A5039950242- Plant Micronutrient Interactions and Effects
- Abdominal Surgery and Complications
- Sexual function and dysfunction studies
- MicroRNA in disease regulation
- Muscle and Compartmental Disorders
- Liver Disease Diagnosis and Treatment
- Electrolyte and hormonal disorders
- Antimicrobial agents and applications
- Trace Elements in Health
- Adipokines, Inflammation, and Metabolic Diseases
- Innovative Microfluidic and Catalytic Techniques Innovation
- Cancer Mechanisms and Therapy
- Pancreatic and Hepatic Oncology Research
- Estrogen and related hormone effects
- Vasculitis and related conditions
- Autoimmune Bullous Skin Diseases
- Autophagy in Disease and Therapy
- Advanced Polymer Synthesis and Characterization
- Vascular anomalies and interventions
- Fibroblast Growth Factor Research
- Pancreatic function and diabetes
- Nitrogen and Sulfur Effects on Brassica
- Nanoparticle-Based Drug Delivery
- Cancer Treatment and Pharmacology
- Pneumothorax, Barotrauma, Emphysema
Bağcılar Eğitim ve Araştırma Hastanesi
2025
Ege University
2020-2023
Izmir University
2020
Dokuz Eylül University
2017
Manisa Celal Bayar University
2012-2016
State Hospital
2013
Abdominal compartment syndrome (ACS) is a severe clinical condition caused by in-tra-abdominal hypertension (IAH), often observed in surgical and trauma patients. However, ACS can also develop non-surgical patients with massive ascites, leading to acute kidney injury (AKI) due renal hypoperfusion. This study investigates the association between intra-abdominal pressure (IAP) changes, biomarkers, mortality ACS-related AKI. A prospective cohort was conducted on 24 hospitalized asci-tes...
Background and Objectives: Abdominal compartment syndrome (ACS) is a severe clinical condition caused by intra-abdominal hypertension (IAH), often observed in surgical trauma patients. However, ACS can also develop non-surgical patients with massive ascites, leading to acute kidney injury (AKI) due renal hypoperfusion. This study investigates the association between pressure (IAP) changes, biomarkers, mortality ACS-related AKI. Materials Methods: A prospective cohort was conducted on 24...
Hepatocellular carcinoma (HCC) is strongly associated with metabolic dysregulations/deregulations and hyperglycemia a common disturbance in diseases. Hyperglycemia defined to promote epithelial mesenchymal transition (EMT) of cancer cells various cancers but its molecular contribution HCC progression aggressiveness relatively unclear. In this study, we analyzed the mechanisms behind hyperglycemia-induced EMT cell lines. Here, report that high glucose promotes through activating c-Met...
Gastroesophageal reflux disease is a risk factor for esophageal adenocarcinoma yet studies that have investigated the relationship between erosive esophagitis and usually focused on symptom-related evidence or polymorphisms. There are no epigenetic gene expression this topic. In study, we aimed to evaluate identify whether there genetic predisposition adenocarcinoma. The Human Epigenetic Chromatin Modification Enzyme RT2 ProfilerTM PCR array (PAHS-085A) was used detect of 84 key genes...
Resistin is known as a potential mediator of obesity-associated insulin resistance. The high resistin level disrupts nitric oxide (NO)-mediated relaxation which also important in erectile function. An antioxidant alkaloid, Boldine, anti-diabetic and protects endothelial functions.We aimed to investigate expression penile tissue the presence resistance (IR) effect Boldine treatment on functions metabolic syndrome (MetS) rat model.Wistar rats were randomly divided into three groups: Control,...
Epidemiyolojik ve in vitro calismalarinda bor bilesiklerinin anti karsinojenik olabilecekleri gosterilmistir. Sitogenetik yonden stabil olan hucre hatlarinda kromozom aberasyonlari, kardes kromatit degisimi gibi testlerle yapilan calismalarda borun herhangi bir genotoksik etkisi ortaya konulmamistir. Bu calismada ise farkli bilesikleri BA (borik asit), BP (boraks pentahidrat) DPD (disodyum pentaborat dekahidrat)’ 250, 500 1000µM dozlarinda uygulanmasiyla, sitogenetik olarak olmayan CCL 62...
Nickel has long been known to have a toxic effect in humans and defined as human carcinogen. However, recent studies suggested that nickel chloride (NiCl2) may also possess anticancer properties. The liver is one of the target organs for nickel, thus, present study aims evaluate NiCl2 on biological responses hepatocellular carcinoma (HCC) cell lines. Both HuH-7, well-differentiated HCC line, Mahlavu poorly differentiated were exposed NiCl2. It was determined decreased viability both lines...
The synthesis of glycopolymers by copolymerising an allyl glucosamine (AG) monomer with co-monomers methyl methacrylate (MMA), acrylonitrile (AN) and 2-hydroxyethyl (HEMA) was investigated via free-radical polymerisation 2,2-azobisisobutyronitrile (AIBN) in dimethylformamide (DMF). Three new copolymers, poly(AG-
e15057 Background: In women, breast cancer is the most commonly diagnosed and leading cause of death worldwide. Tamoxifen used drug for endocrine treatment cancer. It reduces risk recurrence from when given to estrogen-receptor-positive patients. has recently been shown that imidazoles, an antifungal drug, possess anticancer potentials, it can be a novel therapeutic in treatment. However, effects combined with imidazole tamoxifen are unknown estrogen receptor-positive cell lines. Our study...
Introduction Lab-on-a-chip (LOC) systems can present cells multiple cues that are subjected to, including gradients of cytokines and secreted proteins from neighbouring cells, biochemical mechanical interactions with the extracellular matrix, direct cell-to-cell contacts in a controllable reproducible fashion. Simulating microenvironment LOC devices is crucial to understand metastasis preference cancer especially for planning personalised therapies hepatocellular carcinoma (HCC). Material...
Objective: Resistin is an important factor in the pathogenesis of obesity-induced insulin resistance and endothelial dysfunction-mediated cardiovascular system diseases.Endothelial dysfunction one most causes erectile dysfunction.Polyphenol resveratrol has several pharmacological functions, such as preventing inducing endothelium-dependent vascular relaxation via redox regulation nitric oxide production.The present study tested hypothesis that restores endothelium-mediated responses are...
e21037 Background: There are many drugs that can be applied to the treatment of lung cancer. These therapeutics include classical chemotherapeutics, targeted against driver mutations, and immunotherapeutics. However, still, new agents required better results patients outcomes. Recently, imidazole its compounds, a type antifungal drugs, were found have antitumor efficacy in several cancer types. Its effects on non-small-cell cells yet known. This study aimed detect anti-cancer properties...