A5025180719- Diabetes Management and Research
- Diabetes and associated disorders
- Diabetes Management and Education
- Chronic Disease Management Strategies
- Mobile Health and mHealth Applications
- Mental Health Research Topics
- Digital Mental Health Interventions
- Pancreatic function and diabetes
- Nutritional Studies and Diet
- GDF15 and Related Biomarkers
- Diabetes Treatment and Management
- Mechanical Circulatory Support Devices
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Nursing Education, Practice, and Leadership
- Impact of Technology on Adolescents
- Health and Lifestyle Studies
- Folate and B Vitamins Research
- Organic Food and Agriculture
- COVID-19 Clinical Research Studies
- Urban Agriculture and Sustainability
- Cultural Competency in Health Care
- Retinal Imaging and Analysis
- Food Security and Health in Diverse Populations
- Cancer, Hypoxia, and Metabolism
- Retinal Diseases and Treatments
Joslin Diabetes Center
2020-2025
Johns Hopkins University
2024
University of Sharjah
2024
Harvard University
2020-2021
Columbus Center
2021
Multisystem inflammatory syndrome in children (MIS-C) is a severe complication of SARS-CoV-2 infection. It remains unclear how MIS-C phenotypes vary across variants. We aimed to investigate clinical characteristics and outcomes eras.
BACKGROUND. We aimed to characterize factors associated with the under-studied complication of cognitive decline in aging people long-duration type 1 diabetes (T1D).
The COVID-19 pandemic pushed millions of Americans into food insecurity. Food policy councils (FPCs) across the country played a vital role in organizing coordinated responses multiple sectors. We used social network analysis (SNA) approach to investigate: (1) partnering organizations and agencies within FPCs; (2) how characteristics FPCs' partnerships (i.e., degree, coreness, density) related programmatic, policy, advocacy actions response pandemic; (3) use racial or equity framework...
OBJECTIVE Continuous glucose monitoring (CGM) use in older adults with type 1 diabetes (T1D) has shown benefits. However, the impact of CGM use, coupled simplified treatment regimens and personalized glycemic goals that are better suited for patients multiple comorbidities hypoglycemia, is not known. RESEARCH DESIGN AND METHODS Older (≥65 years) T1D hypoglycemia (two or more episodes [blood <70 mg/dL ≥20 min over 2 weeks]) who were naïve users randomized to intervention control...
Cognitive dysfunction is a growing and understudied public health issue in the aging type 1 diabetic population difficult time-consuming to diagnose. Studies long duration diabetes have reported presence of proliferative retinopathy was associated with cognitive dysfunction.
OBJECTIVE Adults with type 1 diabetes (T1D) are aging successfully. The impact of duration on clinical and functional status as people age T1D is not well known. RESEARCH DESIGN AND METHODS We performed a cross-sectional study older adults (age ≥65 years) T1D. RESULTS evaluated 165 adults, mean 70 ± 10 years. After adjustment for age, sex, A1C, longer T1D, ≥50 years, was associated higher likelihood depression (odds ratio [OR] 2.8; P = 0.008), hypoglycemia unawareness (OR 2.6; 0.01), lower...
Objective:Older adults are generally less proficient in technology use compared with younger adults. Data on telemedicine during the COVID-19 pandemic older persons type 1 diabetes (T1D) and association of diabetes-related limited. We evaluated care delivery to T1D a prepandemic period.Methods:Data from electronic health records were for visit types (in-person, phone, video) two sequential 12-month intervals: (April 2019-March 2020) 2020-March 2021).Results:Data 2,832 unique age cohorts:...
OBJECTIVE To assess the relationship between glucose management indicator (GMI) and HbA1c in non-White individuals with diabetes. RESEARCH DESIGN AND METHODS We performed a retrospective analysis of continuous monitoring metrics diabetes divided by race into White cohorts. RESULTS evaluated 316 (non-White n = 68; 248). Although GMI was not different (7.6 vs. 7.7; P significant) cohorts, higher cohort (8.7% 8.1%; 0.004). than ≥0.5% more frequently observed (90% 75%; 0.02). In only, duration...
Abstract Objective Integrating electronic health record (EHR) data with other resources is essential in rare disease research due to low prevalence. Such integration dependent on the alignment of ontologies used for annotation. The international classification diseases (ICD) annotate clinical diagnoses, while human phenotype ontology (HPO) phenotypes. Although these overlap biomedical entities they describe, extent which are interoperable unknown. We investigate how well aligned and whether...
Even though 1 in 5 Americans experience some form of mental illness each year, 80% have been shown to discontinue psychotherapy prematurely. The traditional service delivery model, consisting isolated clinical sessions, lacks the ability keep patients engaged outside sessions. Newer digital health platforms can address need for a robust tool that tracks well-being and improves engagement with depressive symptoms.The primary goals this feasibility study were (1) assess compliance among...
<p dir="ltr">Objective: Continuous Glucose Monitoring (CGM) use in older adults with Type-1 Diabetes (T1D) has shown benefits. However, the impact of CGM use, coupled simplified treatment regimens and personalized glycemic goals that are better suited for patients multiple comorbidities hypoglycemia, is not known.</p><p><br></p><p dir="ltr">Research Design Methods: Older (≥65 years) T1D hypoglycemia (≥2 episodes <70 mg/dL ≥20 minutes over 2 weeks) who...
<p dir="ltr">Objective: Continuous Glucose Monitoring (CGM) use in older adults with Type-1 Diabetes (T1D) has shown benefits. However, the impact of CGM use, coupled simplified treatment regimens and personalized glycemic goals that are better suited for patients multiple comorbidities hypoglycemia, is not known.</p><p><br></p><p dir="ltr">Research Design Methods: Older (≥65 years) T1D hypoglycemia (≥2 episodes <70 mg/dL ≥20 minutes over 2 weeks) who...
Aims: To evaluate the use of hybrid (telehealth and in-person) care on visitation glycaemia in older adults with type 1 diabetes (T1D). Methods: In this retrospective study, we examined clinical characteristics, number visits continuous glucose monitoring (CGM) metrics for (≥65 years) T1D from electronic health records during pre-COVID-19 pandemic (March 1, 2019-March 2020; (September 2020-August 31, 2021; hybrid) periods. Main outcomes were changes glycaemic control (HbA1c), a sub-group...
Cognitive impairment, micro and macrovascular complications contribute to the high morbidity mortality of type 1 diabetes (T1D) in an aging population. The dietary inflammatory index (DII), a validated measure potential nutrients, has not been evaluated for its relationship T1D. To this end, semiquantitative food frequency questionnaires were administered at baseline 591 individuals Joslin 50-year Medalist Study (“Medalists”), well-characterized cohort having ≥50 years DII score was derived...
<sec> <title>BACKGROUND</title> Even though 1 in 5 Americans experience some form of mental illness each year, 80% have been shown to discontinue psychotherapy prematurely. The traditional service delivery model, consisting isolated clinical sessions, lacks the ability keep patients engaged outside sessions. Newer digital health platforms can address need for a robust tool that tracks well-being and improves engagement with depressive symptoms. </sec> <title>OBJECTIVE</title> primary goals...
Cultural and language barriers are known to reduce the likelihood of Asian-American patients (AA) with diabetes achieving recommended goals for HbA1c, blood pressure, LDL, as ‘ABCs DM.’ Our previous study an integrated Asian clinic AA (AAC) at Joslin Diabetes Center, showed more ABC 1-year after their initial visit, than whites in Adult (WDC). AAC staff, including MDs, dietitians, educators, patient coordinators, all multi-lingual AAs who offer culturally-tailored management approaches. In a...
Over the pandemic, little is known on extent to which in-person visits (IP) have been reduced and replaced with telehealth in patients type 1 diabetes (T1D). In this study, we reviewed aging T1D (65 years older) seen IP, phone (PV), video (VV) at Joslin Diabetes Center from March September 2020, 2019, 2018. 7-month period, 3,276 clinical were attended 2018, 2,980 2,565 2020. The number of IP decreased by 88.89% same periods, PV VV increased 4 0 respectively 2018 1,338 602 each 2020 (>1000%)....
Patient cancellations of scheduled visits may result in missed opportunities for timely treatment and counseling adversely impact quality patient care. Identification risk factors might allow clinicians to define subgroups more likely miss interventions that prevent lapses The purpose this study was identify associated with visit patients followed at a tertiary care referral center diabetes eye A retrospective review the Joslin Diabetes Center’s Beetham Eye Institute electronic medical...
Cardiovascular disease (CVD) is a major cause of mortality in long-duration type 1 diabetes (T1D) despite the absence nephropathy (DN). However, its mechanisms are incompletely understood. Joslin 50-Year “Medalists”, with T1D≥50 years, ideal for studying CVD renoprotected T1D cohort, as only 13% have DN, yet 40% CVD. A Medalist subset underwent coronary artery calcification scans (CAC; n=75) and cardiac magnetic resonance (CMR; n=60) left ventricular (LV) mass volumes. In exploratory...
Diabetic nephropathy (DN) causes much morbidity and mortality in T1D, necessitating better mechanistic insights for improved prevention therapy. In addition to hyperglycemia, DN pathogenesis may involve inflammation or insulin resistance, diets modulating these pathways impact risk. this cross-sectional study, we examined associations of inflammatory insulinemic potentials whole with a subset the Joslin 50-year Medalist Study, comprising 570 individuals T1D &gt;50 years food frequency...