A5100387978- Bone and Joint Diseases
- Inflammatory Biomarkers in Disease Prognosis
- Acute Kidney Injury Research
- Bone health and treatments
- Legal Education and Practice Innovations
- Criminal Law and Evidence
- Iron Metabolism and Disorders
- Chronic Kidney Disease and Diabetes
- Kidney Stones and Urolithiasis Treatments
- Peroxisome Proliferator-Activated Receptors
- Regional Development and Environment
- Adipokines, Inflammation, and Metabolic Diseases
- Blood groups and transfusion
- Clinical Nutrition and Gastroenterology
- Angiogenesis and VEGF in Cancer
- Muscle and Compartmental Disorders
- Hip disorders and treatments
- Advanced Proteomics Techniques and Applications
- Platelet Disorders and Treatments
- Osteoarthritis Treatment and Mechanisms
- Monoclonal and Polyclonal Antibodies Research
- Renal Diseases and Glomerulopathies
- Streptococcal Infections and Treatments
- Lipid metabolism and disorders
- Venous Thromboembolism Diagnosis and Management
Second Affiliated Hospital of Inner Mongolia Medical University
2021
Mongolian National University
2021
Tang Hospital
2017
Peking University
2008-2015
Peking University First Hospital
2008-2015
Shanghai Second People's Hospital
2012
Chinese PLA General Hospital
2010
First Affiliated Hospital of Gannan Medical University
2010
Second Affiliated Hospital of Xi'an Jiaotong University
2007
Recent evidence suggests that platelet activation and angiotensin II may each contribute to glomerular inflammation fibrosis. Clopidogrel inhibits also reduce inflammation. This study investigated the anti-inflammatory renoprotective effects of clopidogrel irbesartan in five-sixths nephrectomy rat model chronic kidney disease. After 8 wk treatment, 24-h proteinuria, serum creatinine, histologic scores sclerosis tubulointerstitial damage were significantly lower treated compared with...
IgA nephropathy (IgAN) is one of the most common types glomerulonephritis worldwide and diagnosed only with a renal biopsy. The purpose present studies was to identify potential biomarkers for non-invasive diagnosis IgAN. combination magnetic bead separation system matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) used analyze urinary peptides IgAN patients, other glomerulopathy healthy controls. ClinProTools v.2.0 software also applied establish...
The aim of the study was to investigate effects high-volume continuous renal replacement therapy (HV-CRRT) on procalcitonin (PCT), tumor necrosis factor-α (TNF-α), interleukin-4 (IL-4), IL-6, IL-8 and IL-10 in acute pancreatitis complicated by failure. Eighty-six patients with failure were selected from September 2014 2016 our hospital, treated veno-venous hemofiltration (CVVH). randomly divided into observation group, HV-CVVH model a displacement rate 4 l/h, control normal capacity 2 l/h....
Steroid-induced osteonecrosis of the femoral head (ONFH) is a disease bone. Metabolism and genetic factors are generally considered to play an important role. The purpose this study was investigate relationship between single-nucleotide polymorphisms (SNPs) in MIR17HG MIR155HG risk steroid-induced ONFH population northern China.A total 199 patients 506 healthy controls were recruited for study. Four SNPs seven genotyped by Sequenom MassARRAY. ORs 95% CIs used evaluate these ONFH.In...
Purpose: To investigate the effect of a combination thymosin α1 with conventional regimen on APC and IL-1R1 levels in children with severe pneumonia, to provide reference for its clinical treatment.Methods: A total 96 pneumonia over period two years were divided into control observation groups (48 cases per group) by random number table method. The patients consisted 46 males 50 females within age range 0.1 - 6 (mean = 3.0 ± 1.2 years), mean duration 13.4 2.2 days). Their acute physiology...
Objective To establish a new method for monitoring aspirin response by platelet activated-release experiment.Methods The platelets in whole blood were activated ARA,and the MPC was measured hematology analyzer.Blood samples drawn from five healthy volunteers measuring MPC,LTAARA and membrane CD62P expression.Blood mixed thoroughly right after venipuncture. concentration of ARA (0,0. 5,1.0,1.5,5.0 10. 0 mmol/L) time activation (5,10,20,30,40,50,60,70,80 90 min 37℃ water bathe) optimized to...
Objeetive To explore change of platelet glycoproteins Ⅵ(GPⅥ)in patients with type 2 diabetes mellitus and its clinical significance.Methods The surface expression glycoprotein Ⅵ was determined by flow cytometry in 56 61 normal individuals.Plasma GP concentration measured ELISA 30 mellitus.Platelet CD62P analyzed HbA1c Datients mellitus.Results geometric mean fluorescence GPⅥ 93.66±35.24,which significantly enhanced compared subjects (62.83±24.2)(t=-4.927,P＜0.05).Nine were positive plasma...
Abstract IntroductionSteroid-induced osteonecrosis of the femoral head (ONFH ) is a disease bone metabolism, and genetic factors are generally considered to play an important role. The purpose this study was investigate relationship between single nucleotide polymorphisms (SNPs) in MIR17HG MIR155HG risk steroid-induced ONFH population northern China.MethodsA total 199 patients 506 healthy controls were recruited for study. Four SNPs seven genotyped by Sequenom MassARRAY. ORs 95% CIs used...