A5100615748- Diabetes Treatment and Management
- Diabetes Management and Research
- Nutrition and Health in Aging
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Liver Disease Diagnosis and Treatment
- Metabolism, Diabetes, and Cancer
- Pancreatic function and diabetes
- Lipoproteins and Cardiovascular Health
- Diet, Metabolism, and Disease
- Thyroid Disorders and Treatments
- Diet and metabolism studies
- Bone health and osteoporosis research
- Thyroid Cancer Diagnosis and Treatment
- Diabetes and associated disorders
- Vitamin D Research Studies
- Bariatric Surgery and Outcomes
- Cancer, Lipids, and Metabolism
- Consumer Perception and Purchasing Behavior
- Body Composition Measurement Techniques
- Nutritional Studies and Diet
- Chronic Kidney Disease and Diabetes
- Chronic Disease Management Strategies
- Liver Disease and Transplantation
- Neuropeptides and Animal Physiology
- Diverse Topics in Contemporary Research
Korea University
2016-2025
Samsung Medical Center
2023-2025
Sungkyunkwan University
2023-2025
Korea University Medical Center
2009-2025
Seoul National University Bundang Hospital
2025
Kangbuk Samsung Hospital
2025
St. Vincent's Hospital
2025
Keimyung University
2024
Korean Diabetes Association
2024
Daejeon University
2022
Abstract We propose a new anthropometric index, weight-adjusted-waist index (WWI), to assess adiposity by standardizing waist circumference (WC) for weight. WWI, calculated as WC (cm) divided the square root of weight (kg) (cm/√kg), was measured from 465,629 subjects in Korean nationwide cohort (2008–2013). Cox regression analysis used compare WWI with BMI, WC, waist-to-height ratio (WHtR), and body shape (ABSI) cardiometabolic morbidity mortality risk diagnostic prognostic prediction...
Abstract Background Age-related changes in body composition include decreased muscle mass and preserved or increased fat mass. There is no anthropometric index to assess both Methods Using a cross-sectional sample of 602 participants aged ≥65 years from the Ansan Geriatric study, we evaluated association weight-adjusted waist (WWI) with compared these (BMI) circumference (WC). WWI was calculated as WC (cm) divided by square root weight (kg). Body measured using bioelectrical impedance...
The weight-adjusted waist index (WWI) reflected body compositional changes with aging. This study was to investigate the association of WWI abdominal fat and muscle mass in a diverse race/ethnic population.Computed tomography (CT) data from 1,946 participants for areas Multi-Ethnic Study Atherosclerosis (785 Whites, 252 Asians, 406 African American, 503 Hispanics) were used. Among them, 595 underwent repeated CT. calculated as circumference (cm) divided by square root weight (kg)....
Unhealthy body composition, including high fat mass, low muscle mass and bone is a critical health issue in adults. The weight-adjusted waist index (WWI) estimates may have implications for health. We examined its association with composition outcomes large Korean adult cohort.This study used data from the National Health Nutrition Examination Survey (2008-2011). WWI was calculated as circumference (cm) divided by square root of weight (kg). Dual-energy X-ray absorptiometry to measure...
This study aimed to investigate the prevalence, management, and comorbidities of diabetes mellitus among Korean adults. Data from Korea National Health Nutrition Examination Survey (2019-2022) were analyzed assess treatment, risk factors, diabetes. Comparisons between young older adults with emphasized. Among aged ≥30 years, prevalence is 15.5% during 2021-2022. Of these, 74.7% aware their condition, 70.9% received antidiabetic only 32.4% achieved glycosylated hemoglobin (HbA1c) <6.5%....
Objectives To examine the relationship between depression and various components of body composition, including fat muscle, in elderly Koreans. Design A cross-sectional sample a longitudinal cohort from Ansan Geriatric (AGE) Study. Setting Elderly people living urban area (Ansan City, South Korea). Participants Eight hundred thirty-six participants (378 male, 458 female) aged 60 older were recruited April 2006 to January 2008. Measurements Depressive symptoms examined using Korean version...
Background The association between body mass index (BMI) and mortality is not conclusive, especially in East Asian populations. Furthermore, the has been neither supported by recent data, nor assessed after controlling for weight changes. Methods We evaluated relationship BMI all-cause or cause-specific mortality, using prospective cohort data National Health Insurance Service Korea, which consisted of more than one million subjects. A total 153,484 Korean adults over 30 years age without...
As the metabolic significance of sarcopenic obesity (SO) is revealed, finding an appropriate index to detect SO important, especially for type 2 diabetes mellitus (T2DM) patients with accompanying dysfunction.Participants (n=515) from Korea Guro Diabetes Program were included compare how well waist circumference (WC), hip ratio (WHR), height (WHtR), and weight-adjusted (WWI) predict in newly diagnosed T2DM patients. Sarcopenia was defined based on guidelines 2019 Asian Working Group as both...
Background: To investigate the prevalence, incidence, comorbidities, and management status of diabetic kidney disease (DKD) diabetes-related end-stage (ESKD) in South Korea.Methods: We used Korea National Health Nutrition Examination Survey data (2019 to 2021, <i>n</i>=2,665) for evaluation control rate glycemia comorbidities DKD, Korean Insurance Service-customized database (2008 2019, <i>n</i>=3,950,857) trends incidence prevalence ESKD, renin-angiotensin system...
To assess the comparative effectiveness of sodium-glucose cotransporter 2 inhibitors (SGLT2i), thiazolidinediones (TZD), and dipeptidyl peptidase-4 (DPP-4i) for cardiorenal outcomes mortality in individuals with type diabetes a prior stroke. Using Korean National Health Insurance Service database from 2014 to 2021, new-user cohort was established through propensity score matching SGLT2i, TZD, DPP-4i. The primary were major adverse cardiovascular events (MACE), comprising myocardial...
BackgroundAntithyroid drug (ATD) treatment is the preferred initial for Graves' disease (GD) in South Korea, despite higher failure rates than radioactive iodine (RAI) therapy or thyroidectomy. This study aimed to evaluate incidence of associated with primary modalities GD real-world practice. MethodsWe included 452,001 patients diagnosed between 2004 and 2020 from Korean National Health Insurance Service-National Information Database. Treatment was defined as switching ATD, RAI,...
Abstract Although liver enzymes, such as γ-glutamyltransferase (GGT), alanine aminotransferase (ALT), and aspartate (AST), have recently been suggested risk factors for cardiovascular diseases (CVD), impact on mortality after myocardial infarction (MI) or ischemic stroke (IS) was not previously examined. Using a population-based, nationwide cohort database, we explored the implication of GGT aminotransferases development CVD all-cause during median 9.1 years follow-up. Among 16,624,006...
Abstract Objective To investigate whether fenofibrate as add-on to statin treatment reduce persistent cardiovascular risk in adults with metabolic syndrome a real world setting. Design Propensity matched cohort study. Setting Population based Korea. Participants 29 771 (≥40 years) receiving treatment. 2156 participants combined (statin plus fenofibrate) were weighted on propensity score 1:5 ratio 8549 using only Main outcome measure Primary was composite events including incident coronary...
Abstract Background & Aims The course of NAFLD (nonalcoholic fatty liver disease) and associated factors in nonobese subjects are not well established. We investigated contributing for the development regression Koreans, whether they would differ from those obese subjects. Methods Two thousand three hundred seven adults aged over 18 years participated this longitudinal observational study. mean duration follow‐up was 28.7 (±13.2) months. participants were divided into two groups...
Abstract The novel neuropeptide spexin (SPX) was discovered to activate galanin receptor 2 (GALR2) and 3 (GALR3) but not 1 (GALR1). Although GALR2 is known display a function, particularly in anxiety, depression, appetite regulation, the further determination of its function would benefit from more stable selective agonist that acts only at GALR2. In present study, we developed GALR2-specific with increased stability serum. As (GAL) showed low affinity GALR3, residues SPX were replaced those...
Melatonin plays an important role in regulating circadian rhythms. It also acts as a potent antioxidant and regulates glucose lipid metabolism, although the exact action mechanism is not clear. The α2-HS-glycoprotein gene (AHSG) its protein, fetuin-A (FETUA), are one of hepatokines known to be associated with insulin resistance type 2 diabetes. aim this study was determine whether melatonin improves hepatic steatosis FETUA-dependent manner. In HepG2 cells treated 300 μmol/L palmitic acid,...
Colonic Mucosal Necrosis Following Administration of Calcium Polystryrene Sulfonate (Kalimate) in a Uremic PatientColonic necrosis is known as rare complication following the administration Kayexalate (sodium polystryrene sulfonate) sorbitol.We report case colonic mucosal Kalimate (calcium sulfonate), an analogue without sorbitol 34-yr-old man.He had history hypertension and uremia.During management intracranial hemorrhage, hyperkalemia developed.Kalimate was administered orally enema...