A5004639113- Pharmaceutical and Antibiotic Environmental Impacts
- Forensic Toxicology and Drug Analysis
- Analytical chemistry methods development
- Metabolomics and Mass Spectrometry Studies
- Advanced Chemical Sensor Technologies
- Analytical Chemistry and Chromatography
- Mass Spectrometry Techniques and Applications
- Microplastics and Plastic Pollution
- Computational Drug Discovery Methods
- SARS-CoV-2 detection and testing
- Pesticide Residue Analysis and Safety
- Environmental Toxicology and Ecotoxicology
- Toxic Organic Pollutants Impact
- HIV, Drug Use, Sexual Risk
- Water Quality Monitoring and Analysis
- Nutritional Studies and Diet
- Water Quality and Pollution Assessment
- Antibiotics Pharmacokinetics and Efficacy
- Recycling and Waste Management Techniques
- Opioid Use Disorder Treatment
- Smart Materials for Construction
- Isotope Analysis in Ecology
- Psychedelics and Drug Studies
- Air Quality Monitoring and Forecasting
- Healthcare and Environmental Waste Management
Thrive
2023
Norwegian Institute for Water Research
2014-2023
University of Otago
2022
AgroParisTech
2018
Université Paris-Saclay
2018
Université Paris-Sud
2018
Centre National de la Recherche Scientifique
2018
Health Sciences Authority
2018
Peking University
2018
Institute of Environmental Assessment and Water Research
2018
The aim of this study was to integrally address the uncertainty associated with all steps used estimate community drug consumption through chemical analysis sewage biomarkers illicit drugs. Uncertainty has been evaluated for sampling, analysis, stability in sewage, back-calculation use (specific case cocaine), and estimation population size a catchment using data collected from recent Europe-wide investigation available literature. quality sampling protocols analytical measurements by...
Abstract Aims To perform wastewater analyses to assess spatial differences and temporal changes of illicit drug use in a large E uropean population. Design Analyses raw over 1‐week period 2012 2013. Setting Participants Catchment areas treatment plants ( WWTP s) across urope, as follows: 2012: 25 s 11 countries (23 cities, total population 11.50 million); 2013: 47 21 (42 24.74 million). Measurements Excretion products five drugs (cocaine, amphetamine, ecstasy, methamphetamine, cannabis) were...
Abstract Background and aims Wastewater‐based epidemiology is an additional indicator of drug use that gaining reliability to complement the current established panel indicators. The this study were to: (i) assess spatial temporal trends population‐normalized mass loads benzoylecgonine, amphetamine, methamphetamine 3,4‐methylenedioxymethamphetamine (MDMA) in raw wastewater over 7 years (2011–17); (ii) address overall by estimating average number combined doses consumed per day each city;...
Monitoring the scale of pharmaceuticals, illicit and licit drugs consumption is important to assess needs law enforcement public health, provides more information about different trends within countries. Community drug use patterns are usually described by national surveys, sales seizure data. Wastewater-based epidemiology (WBE) has been shown be a reliable approach complementing such surveys. This study aims compare correlate estimates drugs, alcohol, nicotine caffeine from wastewater...
The chemical pollution crisis severely threatens human and environmental health globally. To tackle this challenge the establishment of an overarching international science-policy body has recently been suggested. We strongly support initiative based on awareness that humanity already likely left safe operating space within planetary boundaries for novel entities including pollution. Immediate action is essential needs to be informed by sound scientific knowledge data compiled critically...
Polar organic chemical integrative samplers (POCIS) were calibrated in situ for selected illicit drugs and their metabolites at a sewage treatment works. Eleven out of 13 target compounds detected eight those exhibited linear uptake kinetics with sampling rates between 0.035 0.150 L d–1. Subsequently POCIS deployed 2 week periods over the course whole year, order to examine trends drug usage. Amphetamine methamphetamine showed several similar peaks concentration during year as did cocaine...
Background: The quantitative measurement of urinary metabolites in sewage streams and the subsequent estimation consumption rates parent compounds have previously been demonstrated for pharmaceuticals narcotics. Ethyl sulfate ethyl glucuronide are excreted urine following ingestion alcohol, useful biomarkers identification acute alcohol consumption. This study reports a novel ion-exchange-mediated chromatographic method effluent, presents calculation purposes relating resulting...
Abstract Marine debris is a global environmental issue. Smoked cigarette filters are the predominant coastal litter item; 4.5 trillion littered annually, presenting source of bioplastic microfibres (cellulose acetate) and harmful toxicants to marine environments. Despite human health risks associated with smoking, little known hazards present life. Here we studied impacts smoked filter on polychaete worm Hediste diversicolor (ragworm), widespread inhabitant sediments. Ragworms exposed in...
A key challenge in the environmental and exposure sciences is to establish experimental evidence of role chemical human systems. High resolution accurate tandem mass spectrometry (HRMS) increasingly being used for analysis samples. One lauded benefit HRMS possibility retrospectively process data (previously omitted) compounds that has led archiving data. Archived affords exploiting historical rapidly effectively temporal spatial occurrence newly identified contaminants through retrospective...
Quantitative measurement of drug consumption biomarkers in wastewater can provide objective information on community use patterns and trends. This study presents the alcohol 20 cities across 11 countries through wastewater-based epidemiology (WBE), reports application these data for risk assessment a population scale using margin exposure (MOE) approach. Raw 24-h composite samples were collected over one-week period from following common protocol. For each sample specific stable biomarker,...
Wastewater-based epidemiology is an established approach for quantifying community drug use and has recently been applied to estimate population exposure contaminants such as pesticides phthalate plasticizers. A major source of uncertainty in the weighted biomarker loads generated related estimating number people present a sewer catchment at time sample collection. Here, quantified from mobile device-based activity patterns was used provide dynamic normalized illicit drugs pharmaceuticals...
Environmental monitoring data for tire road wear particles are vastly limited compared to those other microplastics, primarily due analytical challenges with quantification. Recently, two ISO technical specifications have been released using pyrolysis GC-MS However, these methods major assumptions, including that the content of natural and synthetic rubber in tread is constant across formulations products chosen selective. This study analyzed a wide range commercially available tires from...
The COVID-19 outbreak has forced countries to introduce severe restrictive measures contain its spread. In particular, physical distancing and restriction of movement have had important consequences on human behaviour potentially also illicit drug use supply. These changes can be associated with additional risks for users, in particular due reduced access prevention harm reduction activities. Furthermore, there been limitations the amount data about which collected restrictions. To goal this...
Road pollution is one of the major sources microplastic particles to environment. The distribution tire, polymer-modified bitumen (PMB) and tire road wear (TRWP) in different tunnel compartments were explored: surface, gully-pots wash water. A new method for calculating TRWP using Monte Carlo simulation presented. highest concentrations on surface side bank (tire:13.4 ± 5.67;PMB:9.39 3.96; TRWP:22.9 8.19 mg/m2), comparable previous studies, at outlet (tire:7.72 11.2; PMB:5.40 7.84; TRWP:11.2...
The analysis of sewage for the residues commonly used illicit drugs has successfully been applied as a suitable approach estimating community drug use. market is increasingly dynamic with new substances continually being marketed recreational purposes. In this study, ultra‐high pressure liquid chromatography coupled to tandem mass spectrometry (UHPLC‐MS/MS) was simultaneously and quantitatively detect exogenous biomarkers classes in collected from three different Norwegian cities (Oslo,...
Nontarget analysis is considered one of the most comprehensive tools for identification unknown compounds in a complex sample analyzed via liquid chromatography coupled to high-resolution mass spectrometry (LC-HRMS). Due complexity data generated LC-HRMS, data-dependent acquisition mode, which produces MS2 spectra limited number precursor ions, has been common approaches used during nontarget screening. However, data-independent mode highly that require proper deconvolution and library...