A5032854994- Nematode management and characterization studies
- Parasite Biology and Host Interactions
- Entomopathogenic Microorganisms in Pest Control
- Genetics, Aging, and Longevity in Model Organisms
- Insects and Parasite Interactions
- Insect symbiosis and bacterial influences
- Insect and Arachnid Ecology and Behavior
- Genomics, phytochemicals, and oxidative stress
- Intracranial Aneurysms: Treatment and Complications
- Trigeminal Neuralgia and Treatments
- Marine Biology and Ecology Research
- RNA Research and Splicing
- Potato Plant Research
- Circadian rhythm and melatonin
- Neurogenesis and neuroplasticity mechanisms
- Mollusks and Parasites Studies
- Moyamoya disease diagnosis and treatment
- Plant Pathogens and Fungal Diseases
- Reproductive Biology and Fertility
- Meningioma and schwannoma management
- Cell Adhesion Molecules Research
- Facial Nerve Paralysis Treatment and Research
- Atrial Fibrillation Management and Outcomes
- Insect and Pesticide Research
- Plant and animal studies
Chubu University
2015-2024
Research Institute for Bioscience and Biotechnology
2023
Aichi University
2023
Matsumoto University
2023
Kasugai Municipal Hospital
2023
Shimane University
2021-2022
Tokai University
2022
University College London
2019
Thrombosis Research Institute
2019
Kyoto University
2002-2017
Bursaphelenchus xylophilus is the nematode responsible for a devastating epidemic of pine wilt disease in Asia and Europe, represents recent, independent origin plant parasitism nematodes, ecologically taxonomically distinct from other nematodes which genomic data available. As well as being an important pathogen, B. genome thus provides unique opportunity to study evolution mechanism parasitism. Here, we present high-quality draft sequence inbred line xylophilus, use this investigate...
Sirtuin1 (Sirt1), a mammalian homolog of yeast Sir2, deacetylates the tumor suppressor protein p53 and attenuates p53-mediated cell death. Necdin, p53-interacting expressed predominantly in postmitotic neurons, is melanoma antigen family that promotes neuronal differentiation survival. In mammals, necdin gene ( Ndn ) maternally imprinted, mutant mice carrying mutated paternal show abnormalities development. Here we report regulates acetylation status via Sirt1 to suppress p53-dependent...
Three new species of the genus Longior Travassos & Kloss, 1958 are described and illustrated, namely L. surieli n. sp. in Antillanax dominicanus (Doesburg, 1953) from Dominican Republic, lamothei Passalus punctiger Le Peletier Serville, 1825 Mexico Colombia zumpimito P. punctatostriatus Percheron, 1835 Mexico. These constitute first records for aforementioned countries, rising to nine genus. The can be differentiated mainly by length their body, oesophagus tail both sexes, extension...
Aoruroides chubudaigaku n. sp. (Nematoda: Oxyuridomorpha: Thelastomatidae) is described from the wood-burrowing cockroach Panesthia angustipennis spadica (Shiraki, 1906) (Blattodea: Blaberidae: Panesthiinae) Aichi prefecture, Japan. Females of A. are similar to costaricensis Carreno Tuhela, 2011 by position nerve ring at level first third isthmus, body length and comparative measurements oesophagus tail. They differ excretory pore vulva. The males characterized absence ornamentations in...
Klossnema viguerasi n. sp. (Nematoda: Oxyuridomorpha: Hystrignathidae) is described from the passalid beetle Antillanax pertyi (Kaup, 1869), endemic to Cuba. The females of K. are morphologically similar but slightly longer than repentina Cordeiro & Artigas, 1983 (1.143 mm vs. 1.000 mm). Both species differ in that has a procorpus (139 µm 110 µm), isthmus (39 24 and tail length (28 21 µm). distance vulva anterior end also new (0.748 0.650 males larger (0.980 0.800 mm), their shorter (38...
Abstract Neurons rely heavily on mitochondria for their function and survival. Mitochondrial dysfunction contributes to the pathogenesis of neurodegenerative diseases such as Parkinson’s disease. PGC-1α is a master regulator mitochondrial biogenesis function. Here we identify necdin potent stabilizer that promotes via in mammalian neurons. Expression genes encoding mitochondria-specific proteins decreases significantly necdin-null cortical neurons, where expression protein are reduced....
Blattophila peregrinata Carreno, 2017 (Nematoda: Oxyuridomorpha: Thelastomatidae) is proposed as a junior synonym of Suifunema peregrinatum (Carreno, 2017) n. comb., based on the revision type material S. caudelli Chitwood, 1932, and only species genus. The permitted emendation some features original descriptions, namely position nerve ring at level corpus instead isthmus female genital tract didelphic-prodelphic didelphic-amphidelphic. males comb. are ones known for Thus, an amended generic...
Rhigonema naylae n. sp. (Rhigonematomorpha: Rhigonematidae) is described from the hindgut of polydesmid millipede Parafontaria laminata (Attems, 1909) (Polydesmida: Xystodesmidae), Aichi prefecture, Japan. The new species characterized by having a medium sized body in both sexes, cephalic collar partially fused to cuticle, but not overhanging contour; cervical region densely covered short, fine microtrichs that extend posterior margin ca. 1.5 oesophagus lengths basal bulb; tail short and...
Coynema poeyi (Coy, García & Álvarez, 1993) (Oxyuridomorpha: Hystrignathidae) is redescribed and illustrated with the aid of SEM. New features cephalic end both sexes copulatory papillae pattern males were observed generic diagnosis emended in order to include such features. locality records are given. The phylogenetic position species inferred on basis D2-D3 segment LSU rDNA. C. located basal a monophyletic clade formed by other hystrignathids: two Longior Travassos Kloss, 1958 Hystrignathus sp.
The females of Xyo pseudohystrix Travassos & Kloss, 1958 (Nematoda: Oxyuridomorpha: Hystrignathidae) are redescribed and illustrated with the aid SEM. New features cephalic end, arrangement cervical spines genital tract were observed. taxonomic status species is discussed on basis discrepancies generic diagnosis Cobb, 1898. Due to lack proper information genus incertae sedis proposed. identity males was confirmed by molecular studies morphology specimens previously assigned Christie...
Travassosinema claudiae n. sp. is described from the hindgut of polydesmid millipede Parafontaria laminata (Attems, 1909) (Polydesmida: Xystodesmidae) Aichi prefecture, Japan. Females new species resemble T. thyropygi Hunt, 1996 and travassosi Rao, 1958 by lacking lateral alae constriction body posterior to level vulva. differs its shorter tail, larger eggs. Also, nerve ring located in procorpus-isthmus junction opposition thyropygi, where just anterior basal bulb. can be differentiated eggs...
Lepidonema magnum Morffe & García, 2010 (Nematoda: Oxyuridomorpha: Hystrignathidae) is redescribed and illustrated with the aid of SEM. New features cephalic end genital tract females were observed. locality records are given. The phylogenetic position species inferred on basis D2-D3 segment 28S LSU rDNA 18S SSU rDNA. L. forms a monophyletic clade formed by other hystrignathids: Coynema poeyi (Coy, García Álvarez, 1993), two Longior Travassos Kloss, 1958 Hystrignathus Leidy, 1850.
As acrylamide is a known neurotoxin for many animals and potential carcinogen humans, it came as surprise when the Swedish National Food Agency Stockholm University reported in 2002 that formed during frying or baking of foods. We report here genomic proteomic analyses on genes proteins Caenorhabditis elegans exposed to 500 mg/l acrylamide. Of 21,120 profiled, 409 were more than twofold upregulated 111 downregulated. Upregulated included encode detoxification enzymes such glutathione...
Background Electrophilic xenobiotics and endogenous products from oxidative stresses induce the glutathione S-transferases (GSTs), which form a large family within phase II enzymes over both animal plant kingdoms. The GSTs thus induced in turn detoxify these external as well internal stresses. Because are often linked to ageing damage health, induction of without causing adverse effects would be beneficial slowing down keeping healthy conditions. Methodology/Principal Findings We have tested...
White adipose tissues are composed mainly of white fat cells (adipocytes), which play a key role in energy storage and metabolism. adipocytes terminally differentiated postmitotic arise from their progenitor (preadipocytes) or mesenchymal stem residing tissues. Thus, adipocyte number is most likely controlled by the rate preadipocyte proliferation, may contribute to etiology obesity. However, little known about molecular mechanisms that regulate proliferation during tissue development....
Buzionema lutgardae n. sp. (Nematoda: Oxyuridomorpha: Thelastomatidae) is described from the cockroach Byrsotria (Blattaria: Blaberidae), endemic to Cuba. Females of B. are shorter than those validum Kloss, 1966 (1600–2150 µm vs. 3131–3378 µm), but oesophagus comparatively longer (b = 2.96–3.77 4.65–4.87). The lateral alae new species extend ca. midpoint cylindrical part procorpus level anus in contrast base basal bulb validum. males (780–940 1177–1423 µm) and their end at some distance...
Abstract Sex determination mechanisms evolve surprisingly rapidly, yet little is known in the large nematode phylum other than for Caenorhabditis elegans , which relies on chromosomal XX-XO sex and a dosage compensation mechanism. Here we analyze by sex-specific genome sequencing genetic analysis two fungal feeding/plant-parasitic Bursaphelenchus nematodes find that their differentiation more likely triggered random, epigenetic regulation well-known of or environmental determination. There...
Abstract Background Pine wilt disease (PWD) caused by the pinewood nematode Bursaphelenchus xylophilus is one of most serious forest diseases in world. The role B. -associated bacteria PWD and their interaction with nematode, have recently been under substantial investigation. Several studies report a potential contribution for development, either as helper to enhance pathogenicity or pathogenic agent expressing interesting traits related lifestyle host-adaptation. Results We investigated...
Cockroaches are parasitized by thelastomatid nematodes, which live in an obligate manner their hindgut and interact with the resident microbial community. In present study, a composition analysis was performed on gut microbiome of Periplaneta fuliginosa P. americana to investigate natural artificial infection nematodes. Nine libraries 16S rRNA gene V3–V4 region were prepared for pyrosequencing. We examined complete (fore-, mid-, hindgut) lab-reared naturally infected parasitic nematode...
α-terthienyl is an allelochemical derived from the roots of marigold (Tagetes spp.), which used to suppress plant parasitic nematodes. We investigated nematicidal activity against model organism Caenorhabditis elegans and root-knot nematode, Meloidogyne incognita. As reported previously, action was much higher after photoactivation, but still effective C. dauer larvae M. incognita second stage juveniles, even without photoactivation. Expression induction two major enzymes, glutathione...
Pine wilt disease (PWD) has a tremendous impact on worldwide forestlands, both from the environmental and economical viewpoints. Monochamus sp., xylophagous insect Cerambycidae family, plays an important role in dissemination of pinewood nematode, Bursaphelenchus xylophilus, primary pathogenic agent PWD. This study investigates, for first time, bacterial communities galloprovincialis collected Portuguese Pinus pinaster trees B. xylophilus free, using metagenomics approach. Overall, our...