A5103108344- RNA modifications and cancer
- RNA Research and Splicing
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Plant Disease Resistance and Genetics
- Pelvic floor disorders treatments
- RNA and protein synthesis mechanisms
- Circular RNAs in diseases
- Prostate Cancer Treatment and Research
- Urinary Bladder and Prostate Research
- Peptidase Inhibition and Analysis
Guilin Medical University
2023-2025
Macau University of Science and Technology
2023-2025
Second Affiliated Hospital of Harbin Medical University
2022-2024
Harbin Medical University
2022-2024
Hubei University
2023
First Affiliated Hospital of GuangXi Medical University
2022
Guangxi Medical University
2022
Background: Prostate cancer (PCa) is the second most prevalent in males globally, impacting one out of every six males. However, therapeutic effect chemotherapy on PCa restricted. Methods: To address this, we developed a tumor-targeted multifunctional liposomal platform (PTX-PS/Zn@Lip-Apt) for zinc-enhanced chemo-photodynamic therapy PCa. Co-delivery PTX and an aggregation-induced emission photosensitizer (TPEDPD) enables combined photody-namic therapy. Zinc ions were loaded into liposomes...
Abstract Transcriptome analysis based on high-throughput sequencing of a cDNA library has been widely applied to functional genomic studies. However, the dependence most RNA techniques constrains their ability detect base modifications RNA, which is an important element for post-transcriptional regulation gene expression. To comprehensively profile N 6 -methyladenosine (m6A) and 5 -methylcytosine (m5C) direct (DRS) using latest Oxford Nanopore Technology was analyze transcriptome six tissues...
Colorectal cancer is the third most common cause of death among cancers in world. Although improvements various treatments have greatly improved survival time colorectal patients, since often at an advanced stage when diagnosed, prognosis patients still very poor. Since ceRNA regulatory network was proposed 2011, it has promoted study molecular mechanism occurrence and development.Exploring new development providing targets for diagnosis treatment cancer.We analyzed RNA-seq data CRC from...
Background: Failure to standardize bladder volume in the evaluation of stress urinary incontinence (SUI) may be a contributing factor controversy surrounding diagnostic and prognostic efficacy urodynamic studies (UDS) female patients with SUI. This study was conducted explore effects on urethral mobility SUI under increased intra-abdominal pressure. Methods: prospective enrolled uncomplicated admitted Second Affiliated Hospital Guilin Medical University Shaoyang Central Hospital, between...