A5054615745- COVID-19 and healthcare impacts
- COVID-19 Clinical Research Studies
- COVID-19 epidemiological studies
- Healthcare cost, quality, practices
- Vibrio bacteria research studies
- Climate Change and Health Impacts
- Long-Term Effects of COVID-19
- Venous Thromboembolism Diagnosis and Management
- Influenza Virus Research Studies
- Atrial Fibrillation Management and Outcomes
- COVID-19 and Mental Health
- Acute Myocardial Infarction Research
- Pharmacological Receptor Mechanisms and Effects
- Liver Disease Diagnosis and Treatment
- Lipoproteins and Cardiovascular Health
- Chronic Disease Management Strategies
- Viral Infections and Vectors
- Infection Control and Ventilation
- Geochemistry and Geologic Mapping
- Leptospirosis research and findings
- Acute Ischemic Stroke Management
- Cardiovascular Function and Risk Factors
- Cardiovascular Health and Risk Factors
- Viral Infections and Immunology Research
- Speech and Audio Processing
United States Space Force
2022-2024
U.S. Air Force Space Command
2022-2024
Danish National Research Foundation
2020-2022
Nordsjællands Hospital
2020
Hjerteforeningen
2020
University of Copenhagen
2017-2019
Birmingham City Hospital
1986
Lahey Hospital and Medical Center
1957-1963
United States Public Health Service
1957
It has been hypothesized that angiotensin-converting enzyme inhibitors (ACEIs)/angiotensin receptor blockers (ARBs) may make patients more susceptible to coronavirus disease 2019 (COVID-19) and worse outcomes through upregulation of the functional virus, 2.To examine whether use ACEI/ARBs was associated with COVID-19 diagnosis in COVID-19.To among COVID-19, a retrospective cohort study using data from Danish national administrative registries conducted. Patients February 22 May 4, 2020, were...
◼ stroke R ecent studies have linked coronavirus disease 2019 (COVID-19) infection with an increased risk of ischemic and acute myocardial infarction (AMI). 1,2However, the evidence base is small current data are limited mainly to case reports 2 cohort studies. 1-4Therefore, in a nationwide registerbased study considering all patients diagnosed COVID-19 at Danish hospitals, we assessed association between AMI during phase using self-controlled series method. 5 We used registers identify...
Male sex has been associated with severe coronavirus disease 2019 (COVID-19) infection. We examined the association between male and COVID-19 infection if an increased risk remains after adjustment for age comorbidities.Nationwide register-based follow-up study of patients in Denmark until 16 May 2020. Average ratio comparing 30-day composite outcome all-cause death, diagnosis or intensive care unit (ICU) admission men versus women standardized to comorbidity distribution all were derived...
Abstract Aim To determine the incidence, patient characteristics, and related events associated with new-onset atrial fibrillation (AF) during a national COVID-19 lockdown. Methods results Using nationwide Danish registries, we included all patients, aged 18–90 years, receiving AF diagnosis first 3 months of 2019 2020. The main comparison was between patients diagnosed lockdown (12 March 12–1 April 2020) in corresponding period 1 year previously. We found lower incidence weeks compared...
Background: The Danish government ordered a public lockdown on March 12, 2020, because of the coronavirus disease 2019 (COVID-19) pandemic. We investigated immediate consequences such for patients with heart failure (HF). Methods: Using nationwide administrative databases, we incidence new-onset HF and hospitalizations worsening before after (January 1 to 11 versus 12 31) in 2020 2019. also mortality all COVID-19–infected HF. Results: Rates between January were comparable (1.83 1.78 per 10...
Abstract Background On 13 March 2020, the Danish authorities imposed extensive nationwide lockdown measures to prevent spread of coronavirus disease 2019 (COVID-19) and reallocated limited healthcare resources. We investigated mortality rates, overall according location, in patients with established cardiovascular before, during, after these measures. Methods results Using registries, we identified a dynamic cohort comprising all citizens (i.e. history ischaemic heart disease, stroke,...
This study aimed to explore return work after COVID-19 and how disease severity affects this.This is a Nationwide Danish registry-based cohort using retrospective follow-up design.Patients with first-time positive SARS-CoV-2 polymerase chain reaction test between 1 January 2020 30 May 2020, including 18-64 years old, 30-day survivors, available the workforce at time of first were included. Admission types (i.e. no admission, admission non-intensive care unit [ICU] department ICU) was...
To investigate the association between recent statin exposure and risk of severe COVID-19 infection all-cause mortality in patients with Denmark.Observational cohort study using data from Danish nationwide registries.Patients diagnosed 22 February 2020 to 17 May were followed date diagnosis until outcome interest, death or 2020.Use statins, defined as a redeemed drug prescription 6 months prior diagnosis.All-cause mortality, composite.The population comprised 4842 (median age 54 years...
Pre-existing cardiovascular diseases (CVDs) have been proposed to identify patients at higher risk of adverse coronavirus disease 2019 (COVID-19) outcomes, but existing evidence is conflicting. Thus, it unclear whether pre-existing CVDs are independently important predictors for severe COVID-19. In a nationwide Danish cohort hospital-screened COVID-19 aged ≥40, we investigated if predict the 30-day (i) composite outcome and (ii) all-cause mortality. We estimated risks using Cox regression...
Abstract Aims In a continuously ageing population of patients with congenital heart disease (CHD), understanding the long-term risk morbidity is crucial. The aim this study was to compare lifetime risks developing comorbidities in simple CHD and matched controls. Methods results Using Danish nationwide registers spanning from 1977 2018, cases were defined as isolated atrial septal defect (ASD), ventricular (VSD), pulmonary stenosis, or patent ductus arteriosus surviving until at least 5...
Although cholera is considered the quintessential long-cycle waterborne disease, studies have emphasized existence of short-cycle (food, household) transmission. We investigated singular Danish epidemics (in 1853) to elucidate epidemiological parameters and modes spread.Using time series data from cities with different water systems, we estimated intrinsic transmissibility (R0). Accessing cause-specific mortality data, studied clinical severity age-specific impact. From physicians'...
Recommendations regarding ibuprofen use in relation to coronavirus disease 2019 (COVID‐19) have been conflicting. We examined the risk of severe COVID‐19 between ibuprofen‐prescribed and non‐ibuprofen patients with a nationwide register‐based study Denmark end February 2020 May 16, 2020. Patients heart failure ( n = 208), < 30 years 575), prescribed other nonsteroidal anti‐inflammatory drugs 57) were excluded. prescription claims January 1, 2020, before diagnosis or April 30, (last...
Background and aimsFew studies have determined whether the declining incidence of myocardial infarction carries into current decade, how it is affected by age sex. We aimed to determine age- sex-specific changes in Denmark from 2005 through 2021.MethodsFirst-time admissions adults aged ≥18 years were identified Danish nationwide registries. Incidence rates per 100,000 persons with 95% confidence intervals (CI) calculated across calendar year, sex, groups (≤49, 50–69, 70–84, ≥85 years). also...
Abstract Objective To investigate the transmission of faecal bacteria by flies to food under natural settings. Methods Over a period 2 months, paired (exposed and non‐exposed) containers with cooked rice were placed on ground in kitchen areas an urban slum area Dhaka, Bangladesh, numbers landing exposed counted. Following exposure, surface was microbiologically molecularly analysed for presence Escherichia coli genes diarrhoeagenic E. Shigella strains. Results Rice at greater risk ( P <...
Background Planning interventions to respond cholera epidemics requires an understanding of the major transmission routes. Interrupting short-cycle (household, foodborne) may require different approaches as compared long-cycle (environmentally-mediated/waterborne) transmission. However, differentiating relative contribution short- and routes has remained difficult, most outbreak control efforts focus on interrupting Here we use high-resolution epidemiological municipal infrastructure data...
On March 13, 2020, the Danish authorities imposed extensive nationwide lockdown measures to prevent spread of novel coronavirus disease 2019 (COVID-19) and reprioritized limited healthcare resources.However, this strategy may have a detrimental effect on medical care patients with other acute conditions such as stroke increase reluctance symptoms contact emergency services.To shed light possible collateral effects reprioritization within system, we performed cohort study investigate...
Denmark implemented early widespread social distancing to reduce pressure on the healthcare system from coronavirus disease 2019 (COVID-19) pandemic, with aims mortality. Unintended consequences might be delays in treatment for other diseases and subsequent We examined national all-cause mortality comparing weeks 1-27 2020 2015-2019. This registry-based study used Danish registry data until 5 July 2020. rates among all deaths recorded 2015 chronic conditions (cardiovascular (cardiac &...
PRINZMETAL and Kennamer1 first reported on the use of ACTH in 1954 to correct complete heart block secondary myocardial infarction. They believed that, incomplete septal infarction or infarctions near septum, interference with atrioventricular conduction that often culminates may be due many cases not destruction but only inflammation node specialized conductive tissue septum. If this is true, anything reduces body tissues should help re-establish normal these cases. The anti-inflammatory...
Abstract Aim To assess the risk of stroke and thromboembolism in patients with atrial fibrillation (AF) based on factor combinations CHA2DS2-VASc score. Methods results Using nationwide Danish registries, AF were included from 1997 to 2015 this retrospective observational study. A multiple logistic regression, including interactions history age at AF, calendar year score factors (congestive heart failure, hypertension, diabetes, vascular disease, female sex) used predict personalized risks...
The hospitalization of patients with MI has decreased during global lockdown due to the COVID-19 pandemic. Whether this decrease is associated more severe MI, e.g. MI-CS, unknown. We aimed examine association Corona virus disease (COVID-19) pandemic and incidence acute myocardial infarction cardiogenic shock (MI-CS).On March 11, 2020, Danish government announced national lock-down. Using nationwide registries, we identified hospitalized MI-CS. Incidence rates (IR) rate ratios (IRR) were used...
To investigate the admission rates of cardiovascular diseases, overall and according to subgroups, subsequent mortality during coronavirus disease 2019 societal lockdown (12 March 2020) reopening phase (15 April in Denmark. Using Danish nationwide registries, we identified patients with a first-time acute two periods: (i) 2 January-16 October (ii) January-15 2020. Weekly incidence admission, subtypes, periods were calculated. The rate admissions was significantly lower first weeks 2020...