A5004022583- Autoimmune Neurological Disorders and Treatments
- Infectious Diseases and Tuberculosis
- Peripheral Neuropathies and Disorders
- Polyomavirus and related diseases
- Spinal Hematomas and Complications
- Sarcoidosis and Beryllium Toxicity Research
- Multiple Sclerosis Research Studies
- Autoimmune and Inflammatory Disorders
- Myasthenia Gravis and Thymoma
- Bacterial Infections and Vaccines
- Cardiac tumors and thrombi
- Herpesvirus Infections and Treatments
- IgG4-Related and Inflammatory Diseases
- Fungal Infections and Studies
- Genetics and Neurodevelopmental Disorders
- Immunotherapy and Immune Responses
- Viral Infections and Immunology Research
- T-cell and B-cell Immunology
- Yeasts and Rust Fungi Studies
- Cerebral Venous Sinus Thrombosis
- Spinal Dysraphism and Malformations
- RNA regulation and disease
- Intracerebral and Subarachnoid Hemorrhage Research
- Pulmonary Hypertension Research and Treatments
- Neurosurgical Procedures and Complications
Tokyo Medical and Dental University
2019-2024
National Center of Neurology and Psychiatry
2024
Tsuchiura Kyodo General Hospital
2017-2021
Kyoto Prefectural University of Medicine
2021
Chiba Cancer Center
2021
Neuromyelitis optica (NMO) is an autoimmune astrocytopathy mediated by anti-AQP4 antibody-producing B cells. Recently, a B-cell subset highly expressing CD11c and T-bet, originally identified as age-associated cells, has been shown to be involved in the pathogenesis of various diseases. The objective this study was determine relationship between frequency
Rationale: OSAM is a rare ventriculoperitoneal (VP) shunt complication where cervical spinal cord compression by epidural venous plexus engorgement caused cerebrospinal fluid (CSF) overdrainage. Symmetrically indented deformity of the upper and surrounding are characteristic radiological findings. Both them typically detected on magnetic resonance imaging (MRI) enhanced computed tomography (CT). Patient concerns: The 77-year-old man who underwent placement VP without an antisiphon device to...
Although paradoxical reactions (PRs) to anti-tuberculosis (anti-TB) therapy during treatment are well-established occurrences, PRs presenting as a new lesion after the completion of extremely rare, and little is known about management such cases, particularly central nervous system (CNS) tuberculosis.A 27-year-old female, with past medical history tuberculous meningitis 10 years ago who completed anti-TB asymptomatic remnant tuberculomas in basal cistern, was admitted our hospital because...
A 42-year-old immunocompetent man developed left-sided orbital and temporal stabbing pain, accompanied by ipsilateral lacrimation conjunctival injection with periorbital edema (figure 1A). On day 10, Hutchinson sign, which is defined as zoster skin lesions in the root, dorsum, apex of nose,1 became evident severe keratoconjunctivitis iritis 1B). PCR testing blood revealed varicella-zoster virus he was diagnosed herpes ophthalmicus (HZO). sign indicates involvement nasociliary nerve, a branch...
Objective Cryptococcal meningoencephalitis (CM) causes significant morbidity and mortality in human immunodeficiency virus (HIV)-negative HIV-positive populations. White matter lesions (WMLs) have been reported both populations of CM patients; however, the mechanisms underlying WML formation remain unknown. We herein report relationship between intrathecal immune response development WMLs HIV-negative patients with CM.
Abstract Background Hypertrophic pachymeningitis (HP) is a rare disorder that involves localized or diffuse thickening of the dura mater. HP associated with various inflammatory, infectious, and malignant diseases, such as rheumatic arthritis, sarcoidosis, anti-neutrophil cytoplasmic antibody-associated vasculitis, IgG4-related disorders, syphilis, tuberculosis, bacterial fungal infections, cancer, idiopathic when evaluation fails to reveal cause. Among them, chronic infection...
<h3>Background and Objective</h3> Alexander disease (ALXDRD) is an autosomal dominant neurologic disorder caused by mutations in the glial fibrillary acidic protein (<i>GFAP</i>) gene pathologically defined Rosenthal fiber accumulation. Most are exonic missense mutations, splice site rare. We report a very-late-onset autopsied case of adult-onset ALXDRD with novel mutation. <h3>Methods</h3> Genetic testing <i>GFAP</i> was performed Sanger sequencing. Using brain tissues, transcript analysis...
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Abstract Background: Hypertrophic pachymeningitis (HP) is a rare disorder that involves localized or diffuse thickening of the dura mater. HP associated with various inflammatory, infectious, and malignant diseases, such as rheumatic arthritis, sarcoidosis, anti-neutrophil cytoplasmic antibody-associated vasculitis, IgG4-related disorders, syphilis, tuberculosis, bacterial fungal infections, cancer, idiopathic when evaluation fails to reveal cause. Among them, chronic infection...
Thursday, April 30April 14, 2020Free AccessBilaterally Synchronized Faciobrachial Dystonic Seizures in Anti-LGI1 Encephalitis: A Case Report (1724)Takahisa Mikami, Eiichiro Amano, Takahiro Iizuka, and Akira MachidaAuthors Info & AffiliationsApril 2020 issue94 (15_supplement)https://doi.org/10.1212/WNL.94.15_supplement.1724 Letters to the Editor
Aortic dissection is a rare cause of an acute ischemic stroke or transient attack (TIA). particularly challenging in patients who are eligible for thrombolysis secondary to the diagnostic difficulty within narrow time window (4.5 h) and have risk developing life-threatening hemorrhagic complications following thrombolysis. Computed tomographic angiography (CTA) has been mainstay imaging when evaluating aortic syndrome. However, it cannot be routinely performed pregnant those with renal...