A5049789886- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Cancer-related molecular mechanisms research
- Ultrasound Imaging and Elastography
- Liver Disease and Transplantation
- Ultrasound and Hyperthermia Applications
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Animal Virus Infections Studies
- RNA modifications and cancer
- Hepatocellular Carcinoma Treatment and Prognosis
- Photoacoustic and Ultrasonic Imaging
- Ferroptosis and cancer prognosis
- Liver Diseases and Immunity
- Organ Transplantation Techniques and Outcomes
- Hepatitis C virus research
- Health Systems, Economic Evaluations, Quality of Life
- Pancreatitis Pathology and Treatment
- Aquaculture disease management and microbiota
- Organic Electronics and Photovoltaics
- Cancer-related Molecular Pathways
- Cancer Immunotherapy and Biomarkers
- Ultrasonics and Acoustic Wave Propagation
- Lung Cancer Treatments and Mutations
- Endometriosis Research and Treatment
Hong Kong Baptist University
2023-2024
Third Affiliated Hospital of Sun Yat-sen University
2015-2024
Sun Yat-sen University
2015-2024
Zhongshan Hospital
2024
Tongren Hospital
2024
Harbin Medical University
2024
Tianjin Third Central Hospital
2024
Chinese PLA General Hospital
2024
Tianjin Medical University
2024
Huashan Hospital
2024
To evaluate the individual and combined performances of two-dimensional (2D) shear-wave elastography (SWE) conventional ultrasonography (US) in assessing liver fibrosis cirrhosis to determine when 2D SWE should be added routine US.This prospective study was approved by institutional ethics committee, patients provided written informed consent. Between April 2012 March 2013, US examinations were performed 198 (mean age, 37.7 years; age range, 18-67 years) with chronic disease. Liver biopsy...
Cashmere goat skin contains two types of hair follicles (HF): primary (PHF) and secondary (SHF). Although multiple genetic determinants associated with HF formation have been identified, the molecules that determine independent morphogenesis in cashmere goats remain elusive. The growth development SHF directly influence quantity quality production. Here, we report transcriptome profiling analysis nine samples from using 60- 120-day-old embryos (E60 E120, respectively), as well newborns (NB),...
Oxidized low‑density lipoprotein (oxLDL)‑induced endothelial cell apoptosis is considered to be important in atherogenesis. MicroRNA (miR)‑590 has been reported inhibit oxLDL‑induced apoptosis. However, the mechanism underlying inhibition of by miR‑590 remains elucidated. In present study, expression levels were quantified using reverse transcription‑quantitative polymerase chain reaction analysis. Cell was investigated Hoechst staining and flow cytometry, viability measured an MTS method....
Adipose tissues are phenotypically, metabolically and functionally heterogeneous based on the sites of their deposition. Undesirable fat deposits in body often detrimental to animal human health. To unravel potential underlying mechanisms governing accumulation adipose various regions body, i.e., subcutaneous (SAT), visceral (VAT) tail (TAT), we profiled transcriptomes from Tan sheep, a Chinese indigenous breed with notable using RNA-seq. Upon comparison, identified total 1,058...
Abstract Atherosclerosis is a chronic multifactorial inflammatory disease with high prevalence worldwide, and has become the leading cause of death. The present study was designed to investigate impact high-fat diet on ApoE(−/−) mice exhibiting atherosclerosis by detecting genome-wide expression profile lncRNAs mRNAs. A total 354 differentially expressed were identified (≥2.0 folds). Simultaneously, 357 mRNAs from same chip found. differences consistent in both qPCR microarray detection....
Background Little is known about the benefits of use dispersion slope (DS) as a viscosity-related parameter derived from two-dimensional (2D) shear-wave elastography (SWE) in stratification hepatic pathologic stages. Purpose To evaluate whether DS an additional can improve diagnostic performance detecting liver necroinflammation, fibrosis, and steatosis. Materials Methods In this prospective study, consecutive participants with chronic disease who underwent biopsy 2D SWE were recruited...
Diabetes was an increasing public health problem nowadays. Accumulating evidences had shed a light on the involvement of endothelial cell dysfunction in pathogenesis diabetes-associated vascular diseases. MiR-21, multiple-functional miRNA, evidenced to be involved dysfunction, however, underlying molecular mechanisms were still unknown. In current study, we investigated intrinsic link between miR-21 and high glucose-induced dysfunction. We demonstrated that expression elevated circulating...
Background Liver stiffness measurement has been proposed as a noninvasive marker for predicting liver-related complications of cirrhosis. Purpose To evaluate the predictive value liver by using two-dimensional (2D) shear-wave elastography (SWE) events among patients with chronic hepatitis B. Materials and Methods This retrospective study recruited consecutive B who were referred biopsy between May 2011 2015. All underwent 2D SWE before biopsy, subset transient elastography. Patients followed...
Background Noninvasive evaluation of metabolic dysfunction-associated fatty liver disease (MAFLD) with multiparametric US is essential, but multicenter studies are lacking. Purpose To evaluate the ability attenuation imaging (ATI) and two-dimensional (2D) shear-wave elastography (SWE) for predicting steatohepatitis (MASH) in participants MAFLD, regardless hepatitis B virus infection status. Materials Methods This prospective cross-sectional study consecutive adults MAFLD who underwent ATI 2D...
The aim of the study was to determine whether polymorphisms in toll-like receptor 4 (TLR4) confer susceptibility rheumatoid arthritis (RA) and juvenile idiopathic (JIA) a central south Chinese Han population. Genotyping for six well studied (rs4986790, rs4986791, rs10759932, rs41426344, rs11536889 rs7873784) TLR4 gene were conducted 1074 unrelated patients with RA 1692 healthy control subjects, as 217 JIA 378 subjects using direct sequencing technique. Comparisons between cases controls...