A5053824930- Pharmaceutical Practices and Patient Outcomes
- Dementia and Cognitive Impairment Research
- Geriatric Care and Nursing Homes
- Intensive Care Unit Cognitive Disorders
- Research in Social Sciences
- Frailty in Older Adults
- Health disparities and outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Schizophrenia research and treatment
- Pain Management and Opioid Use
- Health, psychology, and well-being
- Opioid Use Disorder Treatment
- Health and Wellbeing Research
- Employment and Welfare Studies
- Sleep and related disorders
- Balance, Gait, and Falls Prevention
- Delphi Technique in Research
- Blood Pressure and Hypertension Studies
- Sleep and Wakefulness Research
- Clinical practice guidelines implementation
- Human Resource Development and Performance Evaluation
- Anesthesia and Sedative Agents
- Ocular Disorders and Treatments
- Ocular Oncology and Treatments
- Nursing Roles and Practices
University of Helsinki
1978-2024
Helsinki University Hospital
2023-2024
City of Helsinki
2017-2022
Hospital District of Helsinki and Uusimaa
2019
Abstract Purpose We compared the prevalence of COVID-19 and related mortality in nursing homes (NHs) 14 countries until October 2021. explored relationship between NHs with average size deaths at a population level. Methods The total number cases COVID-19-related all as well NH beds were provided by representatives countries. level respective figures each country up to Results There was wide variation observed significant correlation that mean deaths. Conclusion Side-by-side comparisons...
The aging of our societies leads to a higher prevalence multimorbidity and therefore polypharmacy, which often results in inappropriate drug treatment. To address this issue, numerous listing approaches, such as the Fit fOR Aged (FORTA) list have been developed. FORTA's positive impact on quality medications relevant clinical outcomes has shown. Based new emerging evidence experiences with existing FORTA lists, we aimed update lists several European countries/regions.Two-step Delphi...
Background Pain is undertreated in older populations. At the same time, increased use of opioids concern Western world. Aims We sought to analyze temporal trends musculoskeletal pain and prescribed analgesic treatment among community-dwelling people aged 75–95 years using cross-sectional cohort data spanning 20 years. Methods The Helsinki Aging Study recruited random samples 75, 80, 85, 90, 95 1999, 2009, 2019. In total, 5707 persons participated study. participants reported their medical...
Abstract Background Frailty Index (FI) reflects health, functioning and well-being of older people. It is valuable to compare how frailty has changed over time in ageing cohorts. This study aims examine trends among 75–95-year-old men women three decades. Methods The Helsinki Ageing Study started 1989 includes repeated cross-sectional postal surveys every 10 years examining community-dwelling cohorts people (75, 80, 85, 90 95 years). FI comprises the same 36 items each cohort. Results mean...
Abstract Background Falls in long-term care are common. The aim of our study was to explore how medication use is associated with incidence falls, related consequences, and all-cause mortality among residents. Methods Five hundred thirty two residents aged 65 years or older participated this longitudinal cohort 2018–2021. Data on were retrieved from medical records. Polypharmacy defined as 5–10 medications excessive polypharmacy > 10 medications. numbers injuries, fractures,...
The use of drugs with anticholinergic properties (DAPs) is common among older adults despite their known adverse effects, such as cognitive decline. Professionals should pay attention to DAPs, since evidence on effects has been accumulating during the last decade. However, our knowledge previous studies exploring temporal trends in DAPs are scarce. aim this study was assess from 2003 2017 long-term care facilities Helsinki. Four cross-sectional were conducted 2003, 2007, 2011, and 2017....
Introduction: Loneliness, social inactivity, and isolation are intertwined concepts. When assessed separately, they indicate poor well-being, adverse health effects, increased mortality. Studies exploring overlapping comparing the prognosis of these concepts scarce. We investigated (1) loneliness, isolation, (2) characteristics groups: group 0 (not lonely, socially inactive, or isolated), 1 (lonely), 2 lonely but inactive and/or (3) health-related quality life (HRQoL), psychological...
Efficacy and side effects of flurazepam 15 mg, fosazepam 60 nitrazepam 5 mg were studied in 17 psychogeriatric patients. The drugs equipotent maintaining sleep but had more than the other hypnotics, it induced a rebound insomnia after withdrawal. All hypnotics lost some their efficacy towards end 7 days' administration. Patients with evident cerebrovascular disease vulnerable to benzodiazepine hypnotics. did not correlate age patient. In addition, no correlations found between serum levels...
Recently, the concept of successful ageing has shifted from healthy to active ageing, latter emphasising even more subjective perspective. Active agency is a marker for better functioning. However, lacks clear definition so far. The specific aims study were identify determinants being actively engaged in life (BAEL), explore changes BAEL over 3 decades, and prognostic value BAEL.This repeated cross-sectional cohort older (≥ 75 years) community-dwelling people Helsinki 1989 (N = 552), 1999...
Anticholinergic burden defined by the Risk Scale (ARS) has been associated with cognitive and functional decline. Associations health-related quality of life (HRQoL) have scarcely studied. The aim this study was to examine association between anticholinergic HRQoL among older people living in long-term care. Further, we investigated whether there is an interaction ARS score certain underlying conditions.
Knowledge of the adverse effects drugs with anticholinergic properties (DAPs) has increased in recent decades. However, research on temporal trends clinical use DAPs is still sparse. The aim this study was to investigate DAP over two decades older community-dwelling population and explore medication classes contributing DAPs. involved random samples ≥ 75-year-old Helsinki citizens 1999, 2009, 2019 from Ageing Study. A postal questionnaire inquired about their health, functioning,...
Abstract Objective To explore the co-prescribing of analgesic and/or adjuvant medications among residents Australian and Finnish nursing homes. Method Secondary cross-sectional analyses prescribing data from 12 homes in 2019 53 or assisted living facilities 2017−2018. Demographic characteristics medication were extracted medical records administration charts. Co-prescribing was defined as more than one (acetaminophen, nonsteroidal anti-inflammatory drugs opioids) (gabapentinoids, tricyclic...
Loneliness is common among older adults in institutional settings. It leads to adverse effects on health and wellbeing, for which nature contact with peers turn may have positive impact. However, the of engagement not been studied randomised controlled trials (RCT). The "Friends Nature" (FIN) group intervention RCT lonely Helsinki assisted living facilities (ALFs) aims explore peer-related experiences loneliness health-related quality life (HRQoL). In this study we aim describe participants'...
The aim of Delirium Café was to try a new learning method increase awareness delirium and improve care in an acute hospital setting Helsinki, Finland.World Café-an active method, with four facilitators stations covering important aspects recognition management, used.22 junior doctors 4 members the senior staff participated event on 13th March 2019, World Awareness Day (WDAD). Nobody dropped out during 1 h training. Feedback educational positive.Delirium seems be both feasible applicable as...