A5029979176- Animal Virus Infections Studies
- Virus-based gene therapy research
- Viral gastroenteritis research and epidemiology
- Viral Infections and Immunology Research
- Animal Disease Management and Epidemiology
- HIV Research and Treatment
- Virology and Viral Diseases
- Veterinary Oncology Research
- RNA Interference and Gene Delivery
- Respiratory viral infections research
- T-cell and Retrovirus Studies
- Vector-Borne Animal Diseases
- interferon and immune responses
- Hepatitis B Virus Studies
- Herpesvirus Infections and Treatments
- Influenza Virus Research Studies
- Cancer Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Cervical Cancer and HPV Research
- Inflammatory Myopathies and Dermatomyositis
- SARS-CoV-2 and COVID-19 Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Skin Diseases and Diabetes
- Mosquito-borne diseases and control
University of Veterinary Medicine
2018-2025
University of Minnesota
2020
Iuliu Hațieganu University of Medicine and Pharmacy
2006
More than 20 years after the first outbreaks, phylogenetic picture of PRRSV is still incomplete and full gaps, especially in regards 1. Due to exceptional diversity observed at eastern borders Europe low number available sequences from Central Eastern European countries, authors collected analyzed both recent as well already submitted comparing them a large backbone set ORF5 representing spectrum 1 Subtype conduct systematic analysis reclassification elucidating virus these countries....
Abstract Background Atypical porcine pestivirus (APPeV), also known as Pestivirus scrofae , is a member of the genus within Flaviviridae family. Experimental infections have directly linked APPeV to congenital tremor (CT) type A-II in congenitally infected piglets born challenged sows. Here, we report assessment prevalence Hungarian pig herds and influence different sample types on detection rates. Results Altogether, 2650 blood serum, 198 oral fluid 163 processing samples were obtained via...
A szerzők szakirodalmi adatok és saját eredményeik alapján összefoglalják a sertéscircovírusokkal kapcsolatos legfontosabb ismereteket. Míg PCV1 általánosan apatogénnek tekinthető, PCV2 jelentős gazdasági károkat okozó, endémiásan keringő vírus sertésállományokban, amelyet az általa okozott szisztémás, sorvadásos megbetegedés kapcsán azonosítottak. PCV3 járványtani jelentősége még vitatott, de feltehetőleg szaporodásbiológia zavarokat szisztémás megbetegedést okozhat. PCV4-et nemrégiben...
The H9N2 subtype of low-pathogenic avian influenza viruses (LPAIV) is a widespread pathogen poultry that can also infect humans. characterization viral infections complex process, involving clinical, pathological, and virological investigations. aim this study was to adapt optimize an immunohistochemical (IHC) technique developed for LPAIVs specifically the detection virus antigens in infected tissues. Twenty-one-day-old broiler chickens were inoculated with three different strains by...
Atypical porcine pestivirus (APPV) is a recently identified RNA virus within the Flaviviridae family, causing congenital tremor (CT) in piglets of infected sows. We have investigated 25 cases CT from 2005, 2007, 2010 and 2016–2018, originating six different farms. RT-PCR has been performed on these samples all affected were positive to APPV. Our phylogenetic analysis showed that Hungarian strains show high degree variability are clustered into five distinct lineages. Four one farm shown...
In the last few decades, many new paramyxoviruses have been discovered, causing diverse, mostly respiratory diseases in animals and humans. The porcine parainfluenza virus 1 (PPIV-1, species Porcine respirovirus 1), which has reported countries worldwide, was found both healthy clinically ill pigs showing signs. Here, we report expected prevalence genetic diversity of PPIV-1 Hungarian pig herds detection one Slovakian farm, is first evidence for presence country. To estimate Hungary 211 oral...
Porcine respirovirus 1 (PRV1) is also known as porcine parainfluenza virus (PPIV1). The prevalence and the role of PRV1 infections for pig health largely unknown. In order to assess in Poland, nasal swabs oral fluids collected from pigs 30 farms were examined with RT real-time PCR. Additionally, IAV PRRSV infection statuses PRV1-positive samples examined. results showed that highly prevalent (76.7% positive) different patterns circulation herds mild-moderate respiratory disease observed....
Porcine respirovirus 1, also known as parainfluenza virus 1 (PPIV-1) was first identified in Hong Kong 2013, later the USA and most recently Chile. Here, we report detection of PPIV-1 outside these three regions. We screened 22 farms Hungary by testing 15 nasal swab samples obtained from 3-week-old piglets (3 randomly chosen 5 litters each farm). Only one farm found to be positive. subsequently sampled positive taking cross-sectional 20 2-, 4-, 6- 8-week-old piglets. Virus qRT-PCR showed...
Swine viral diseases have the capacity to cause significant losses and affect sector’s sustainability, a situation further exacerbated by lack of antiviral drugs limited availability effective vaccines. In this context, novel point-of-care (POC) diagnostic device incorporating photonic integrated circuits (PICs), microfluidics information, communication technology into single platform was developed for field diagnosis African swine fever (ASF) classical (CSF). The targets particles has been...
Porcine parvovirus 8 (PPV8), a novel virus in the Parvoviridae family, was first identified 2022 lung samples of domestic pigs from China. Retrospective analyses showed that it had been circulating China since 1998, but no other countries reported its presence so far. A recent study conducted South America did not detect any PPV8-positive region. Here we report detection PPV8 Hungarian and Slovakian pig farms estimated prevalence Hungary. Altogether 2230 serum, 233 oral fluid, 115 processing...
Porcine parvovirus 8 (PPV8), a novel virus in the Parvoviridae family, was first identified 2022 lung samples of domestic pigs from China. Retrospective analyses showed that it had been circulating China since 1998, but no other countries reported its presence so far. A recent study conducted South America did not detect any PPV8-positive region. Here, we report detection PPV8 Hungarian and Slovakian pig farms estimated prevalence Hungary. Altogether, 2230 serum, 233 oral fluid, 115...
Porcine circovirus type 3 (PCV3) is an emerging pathogen that has been reported worldwide in all ages of healthy and clinically ill pigs. The presence this virus Hungary confirmed a commercial farm experiencing reproductive failures, but there were no data on the circulation PCV3 country. Here we report prevalence genetic diversity Hungarian herds. To estimate prevalence, 1855 serum samples, 176 oral fluid 97 processing samples collected systematic, cross-sectional method from 20 large scale...
In this paper we present the development of photonic integrated circuit (PIC) biosensors for label-free detection six emerging and endemic swine viruses, namely: African Swine Fever Virus (ASFV), Classical (CSFV), Porcine Reproductive Respiratory Syndrome (PPRSV), Parvovirus (PPV), Circovirus 2 (PCV2), Influenza A (SIV). The optical are based on evanescent wave technology and, in particular, Resonant Rings (RRs) fabricated silicon nitride. novel were packaged an sensing cartridge that...
Objectives Feline immunodeficiency virus (FIV) and feline leukaemia (FeLV) are retroviruses affecting cats worldwide. The objectives of the study were to estimate prevalence these in domestic Hungary characterise phylogenetic relationships FIV strains. Methods A total 335 anticoagulated whole-blood samples obtained from both a healthy ill cat population examined for presence FeLV with two methods: ELISA PCR. Statistical analysis was carried out analyse data obtained. Sequencing partial...
Feline immunodeficiency virus (FIV) and feline leukaemia (FeLV) are retroviruses affecting felid species worldwide. A study was performed over a period of 5 months in Ireland with the aim to get an updated more realistic prevalence these retroviruses. total 183 EDTA-anticoagulated whole-blood samples were collected from cats distributed between 10 clinics. The tested using both point-of-care enzyme-linked immunosorbent assay (ELISA) polymerase chain reaction (PCR). Basic clinical data...
In this paper, we present the concept of a novel diagnostic device for on-site analyses, based on use advanced bio-sensing and photonics technologies to tackle emerging endemic viruses causing swine epidemics significant economic damage in farms. The is currently under development framework EU Commission co-funded project. overall behind project develop method an early fast field detection selected by non-specialized personnel. technology able detect pathogens different types biological...
Atypical porcine pestivirus (APPV) belongs to the genus Pestivirus within family Flaviviridae. Recently, APPV has been identified as causative agent of congenital tremor (CT) type AII. The disease is a neurological disorder that affects newborn piglets and characterized by generalized trembling animals often splay legs. CT well known worldwide, virus seems be highly prevalent in major swine producing areas. However, little about epidemiology infection, transmission spread between herds....
An 8-y-old castrated male, outdoor European shorthair cat was presented with a history of hindlimb weakness and paralysis. Disease progression continuous from the onset; deep algesia disappeared at final stage. Radiography vertebral column unremarkable; along patient physical examination results, magnetic resonance imaging suggested inflammatory lesions in spinal cord, although neoplasia could not be ruled out. Feline leukemia virus (FeLV) positivity confirmed by serum ELISA prior to...
Osteochondromatosis, also known as multiple cartilaginous exostosis, polyostotic osteochondroma, and osteochondromas, comprises one-fifth of all primary bone tumors in cats, with no breed or sex predisposition hereditary pattern. Unlike dogs, horses, humans, it is predominantly seen young cats (2-4 years old), after the maturation skeleton. Although pathogenesis osteochondromatosis not fully understood, considered to be related infection by feline leukemia virus (FeLV) other retroviruses,...
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To date, seven novel parvoviruses have been identified in pigs and designated as porcine parvovirus 2–7 (PPV2–7). The presence of these emerging viruses has reported several countries around the world, although their pathogenic role clinical economical relevance are largely unknown. Here, we report estimated prevalence genetic diversity PPV2–7 Hungarian pig herds detection two Slovakian farms. For comparative estimation, 2505 serum samples from different age groups, 218 oral fluid samples,...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide since its emergence and is causing the disease COVID-19. According to WHO, this a zoonotic disease. Several cases have already been discovered where companion animals were affected due virus spillover from humans, however, symptoms are mild in most cases. We report first documented case of SARS-CoV-2 infection death domestic cat (Felis silvestris catus) Hungary, no other could be detected.
Our study aimed to investigate the virulence of three recent H9N2 LPAIV strains belonging G1 lineage, isolated from field infections in North Africa and Middle East. Three-week-old commercial broiler chickens (in total 62) were included randomly allocated into infected test groups one control group. Each group was inoculated intranasally/intratracheally with isolates at a dose 108 EID50 virus. The received phosphate-buffered saline (PBS) via same route application. pathogenicity evaluated...