- Reproductive Biology and Fertility
- Sperm and Testicular Function
- Seed Germination and Physiology
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Energetic Materials and Combustion
- Reproductive Health and Technologies
- Diabetes Management and Research
- Ionic liquids properties and applications
- Tissue Engineering and Regenerative Medicine
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Metamaterials and Metasurfaces Applications
- Ovarian function and disorders
- Electrospun Nanofibers in Biomedical Applications
- Gut microbiota and health
- Diabetes Treatment and Management
- Blood properties and coagulation
- Thermal and Kinetic Analysis
- Mycotoxins in Agriculture and Food
- Freezing and Crystallization Processes
- Innovative Microfluidic and Catalytic Techniques Innovation
- 3D Printing in Biomedical Research
- Tryptophan and brain disorders
- Plasmonic and Surface Plasmon Research
- Erythrocyte Function and Pathophysiology
University of Shanghai for Science and Technology
2014-2025
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
2024-2025
Shandong Provincial Hospital
2022-2025
Shandong First Medical University
2022-2025
Shandong University
2022-2025
Wuhan University
2023-2024
Zhongda Hospital Southeast University
2024
Nanjing Medical University
2021-2024
Shanghai Innovative Research Center of Traditional Chinese Medicine
2024
Capital Normal University
2024
Abstract Currently, wound infection is an important health problem for the public. Wound can not only hinder healing but it also lead to serious complications. Injectable dressings with biocompatible and antibacterial properties promote during skin infections reduce antibiotic use. Here, we used glycidyl methacrylate (GMA) modify ε-polylysine (ε-PL) γ-poly(glutamic acid) (γ-PGA) produce ε-polylysine-glycidyl (ε-PL-GMA) acid)-glycidyl (γ-PGA-GMA). Subsequently, ε-PL-GMA- γ-PGA-GMA-based...
Some novel Brønsted acidic ionic liquids (TSILs) that bear an alkane sulfonic acid group in acyclic trialkanylammonium cation were synthesized and their uses as dual solvent−catalysts for Fischer esterification reactions of acetic acid, metacetonic benzoic with ethanol, butanol, benzyl alcohol investigated. The completed smoothly at room temperature to 110 °C 1.5−3.0 h good yields 88−95%. results indicate catalytic activity depends on anion acidity the solubility starting material TSILs....
Autism spectrum disorder (ASD) has been associated with intrauterine growth restriction (IUGR), but the underlying mechanisms are unclear.We found that IUGR rat model induced by prenatal caffeine exposure (PCE) showed ASD-like symptoms, accompanied altered gut microbiota and reduced production of indole 3-propionic acid (IPA), a microbiota-specific metabolite ligand aryl hydrocarbon receptor (AHR). children also had serum IPA level consistent animal model. We demonstrated dysregulated...
The cocontamination of food by several mycotoxins and heavy metals poses significant health risks, their combined toxic effects remain poorly understood. Particularly, specific studies exploring impact on ferroptosis limited. In this work, we investigated the a mycotoxin, called deoxynivalenol (DON), metal, plumbum (Pb), explored potential mechanisms DON Pb co-occurrence via excessive ROS-induced in HK-2 cells. It was found that toxicity Pb2+ showed synergism at low concentrations an...
Smart cities are confronted with a variety of disaster threats. Among them, natural fires pose serious threat to human lives, the environment, and asset security. In view fact that existing research mostly focuses on analysis accident precursors, this paper proposes dynamic risk-modeling method based Stochastic Petri Nets (SPN) Bayesian theory deeply explore evolution mechanism urban fires. The SPN model is constructed through language processing techniques, which discretize process. Then,...
Co-contamination of multiple mycotoxins in feed has become one the most important issues world. In this study, characteristics and interactions co-contamination among 15 were explored dairy cow feed, including total mixed ration (TMR), silage, maize, hay feed. The results showed that four feeds constantly contaminated with mycotoxins, zearalenone (ZEN), fumonisins (FBs), deoxynivalenol (DON), ochratoxin A (OTA), T-2 toxin (T-2), aflatoxins (AFs). contamination level each mycotoxin was low,...
Dynamic and changeable business scenarios pose significant challenges to the adaptability verifiability of process models. Despite its widespread adoption as an ISO-standard modeling language, Business Process Model Notation (BPMN) faces inherent limitations in formal semantics verification capabilities, hindering mathematical validation evolution behaviors under scenario changes. To address these challenges, this paper proposes a collaborative framework integrating BPMN with hierarchical...
Abstract An acid‐free N‐nitrosation/nitration of the N−H bonds in secondary amines with Fe(NO 3 ) ⋅ 9H 2 O as nitroso/nitro source through an electrocatalyzed radical coupling reaction was developed. Cyclic aliphatic and N‐heteroaromatic compounds were N‐nitrosated N‐nitrated, respectively, under mild conditions. Control competition experiments, well kinetic studies, demonstrate that N‐nitrosation N‐nitration involve two different pathways involving N + . radicals. Moreover, electrocatalysis...
Abstract Gelatin methacrylate (GelMA) hydrogels are expected to be ideal skin tissue engineering dressings for a wide range of clinical treatments. Herein, we report the preparation GelMA or antifreeze hydrogel sheets with different concentrations, crosslinking times, and cryoprotectant (CPA) concentrations. The crystallization properties were studied by cryomicroscopy differential scanning calorimetry (DSC). It was found that growth ice crystals slower when concentration more than 7%. 10%...
A series of N-methylene-bridged polynitropyrazoles and 5-amino-1,2,4-oxadiazole derivatives were successfully synthesized. All these compounds determined by single-crystal X-ray diffraction. N...
Orderly and stage-specifically expressed proteins are essential for spermatogenesis, proteases play a key role in protein activation function. The present study aimed to investigate serine protease 55 (PRSS55), which was reported sperm-uterotubal junction (UTJ) migration sperm-zona pellucida (ZP) binding. We found that PRSS55 specifically testicular spermatids epididymal spermatozoa. By constructing knockout mice targeting all transcripts of Prss55, we demonstrated deletion Prss55 resulted...
Serine proteases are involved in many physiological activities as initiators of proteolytic cascades, and some members have been reported to play roles male reproduction. Transmembrane serine protease 12 (TMPRSS12) has shown regulate sperm motility uterotubal junction migration mice, but its role the testis remains unknown. In this study, we verified that TMPRSS12 was expressed spermatocytes spermatids acrosome sperm. Mice deficient Tmprss12 exhibited sterility. meiosis, demonstrated...
Abstract Gelatin methacrylate (GelMA) hydrogels have been widely used in tissue engineering because of their excellent biological and physical properties. Here, we a microfluidic flow-focusing chip based on polymethyl to fabricate cell-laden GelMA hydrogel microspheres. Structures the throat region photo crosslinking chip, flow rate ratio oil phase, concentration were optimized obtain stable suitable size Cell-laden microspheres can be cryopreserved by slow freezing rapid freezing. The...