A5046914694- Metal complexes synthesis and properties
- Magnetism in coordination complexes
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Organometallic Complex Synthesis and Catalysis
- Inorganic and Organometallic Chemistry
- Thermal and Kinetic Analysis
- Crystal structures of chemical compounds
- Crystallography and molecular interactions
- Organometallic Compounds Synthesis and Characterization
- Synthesis and Characterization of Heterocyclic Compounds
- Metal-Organic Frameworks: Synthesis and Applications
- Synthesis and biological activity
- Lanthanide and Transition Metal Complexes
- Click Chemistry and Applications
- Chemical Thermodynamics and Molecular Structure
- Ferrocene Chemistry and Applications
- Synthesis and Biological Evaluation
- Synthesis of Tetrazole Derivatives
- Carbon dioxide utilization in catalysis
- Asymmetric Hydrogenation and Catalysis
- Porphyrin and Phthalocyanine Chemistry
- Supramolecular Chemistry and Complexes
- Synthesis and Reactivity of Heterocycles
- Cancer therapeutics and mechanisms
Universidade Estadual Paulista (Unesp)
2013-2022
Centro Universitário de Araraquara
2010-2020
Instituto de Tecnología Química
2016
Kyoto University Research Reactor Institute
2009
The University of Tokyo
2009
Instituto de Botânica
2008
Fuzhou University
2005
Universidade Católica de Brasília
2002
Universidade de São Paulo
2002
Universidade de Marília
1997
Tuberculosis (TB) is an infectious disease caused mainly by the bacillus Mycobacterium tuberculosis (Mtb), presenting 9.5 million new cases and 1.5 deaths in 2014. The aim of this study was to evaluate a nanostructured lipid system (NLS) composed 10% phase oil (cholesterol), surfactant (soy phosphatidylcholine, sodium oleate), Eumulgin(®) HRE 40 ([castor polyoxyl-40-hydrogenated] proportion 3:6:8), 80% aqueous (phosphate buffer pH = 7.4) as tactic enhance vitro anti-Mtb activity copper(II)...
ABSTRACT Leishmaniasis is a disease found throughout the (sub)tropical parts of world caused by protozoan parasites Leishmania genus. Despite numerous problems associated with existing treatments, pharmaceutical companies continue to neglect development better ones. The high toxicity current drugs combined emerging resistance makes discovery new therapeutic alternatives urgent. We report here evaluation binuclear cyclopalladated complex containing Pd(II) and N , ′-dimethylbenzylamine (Hdmba)...
SYNTHESIS AND CYTOTOXICITY OF SOME CYCLOMETALLATED PALLADIUM(II) COM-PLEXES CONTAINING COORDINATED AZIDE DIPHOSPHINES. Some cyclopalladated compounds containing the azido group ligand and (C-N) ring of N,N-dimethylbenzylamine have been prepared by bridge opening reactions dimmer azide complex precursor with some diphosphines in different stoichiometric quantities.The neutral or ionic, mono binuclear complexes synthesized were characterized elemental analyses, I. R. spectroscopy NMR...
Antonio C. Moroa, Ana Urbaczekb, Eduardo T. De Almeidac, Fernando R. Pavand, Clarice Q.F. Leited, Adelino V.G. Nettoa & E. Mauroa* a Departamento de Química Geral e Inorgânica , Instituto Química, UNESP CEP 14801-970, Araraquara SP Brazil b Análises Clínicas, Faculdade Ciências Farmacêuticas 14801-902, c Exatas UNIFAL 31130-000, Alfenas MG d Biológicas, 14800-900,
Abstract Complexes of the type [PdX(PPh 3 )( 1 )]X [ = 4‐phenyl‐3‐thiosemicarbazide; X Cl – ( 2 ), Br I 4 and SCN 5 )] have been synthesized characterized by elemental analyses IR, UV/Vis, H 13 C NMR spectroscopy. The molecular structure complex was determined single‐crystal X‐ray diffraction. binding complexes with a purine base (guanosine) investigated spectroscopy mass spectrometry, which showed to coordinate guanosine through N7. A gel electrophoresis assay demonstrated ability cleave...
The present study describes the antiprotozoal activities of four cyclopalladated compounds, [Pd(dmba)(μ-Cl)] 2 , [Pd(dmba)(NCO)(isn)], [Pd(dmba)(N 3 )(isn)] and [Pd(dmba)(μ-NCO)] (dmba: N,N'-dimethylbenzylamine isn: isonicotinamide), against diseases leishmaniasis (Leishmania amazonensis Leishmania infantum), Chagas disease (Trypanosoma cruzi) human African trypanosomiasis brucei).[Pd(dmba)(μ-NCO)] exhibited good leishmanicidal trypanocidal L. T. cruzi intracellular amastigote forms, with a...
The aim of this study was to construct a nanostructured lipid system as strategy improve the in vitro antibacterial activity copper(II) complexes. New compounds with general formulae [CuX2(INH)2]·nH2O (X = Cl− and n 1 (1); X NCS− 5 (2); NCO− 4 (3); INH isoniazid, drug widely used treat tuberculosis) derived from reaction between chloride isoniazid presence or absence pseudohalide ions (NCS− NCO−) were synthesized characterized by infrared spectrometry, electronic absorption spectroscopy,...