A5054258837- Characterization and Applications of Magnetic Nanoparticles
- Nanoparticle-Based Drug Delivery
- Ultrasound and Hyperthermia Applications
- Advanced MRI Techniques and Applications
- Microfluidic and Bio-sensing Technologies
- NMR spectroscopy and applications
- Iron oxide chemistry and applications
- Radiation Therapy and Dosimetry
- Nuclear Physics and Applications
- Non-Destructive Testing Techniques
- Erythrocyte Function and Pathophysiology
- Radiation Detection and Scintillator Technologies
- Medical Imaging Techniques and Applications
- Clostridium difficile and Clostridium perfringens research
- Spectroscopy Techniques in Biomedical and Chemical Research
- Nanopore and Nanochannel Transport Studies
- Nanoplatforms for cancer theranostics
- Bacterial Identification and Susceptibility Testing
- MicroRNA in disease regulation
- Streptococcal Infections and Treatments
- Magnetic properties of thin films
- Biosensors and Analytical Detection
- Electrical and Bioimpedance Tomography
Azienda Ospedaliera Santa Maria Degli Angeli
2024
University of Pavia
2017-2022
Istituto Nazionale di Fisica Nucleare, Sezione di Pavia
2019-2022
National Interuniversity Consortium of Materials Science and Technology
2019
A combination of carbon ions/photons irradiation and hyperthermia as a novel therapeutic approach for the in-vitro treatment pancreatic cancer BxPC3 cells is presented. The radiation doses used are 0-2 Gy ions 0-7 6 MV photons. Hyperthermia realized via standard heating bath, assisted by magnetic fluid (MFH) that utilizes nanoparticles (MNPs) exposed to an alternating field amplitude 19.5 mTesla frequency 109.8 kHz. Starting from 37 °C, temperature gradually increased sample kept at 42 °C 30...
Today, public health is one of the most important challenges in society. Cancer leading cause death, so early diagnosis and localized treatments that minimize side effects are a priority. Magnetic nanoparticles have shown great potential as magnetic resonance imaging contrast agents, detection tags for vitro biosensing, mediators heating hyperthermia. One critical characteristics to adjust biomedical needs each application their polymeric coating. Fatty acid coatings known contribute...
High aspect-ratio elongated nanoparticles with suitable porosity present partially controlled chemico-physical properties to obtain good heating/contrast efficiency for biomedical applications.
We present a 1H Nuclear Magnetic Resonance (NMR) relaxometry experimental investigation of two series magnetic nanoparticles, constituted maghemite core with mean diameter dTEM = 17 ± 2.5 nm and 8 0.4 nm, respectively, coated four different negative polyelectrolytes. A full structural, morpho-dimensional characterization was performed by means Transmission Electron Microscopy, Atomic Force Microscopy DC magnetometry. The magnetization curves showed that the investigated nanoparticles...
The quality of SPECT Bremsstrahlung images patients treated with Y-90 is poor, mainly because scattered radiation and collimator septa penetration. To minimize the latter effect, High Energy (HE) or Medium (ME) collimators can be used. Scatter correction not possible through methods commonly used for diagnostic radionuclides (Tc-99m, etc.) does have distinct photopeaks, but a broad spectrum energies ranging from zero to maximum one detectable by gamma-camera crystal registered. penetration...