A5066633144- Dialysis and Renal Disease Management
- Medication Adherence and Compliance
- Iron Metabolism and Disorders
- Health Systems, Economic Evaluations, Quality of Life
- Frailty in Older Adults
- Erythropoietin and Anemia Treatment
- Potassium and Related Disorders
- Patient-Provider Communication in Healthcare
- Magnesium in Health and Disease
- Renal Diseases and Glomerulopathies
- Pharmaceutical Practices and Patient Outcomes
- Acute Ischemic Stroke Management
- Chronic Kidney Disease and Diabetes
- Pharmaceutical studies and practices
- Blood Pressure and Hypertension Studies
- Pharmacological Effects and Toxicity Studies
- Health Literacy and Information Accessibility
- Heart Failure Treatment and Management
- Vaccine Coverage and Hesitancy
- Systemic Sclerosis and Related Diseases
- COVID-19 and Mental Health
- Cardiac Imaging and Diagnostics
- Hemoglobinopathies and Related Disorders
- Cardiovascular Function and Risk Factors
- Atrial Fibrillation Management and Outcomes
Fukushima Medical University
2023-2024
Kyushu University of Health and Welfare
2023-2024
Kyushu University
2024
Kyushu Nutrition Welfare University
2023
University of Miyazaki
2014-2021
Miyazaki Prefectural Hospital
2017-2020
V.I.Shumakov Federal Research Center of Transplantology and Artificial Organs
2016
University of Miyazaki Hospital
2013
Abstract In patients undergoing hemodialysis, the impact of atrial fibrillation (AF) through cardiac thromboembolism on development ischemic stroke may be influenced by severity atherosclerosis present. However, there are no large-scale reports confirming whether influences relationship between AF and in requiring hemodialysis. We aimed to investigate effects atherosclerotic disease new-onset stroke. This nationwide longitudinal study based dialysis facilities across Japan used data...
Rationale & Objective Person-centered care (PCC) and trust in physicians influence medication adherence (MA) among patients undergoing dialysis. However, the mechanisms linking PCC to MA, particularly mediating effect of physicians, remain unclear. This study aimed investigate interrelationships between PCC, MA. Study Design Multicenter cross-sectional study. Setting Participants Japanese adults receiving outpatient hemodialysis at six dialysis centers. Exposures was assessed using...
Background: Shared decision-making (SDM) is a key process in selecting renal replacement therapy (RRT). This study analyzed SDM perceptions, preferences, and patient- facility-level factors influencing among Japanese patients with chronic kidney disease (CKD) who selected RRT. Methods: We 475 adult CKD from 49 medical facilities. awareness recognition, preferences for timing frequency, discussion content, desired professional involvement were assessed. Patient- associated perceptions...
Background and objectives In dialysis patients, the associations between apoprotein profile all-cause or cardiovascular disease (CVD)-related mortality are not well known. We, therefore, investigated whether levels associated with these events. Design, setting, participants, & measurements We undertook a prospective observational cohort study of prevalent hemodialysis patients aged ≥18 years ( n =1081), who were followed for 4 (2011–2014). Outcomes CVD-related mortality. Predictors used...
Coronavirus disease-2019 (COVID-19) has affected more than 220 million individuals since the global pandemic began. There is an urgent need for safe and effective vaccines, vaccinations, such as mRNA have been initiated worldwide. However, adverse effects of these vaccines remain unclear. We herein present a case 80-year-old female on maintenance hemodialysis who developed takotsubo cardiomyopathy 4 days after receiving first dose Pfizer-BioNTech COVID-19 vaccine. was no obvious trigger...
N-terminal-pro-B-type-natriuretic peptide (NT-proBNP) was a predictive marker of cardiovascular disease (CVD)-related death in chronic dialysis patients. NT-proBNP also correlated with markers inflammation, malnutrition and protein-energy wasting. We hypothesized whether associated non-CVD A prospective observational study for incidence patients conducted. Prevalent (n = 1310) were enrolled followed 24 months. One hundred forty-four deaths recorded. Area under the curve using ROC analysis...
Left ventricular diastolic dysfunction (LVDD) causes heart failure with a preserved left ejection fraction (LVEF) in the general population.To examine relationships between LVDD grades of 2016 American Society Echocardiography/European Association Cardiovascular Imaging (ASE/EACVI) recommendations and several arteriosclerotic parameters major cardiovascular events (MACE) hemodialysis patients LVEF.Sixty-three prevalent (median age [interquartile range], 69 [64-75] years, 31.7% female) normal...
Lanthanum carbonate (LC) is a non-calcium-containing phosphate binder and shows comparable effect with other binders on hyperphosphatemia in dialysis patients. LC also contributes to reduced oral calcium load compared (CaC) treatment. However, no crossover studies which compare the influence serum level between treatments CaC hemodialysis (HD) patients have been carried out.After washout for 2 weeks, 50 HD were randomized (1 : 1) receive or 3 months. Thereafter, underwent second 2-week...
Background Basic health literacy and trust in physicians can influence medication adherence patients receiving dialysis. However, how high-order is associated with mediates this association remain unclear. We assessed the inter-relationships between literacy, physicians, adherence. investigated mediating role of relationship Methods This multicenter cross-sectional study included Japanese adults outpatient hemodialysis at six dialysis centers. Multidimensional was measured using 14-item...
<b><i>Background/Aims: </i></b>Predictors including the preventive effects of antiplatelet and anticoagulant drugs on cerebral infarction (CI) events have not yet been clarified in dialysis patients. The aim present study was to examine risk CI these Japanese hemodialysis <b><i>Methods: </i></b>Patients receiving maintenance (n=1,551, median age (interquartile range), 69.0 (59.0-78.0) years; 41.5% female) were enrolled Miyazaki Dialysis Cohort...
Background Although hemoglobin (Hb) levels are affected by a change in the body fluid status, relationship between Hb and mortality while taking interdialytic weight gain (IDWG) at blood sampling into account has not yet been examined hemodialysis patients. Study design Cohort study. Setting, Participants Data from Miyazaki Dialysis cohort study, including 1375 prevalent patients (median age (interquartile range), 69 (60–77) years, 42.3% female). Predictor Patients were divided 5 categories...
Iron deficiency/excess may be associated with worse prognosis in patients undergoing hemodialysis. This study ascertained the association of estimated total body iron (TBI) mortality receiving Multicenter clinical data collected Miyazaki Dialysis Cohort Study from 943 hemodialysis were analyzed after stratification into tertile categories by baseline TBI—estimated as heme plus storage ferritin levels. The primary outcome was a 5-year all-cause mortality; hazard ratios TBI–all-cause using Cox...
<b><i>Background/Aims:</i></b> We investigated the method of switching EPO to CERA that does not cause a decrease in Hb level. <b><i>Methods:</i></b> Fifty EPO-treated patients were randomly divided into two groups which was administered every weeks (Q2W) or four (Q4W). After 8 treatment, frequency administration changed Q4W former. Follow-up performed for 24 weeks. <b><i>Results:</i></b> There no difference level...
Background: The relationships between serum zinc levels and body composition or clinical outcomes of incident hemodialysis (HD) patients remain unclear. Methods: This prospective observational study examined the indexes, including composition, in 142 HD using a bioelectrical impedance analysis. Patients were divided into three groups according to baseline levels: tertile, <45, 45–59, ≥60 µg/dL. reference group was set as Cox’s regression analysis performed investigate categories...
How dialysis affects the survival of patients with biopsy-proven IgA nephropathy (IgAN) is not fully understood. The present long-term cohort study quantifies rates and incidence cardio-cerebrovascular diseases (CCVDs) among such in Japan.Fifty-two 433 IgAN who had reached end-stage kidney disease underwent renal replacement therapy (RRT) between 1981 2010. overall rate CCVDs these were evaluated during follow-up for 11.3 ± 6.4 years.The mean age at starting RRT was 42.8 13.3 years. Only...
We investigated the effects of bovine lactoferrin (LF) on maintenance respiratory and systemic physical conditions. A randomized, double-blind, placebo-controlled trial was conducted. Healthy adults at Kyushu University Health Welfare ingested a placebo or LF (200 mg/day) for 12 weeks. The primary endpoints were total symptom scores. secondary endpoint activity plasmacytoid dendritic cells (pDCs) in peripheral blood. 157 subjects randomized (placebo, n = 79; LF, 78), whom, dropped out....
Abstract Characterisation of N-terminal pro-brain natriuretic peptide (NT-proBNP) in chronic haemodialysis patients and its prognostic significance age stratification have not been addressed. A prospective cohort study with cross-sectional analyses at baseline was performed. Outcomes were all-cause mortality, non-malignancy-related cardiovascular disease (CVD)-related mortality. NT-proBNP significantly higher elderly, female, low dry weight patients. Study divided into two groups: Group-O...
Although infection is the second leading cause of death in maintenance haemodialysis patients, effects glycaemic control on diabetic patients have not yet been examined detail. We relationship between diabetes or glycemic and infection-related hospitalization (IRH) patients.Patients receiving (n = 1551, 493 patients) were enrolled this prospective cohort study December 2009 followed-up for 3 years. IRH during follow-up period was abstracted from medical records. Kaplan-Meier Cox regression...
Background/Aims: Uric acid (UA) levels are affected by changes in dialysis; however, the relationship between pre- and postdialysis UA difference (UAD) mortality remains unclear. Methods: A total of 1,073 patients receiving maintenance hemodialysis (HD) were enrolled this cohort study followed up for 5 years. Patients divided into quartile categories according to baseline UAD. Cox’s regression analyses used investigate UAD all-cause cardiovascular (CV) mortalities while adjusting potential...
Objectives To investigate the relationship between dry weight (DW) change and survival in long-term maintenance prevalent dialysis patients. Methods We conducted a prospective data collection study with retrospective analysis of registered data. Patients were followed up for 5 years (1-year observation DW changes subsequent 4-year follow-up). The outcome was all-cause mortality. predictors 1-year rates. hazard ratios (HRs) mortality calculated using multivariable Cox regression analysis,...
Introduction: The dose-response relationship between serum magnesium (sMg) and atrial fibrillation (AF) the contribution of dysmagnesemia to AF among hemodialysis patients remain unknown. Hence, we examined correlation sMg estimated extent in this population. Methods: This was a nationwide cross-sectional study on Japanese Society for Dialysis Therapy registry, also known as Renal Data Registry (JRDR), encompassing population dialysis centers, end 2019. Eligible participants were adult...