Journal Article Expression of messenger ribonucleic acid encoding cytochrome P450 side-chain cleavage, p450 17 alpha-hydroxylase, and aromatase in bovine follicles during the first follicular wave Get access Z Xu, Xu 1Department Animal Sciences, University Missouri, Columbia 65211. Search for other works by this author on: Oxford Academic Google Scholar H A Garverick, Garverick G W Smith, Smith M F S Hamilton, Hamilton R Youngquist Endocrinology, Volume 136, Issue 3, 1 March 1995, Pages...

Background Cervical cancer (CC) is a global public health problem. We aimed to evaluate the and regional CC burden between 1990 2021, identify attributable risk factors, project its up 2035. Methods Data were extracted from Global Burden of Disease Study incidence, mortality, age-standardized incidence rate (ASIR), death (ASDR), disability-adjusted life years (DALYs), factors 2021 analyzed. The impacts geographical variations, different age groups, socio-demographic index (SDI) on morbidity...

Using micro/nanorobots (MNRs) for targeted therapy within the human body is an emerging research direction in biomedical science. These nanoscale to microscale miniature robots possess specificity and precision that are lacking most traditional treatment modalities. Currently, on electrically controlled still its early stages, with researchers primarily focusing fabrication manipulation of these meet complex clinical demands. This review aims compare fabrication, powering, locomotion various...

Background . To evaluate serum chemerin levels in patients with osteoporosis and healthy controls to investigate the relationship between bone mineral density (BMD). Methods An age- gender-matched case-control study was conducted. Pearson’s correlation test performed BMD. Results There were 93 included group matched controls. Serum level significantly higher (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mrow><mml:mn>87.27±5.80</mml:mn></mml:mrow></mml:math> ng/mL)...

Osteoporosis is a result of the imbalance between osteoblasts and osteoclasts quantities, which closely correlated with osteogenic differentiation (OD). Leucocyte cell-derived chemotaxin 2 (LECT2) has been reported as regulatory factor in some chronic diseases such hepatitis through mediating downstream target gene β-catenin. Additionally, Wnt/β-catenin also crucial modulatory signal pathway OD. Mesenchymal stem cells (MSC) kind mesodermal cells; its direction discovered affected by...

Objective: This study aims to analyze the relationship among clinical features, radiologic characteristics and pathological diagnosis in patients with solitary pulmonary nodules, establish a prediction model for probability of malignancy. Methods: Clinical data 372 nodules who underwent surgical resection definite postoperative were retrospectively analyzed. In these cases, we collected features including gender, age, smoking history, history tumor, family cancer, location lesion,...

We developed a few-shot learning (FSL) framework for the diagnosis of osteopenia and osteoporosis in knee X-ray images.

To investigate the short-term efficacy and safety of Endostar combined with concurrent chemoradiotherapy in treatment locally advanced cervical squamous cell carcinoma (LACSC).A total 91 patients LACSC admitted to First Affiliated Hospital Anhui Medical University from June 2019 December 2020 were randomly assigned either experimental group (n = 48) or control 43). The received radiotherapy for cancer paclitaxel platinum chemotherapy (CCRT), continuous intravenous infusion anti-angiogenic...

As a novel adipokine, CTRP3 involves in various functions of energy metabolism. Recent advance reveals complex interaction between bone and adipose tissue via the secretion adipokines.A hospital-based case-control study was conducted to investigate role serum osteoporosis among postmenopausal women.Serum levels osteocalcin were measured. Bone mineral density (BMD) obtained on femoral neck lumbar spines by dual X-ray absorptiometry.Serum level lower subjects with (76.7±22.1 ng/ml) than it...

Osteosarcoma is one of the most common primary malignant bone tumors. The inhibitor growth family protein 5 has been identified as a tumor suppressor in many cancers. In this study, we confirmed downregulation both and messenger RNA levels cancer tissues using Western blot real-time polymerase chain reaction. order to find antitumor roles 5, osteosarcoma cells, HOS, MG63 were transfected with plasmid pCDNA-3.1-inhibitor 5. Overexpression Inhibitor could induce apoptosis inhibit cell...

The low bone mineral density due to abnormally activated osteoclasts can induce disorders such as osteopenia and osteoporosis. MiR-25-3p modulates sphingosine-1-phosphate receptor 1 (S1PR1) expression enhance osteoclast motivation. association between miR-25 rs41274221 polymorphism osteoporosis susceptibility is unknown. Herein, 300 patients with 320 healthy controls were genotyped using polymerase chain reaction Sanger sequencing explore the role of in odds ratios (ORs) 95% confidence...

Hyperuricemia can lead to synovial hyperplasia in the wrist. In severe cases, it deposition of gouty stone carpal tunnel, resulting increased pressure tunnel and compression median nerve cause syndrome (CTS), which is called (GCTS). As for surgical treatment syndrome, scholars have different opinions on whether necessary remove superficial flexor tendon. The purpose this study was compare clinical efficacy trimming resection diseased tendon syndrome.Clinical data were collected from May 2016...

Many kinds of malignant disorders present as exfoliative dermatitis (erythroderma), however, coincident clearcell renal cell carcinoma (ccRCC) and erythroderma has not been reported. A case synchronous ccRCC in a 57-year-old man is presented here. After the diagnosis kidney bulk through CT, patient had transperitoneal laparoscopic radical nephrectomy, syndrome disappeared after surgery. The experience current suggests that may resolve spontaneously nephrotomy.

As a novel hepatokine, fetuin B involves in various functions of energy metabolism. Recent advance reveals complex interaction between bone and liver via the secretion hepatokines. The association serum osteoporosis was evaluated 4-year hospital-based prospective study 1,370 Chinese postmenopausal women.Bone mineral densities (BMDs) were obtained on femoral neck lumbar spines by dual X-ray absorptiometry. Serum level tested enzyme-linked immunosorbent assay.Of participants baseline (2012),...

Acidosis is the most common complication that seriously affects prognosis of acute respiratory distress syndrome (ARDS). Acid-sensitive ion channel 1a (ASIC1a) activated in acidic environments to regulate inflammatory process. However, role ASIC1a ARDS unclear. In this study, we examined expression airway epithelial cells an environment. We then investigated whether blocking could inhibit pyroptosis and molecular mechanism. mouse lung injury (ALI) model, observed changes histopathology,...

Objective To investigate the effect of bone cement distribution on efficacy vertebroplasty. Methods From January 2013 to June 2016, a total 132 cases (132 vertebrae) with single segment osteoporotic thoracolumbar vertebral fractures underwent parallel vertebroplasty surgery, and there were 57 male, 75 female, an average age (71.6±2.2) years old (ranged from 65 86 old). On basis postoperative X-ray films divided into 3 groups. The was biased lateral side body (partial group, 35 cases),...

Paired basic amino acid-cleaving enzyme 4 (PACE4), a proprotein convertase, is involved in the activation of aggrecanases (ADAMTS-4 and ADAMTS-5) osteoarthritic cytokine-stimulated cartilage. Activated cause aggrecan degradation thus, contribute to osteoarthritis (OA). In this study, we investigated association between PACE4 gene polymorphisms OA risk. One single-nucleotide polymorphism (rs4965833) was genotyped 432 patients 523 healthy controls using matrix-assisted laser...