A5009432661- Cystic Fibrosis Research Advances
- Bacterial biofilms and quorum sensing
- Infections and bacterial resistance
- Respiratory and Cough-Related Research
- Neonatal Respiratory Health Research
- Gut microbiota and health
- Respiratory viral infections research
- Pediatric health and respiratory diseases
- Antibiotic Resistance in Bacteria
- Orthopedic Infections and Treatments
- Mycobacterium research and diagnosis
- Streptococcal Infections and Treatments
- Parasitic infections in humans and animals
- Nail Diseases and Treatments
- Plant Pathogenic Bacteria Studies
- Antimicrobial Resistance in Staphylococcus
- Antibiotic Use and Resistance
- Gastrointestinal motility and disorders
- Wound Healing and Treatments
- Intramuscular injections and effects
- Clostridium difficile and Clostridium perfringens research
- Ear Surgery and Otitis Media
- Leech Biology and Applications
- Infective Endocarditis Diagnosis and Management
- Diphtheria, Corynebacterium, and Tetanus
Russian Children's Clinical Hospital
2019-2024
City Clinical Hospital
2019-2024
Chronic lower respiratory tract infection in patients with cystic fibrosis (CF) is the major factor determining severity of clinical course and prognosis disease. The purpose study was to investigate prevailing microflora CF changes activity antibacterial medicines (ABM) during period 2000–2015 order optimize guidelines for antibiotic therapy. Bronchial secretion evaluated from 2000 till 2015. 9774 samples were studied, 16.703 microbial strains obtained. In 2000–2015, P. aeruginosa (smooth...
Stenotrophomonas maltophilia is a common opportunistic microorganism and an important respiratory pathogen in cystic fibrosis (CF). The aim of this study was to determine antimicrobial resistance phenotypes, sequence-types (ST) genetic determinants antibiotic S. strains recovered from CF patients Russia. isolates 170 were analyzed. Minimum inhibitory concentrations antibacterial agents determined using Sensititre Gram Negative GNX2F plates the results interpreted according Clinical...
Cystic fibrosis (CF) is a common genetic disease, manifested by airway obstruction and chronic respiratory infection. The most prevalent infectious agent in airways of CF patients Pseudomonas aeruginosa. This study aimed to determine sequence-types, antimicrobial resistance phenotypes genes defining adaptive antibiotic P. aeruginosa isolates recovered from Russia. In total, 84 strains 64 were analyzed. Susceptibility antibiotics was determined disk diffusion test. Whole-genome sequencing...
Background. One of the complications in patients hospitalized with COVID-19 is a secondary bacterial infection. Its frequency can reach 15%, which makes it important to determine etiology and antimicrobial resistance key pathogens responsible for development this pathology, order further improve practice prescribing increase effectiveness chemotherapy. Aims assess etiological structure antibiotic main SBIs prescription. Methods. This retrospective study reviewed medical records Moscow city...
Fecal microbiota transplantation (FMT) is a promising therapy for variety of diseases involving the gastrointestinal (GI) tract. The purpose our study to evaluate effectiveness FMT treatment different GI complications after allogenic hematopoietic stem cell (steroid-refractory and steroid-dependent graft versus host disease (SR/ SD GVHD) infectious enterocolitis) in children from 1.5 18 years old. was approved by Local Ethics Committee Morozov Children's Clinical Hospital Department Health...
Background. Primary ciliary dyskinesia (PCD) is an orphan disease, and diagnosis difficult because there no gold standard for diagnosis. Aim. Clinical, laboratory-instrumental, genetic characteristics of PCD in children. Materials methods. From 2009 to 2024, 31 patients with a genetically confirmed were observed as part multicenter, open-ended, descriptive pilot longitudinal study. Examination methods: clinical anamnestic method; X-ray examination computed tomography the chest organs...
Background. Primary ciliary dyskinesia (PCD) is an orphan disease, and diagnosis difficult because there no gold standard for diagnosis. Aim. Clinical, laboratory-instrumental, genetic characteristics of PCD in children. Materials methods. From 2009 to 2024, 31 patients with a genetically confirmed were observed as part multicenter, open-ended, descriptive pilot longitudinal study. Examination methods: clinical anamnestic method; X-ray examination computed tomography the chest organs...
Детская Городская Больница Святой Ольги,
<h3>ЦЕЛЬ ИССЛЕДОВАНИЯ</h3> Изучить спектр бактериальных патогенов, вызывающих острый гнойный средний отит (ОГСО) у детей Московского региона в современных условиях и оценить их чувствительность к основным группам антибиотиков. <h3>МАТЕРИАЛ И МЕТОДЫ</h3> В исследование включены 1864 ребенка, прошедших обследование получивших лечение оториноларингологическом отделении ГБУЗ «Морозовская ДГКБ ДЗМ» период с 01.07.18 по 31.06.20 диагнозом ОГСО. <h3>РЕЗУЛЬТАТЫ</h3> Исследование показало, что...
Cysticercosis is a preventable parasitic infection caused by the cestode (tapeworm) Taenia solium. In several countries of Africa, Asia, and Latin America, cysticercosis endemic. developed countries, predominantly an imported disease or associated with poor regions deprived sanitary resources. We present case 94-year-old Spanish woman who was admitted to emergency room due right leg trauma, edema, superfi cial venous dilation same extremity. The patient came from rural remote area. With...
To study current spectrum of bacterial pathogens that cause exacerbation chronic suppurative otitis media (CSOM) in children, who live Moscow region, and to investigate sensitivity isolated strains various antibacterial drugs.
Objective. To determine species, sequence-types, antimicrobial resistance and virulence genes in Achromobacter spp. isolates obtained from cystic fibrosis (CF) patients Russia. Materials Methods. Samples (sputum, nasopharyngeal swab) 168 CF 48 regions were studied. Whole-genome sequencing (WGS) was performed on MGISEQ-2000 platform. SPAdes software, Galaxy, ResFinder, Integrall, PubMLST used for analysis of WGS data. Results. A total 18 strains isolated 16 patients.Achromobacter xylosoxidans...