A5100408288- Tuberculosis Research and Epidemiology
- Infectious Diseases and Tuberculosis
- Pneumocystis jirovecii pneumonia detection and treatment
- Mycobacterium research and diagnosis
- Diagnosis and treatment of tuberculosis
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Pneumonia and Respiratory Infections
- Genomic variations and chromosomal abnormalities
- Corneal Surgery and Treatments
- Prenatal Screening and Diagnostics
- Parvovirus B19 Infection Studies
- Liver Disease Diagnosis and Treatment
- Antimicrobial Resistance in Staphylococcus
- SARS-CoV-2 and COVID-19 Research
- Bacterial Identification and Susceptibility Testing
- Pancreatitis Pathology and Treatment
- Lymphoma Diagnosis and Treatment
- Glaucoma and retinal disorders
- Medical Research and Treatments
- Parasitic Diseases Research and Treatment
- Parasites and Host Interactions
- Bacterial biofilms and quorum sensing
- Ocular Infections and Treatments
- Psoriasis: Treatment and Pathogenesis
Public Health Clinical Center of Chengdu
2016-2024
Guangdong Province Women and Children Hospital
2017-2023
Tongde Hospital of Zhejiang Province
2022
Nanjing Municipal Center for Disease Control And Prevention
2021
Sichuan University
2020
West China Hospital of Sichuan University
2020
Qilu Hospital of Shandong University
2020
Yantaishan Hospital
2019
Zhongshan People's Hospital
2017
Chinese Center For Disease Control and Prevention
2017
Abstract Background The duration of humoral and T B cell response after the infection severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains unclear. Methods We performed a cross-sectional study to assess virus-specific antibody memory responses in disease 2019 (COVID-19) patients up 343 days infection. Neutralizing antibodies against receptor-binding domain, spike, nucleoprotein SARS-CoV-2 were measured. Virus-specific analyzed. Results enrolled 59 with COVID-19, including 38...
Abstract An examination of the Companion Animal Parasite Council’s (CAPC) canine heartworm data to clarify spatial prevalence in United States. Factors thought influence risk disease, as identified a recent CAPC workshop, are discussed.
China has the world's second largest burden of multidrug-resistant tuberculosis (MDR-TB; resistance to at least isoniazid and rifampicin), with an estimated 57,000 cases (range, 48,000-67,000) among notified pulmonary TB patients in 2015. During October 1, 2006-June 30, 2014, expanded MDR-TB care through a partnership Global Fund Fight AIDS, Tuberculosis, Malaria (Global Fund). We analyzed data on site expansion, patient enrolment, treatment outcomes, cost per patient, overall programme...
Background The prevalence of drug-resistant tuberculosis (DR-TB) has brought severe challenges to the prevention and control tuberculosis. Studies have explored status antituberculosis drug (ATD) resistance in different regions China. However, few studies focused on DR-TB Sichuan date. Due large population Sichuan, detailed investigations burden are needed. objective this study was investigate characteristics TB isolates from patients with without HIV (TB-HIV TBw/oHIV patients) Chengdu,...
Background: Some patients with comorbidities and rapid disease progression have a poor prognosis. Aim: We aimed to investigate the characteristics of their relationship outcomes COVID-19 patients. Methods: A total 718 were divided into five clinical type groups eight age-interval groups. The compared between different groups, relationships assessed. Results: Approximately 91.23% (655/718) younger than 60 years old. 64.76% (465/718) had one or more comorbidities, common included non-alcoholic...
Objectives: To determine the effects of nutritional nursing intervention based on glycemic load (GL) for patients with gestational diabetes mellitus. Material and methods: One hundred thirty-four diagnosed mellitus at our hospital were selected from March 2015 to 2017 randomly divided into observation (n = 67) control groups 67). All in received conventional nursing. In addition, group GL. The changes blood glucose levels pregnancy outcomes compared between two after intervention. Results:...
Abstract We investigated the drug resistance of Mycobacterium tuberculosis isolates from patients with (TB) and HIV, those diagnosed only TB in Sichuan, China. were obtained January 2018 to December 2020 subjected susceptibility testing (DST) 11 anti-TB drugs GeneXpert MTB/RIF testing. The overall proportion drug-resistant (DR-TB) was 32.1% ( n = 10 946). HIV not universally available for outpatient cases, 29.5% (3227/10 946) cases had results. observed multidrug-resistant (MDR-TB) almost...
Background Osteoarticular tuberculosis (TB) is an uncommon form of extrapulmonary TB. In this study, we analyzed the epidemiological characteristics, common sites, and drug resistance profiles osteoarticular TB infections occurring in southwest China. Methods A total 3,254 cases patients clinically diagnosed with between 2013 2021 were retrospectively analyzed. Patients' demographic clinical characteristics collected. Drug sensitivity testing was performed using microporous plate ratio...
To evaluate postoperative pain, uncorrected visual acuity (UCVA), and cornea haze value after transepithelial photorefractive keratectomy (T-PRK) performed with aspherical ablation profile using SCHWIND ESIRIS excimer laser.Retrospective case series. Fifty-nice eyes (32 patients) myopia associated or without astigmatism underwent phototherapeutic (PTK) followed by (PRK) which Optimized Refractive Keratecomy (ORK)-CAM software based on laser. Postoperative pain scale was measured a...
Abstract Background Sichuan is a province located in southwestern China, which have higher incidence of tuberculosis (TB). This study aimed to analyze the epidemiological and clinical characteristics, as well drug resistance culture-confirmed children with Tuberculosis meningitis (TBM) Southwest China. Methods We performed retrospective on (< 14 years old) cerebrospinal fluid (CSF) TBM between January 2013 December 2018 at Public Health Clinical Center Chengdu (PHCCC). Mycobacterium (MTB)...
Background: Human-immunodeficiency virus (HIV) infection is increasing worldwide and nontuberculous mycobacteria (NTM) an established microbiologic cause of pulmonary disease, lymphadenitis, disseminated disease in cases advanced immune suppression. Data on patients coinfected with HIV NTM are limited. Thus, this study aimed to analyze the clinical characteristics, drug resistance, pathogen spectrum both Chengdu area China. Methods: 59 collected from Public Health Clinical Center Chengdu,...
Staphylococcus aureus remains a dangerous pathogen and poses great threat to public health worldwide. The prevalence of the S. clonotype is temporally geographically variable. genomic phenotypic characteristics isolates in Tianjin, which among four big municipalities China, are unclear. In present study, 201 nonduplicate isolates, including 70 methicillin-resistant (MRSA) 131 methicillin-susceptible (MSSA), were collected from 2015 2021 tertiary hospital Tianjin. Whole-genome sequencing was...
Generalized pustular psoriasis (GPP) is a rare and severe form of presenting with erythematous, aseptic pustules. Common systemic symptoms include fever myalgias. The presentation GPP resembles acute generalized exanthematous pustulosis (AGEP). However, the treatment these two pathologies differs. While AGEP self-limiting treated topical corticosteroids constrain steroids. avoids corticosteroid, choosing acitretin, methotrexate, cyclosporine as first-line agents. In this case report,...
The non-invasive prenatal testing that evaluates circulating cell free DNA, and has been established as an additional pregnancy test for detecting the common fetal trisomies 21, 18 13 is rapidly revolutionizing screening a result of its increased sensitivity specificity. However, false positive negative results still exist. We presented case in which were normal at 15 gestational age (GA), but ultrasound examination 30GA showed fetus had heart abnormalities, third trimester 33GA noted...
The purpose of this study was to evaluate the performance noninvasive prenatal testing (NIPT) for detection chromosomal aneuploidies and copy number variations (CNVs) in twin pregnancies.A cohort 2010 women with pregnancies recruited. 1331 patients opted NIPT, 679 expanded NIPT (NIPT-plus). All high-risk were advised undergo invasive diagnosis. participants followed up until 6 months after birth.Twenty-two cases predicted have a high risk chromosome abnormalities by which 14 pregnant...
There are few reports on extrapulmonary tuberculosis/human immunodeficiency virus (EPTB/HIV) co-infection patients, especially the resistance profile of culture-confirmed EPTB. The purpose our study was to analyse clinical characteristics, common sites and drug EPTB/HIV patients in Southwest China (2017-2020).A total 201 cases were selected for this study. Patient demographics characteristics collected. Mycobacterium tuberculosis susceptibility testing (DST) performed by microporous plate...
Abstract The aim of this study was to investigate the epidemiological characteristics and profile drug-resistant tuberculosis (DR-TB) among children with TB in Sichuan province China. From January 2015 December 2018, microbiological culture-confirmed child cases (aged <15 years old) were enrolled retrospectively. Epidemiological clinical information from these cases, drug susceptibility testing results isolates collected analyzed. Of 317 16.7% (53/317) aged under 5 old. 54.9% Tibetans,...
Background The data report of a large sample, dynamic epidemiology, and characteristic analysis pediatric tuberculosis (TB) in Southwest China is not clear. Herein, we conducted descriptive geographical distribution study TB inpatients for more than 20 years. Methods Patients with were recruited from October 2002 to September 2022 based on etiology or clinical confirmation. Extract hospitalization medical record information each patient. chart cases used display the trend case flow segmented...
Objective To analyze the status of infection and drug resistance nontuberculous mycobacteria (NTM) its clinical relevance in Sichuan area. Methods Mycobacteria laboratory specimens from January 2014 to December 2015 Public Health Clinical Center Chengdu were retrospectively collected analyzed. NTM identification was performed by gene chip or 16S rDNA sequencing. Drug susceptibility test using proportion method. 87 isolates patients The chi-square used for rates comparison between...
To investigate the accuracy and consistency of detection BCR-ABL tyrosine kinase domain point mutation among different laboratories.Every one 6 laboratories prepared 10 cDNA samples from inhibitors resistant (P210 or P190) positive patients'bone marrow peripheral blood. Each sample was divided into aliquots delivered to laboratories. All tested mutations 60 according their own protocols. Peking University People's Hospital analyzed comparison results based on both reports sequencing...
Abstract Background : Sichuan is a province located in southwestern China, which have higher incidence of tuberculosis (TB).This study aimed to analyze the epidemiological and clinical characteristics, as well drug resistance culture-confirmed children with Tuberculosis meningitis (TBM) Southwest China. Materials Methods: We performed retrospective on (<14 years old) cerebrospinal fluid (CSF) TBM between January 2013 December 2018 at Public Health Clinical Center Chengdu (PHCCC)....