Adhesion Molecules Research
- Plant Pathogens and Fungal Diseases
- Neuroendocrine Tumor Research Advances
Universidade de São Paulo
2016-2021
Clinics Hospital of Ribeirão Preto
2016-2021
Bioénergétique et Ingénierie des Protéines
2017
Candida species are some of the most common causes fungal infection worldwide. The limited efficacy clinically available antifungals warrants search for new compounds treating candidiasis. This study evaluated effect condensed tannin-rich fraction (F2 fraction) Stryphnodendron adstringens on in vitro and vivo growth tropicalis, yeast adhesion properties. F2 exhibited a fungistatic with minimum inhibitory concentration ranging from 0.5 to 8.0 μg/mL. A significant reduction biofilm mass was...
Colorectal cancer (CRC) is still a leading cause of death worldwide. Recent studies have pointed to an important role microRNAs in carcinogenesis. Several are described as aberrantly expressed CRC tissues and the serum patients. However, functional outcomes microRNA aberrant expression need be explored at cellular level. Here, we aimed investigate effects samples proliferation cell line.We transfected 31 mimics into HCT116 cells. Total number live propidium iodide negative (PI-) dead (PI+)...
Glioblastoma (GBM) is the most lethal and frequent type of brain tumor, leading patients to death in approximately 14 months after diagnosis. GBM treatment consists surgical removal followed by radio chemotherapy. However, tumors commonly relapse promotes only a slight increase patient survival. Thus, uncovering cellular mechanisms involved resistance utmost interest, use cell lines has been shown be an extremely important tool. In this work, exploration RNAseq data from different revealed...
Head and neck squamous cell carcinoma (HNSCC) is among the most common cancer types. Metastasis, main cause of death by cancer, can be promoted an inflammatory microenvironment, which induces epithelial-mesenchymal transition (EMT) through a NF-kB-mediated stabilization Snail. Here, we aimed to explore how microRNAs (miRs) affect survival EMT in HNSCC cells under microenvironment. By using high-content screening (HCS) approach, evaluated alterations morphometric parameters, as well...