A5065855964- Breastfeeding Practices and Influences
- Child Nutrition and Water Access
- Infant Nutrition and Health
- COVID-19 Impact on Reproduction
- Global Maternal and Child Health
- Birth, Development, and Health
- Infant Health and Development
- Parasites and Host Interactions
- Gut microbiota and health
- SARS-CoV-2 and COVID-19 Research
- Pediatric health and respiratory diseases
- Indigenous Studies and Ecology
- Viral gastroenteritis research and epidemiology
- Indigenous Health and Education
- Parasite Biology and Host Interactions
- Epilepsy research and treatment
- Neural Networks and Applications
- Regional Development and Innovation
- Reproductive System and Pregnancy
- Herpesvirus Infections and Treatments
- Neuroendocrine regulation and behavior
- Cytomegalovirus and herpesvirus research
- Nutritional Studies and Diet
- Historical and Environmental Studies
- Maternal and Perinatal Health Interventions
University of Washington
2018-2025
CHU Dijon Bourgogne
2025
Seattle University
2024
Washington Center
2023
University of California, Santa Barbara
2011-2021
Université de Limoges
2019
Yale University
2016-2018
Junta de Castilla y León
2005
University of California, San Francisco
1988
National Institutes of Health Clinical Center
1968
Parasitic worms influence human fecundity infect 2 billion people globally. Mostly, such infections are symptomless and individual worm burdens low. Blackwell et al. monitored the of Tsimane women in Bolivia. These have on average 10 children their lifetimes. However, if they had successive hookworm infections, lifetime births dropped to 7. Surprisingly, were chronically infested with roundworm, as many 12 children. effects may relate balance immune responses that different induce, rather...
Breast milk fatty acid (FA) composition varies greatly among individual women, including in percentages of the long-chain polyunsaturated FAs (LCPUFA) 20:4n-6 (arachidonic acid, AA) and 22:6n-3 (docosahexaenoic DHA), which are important for infant neurological development. It has been suggested that owing to wide variation LCPUFA low DHA Western diets, standards FA should be derived from populations consuming traditional diets. We collected breast samples Tsimane women at varying lactational...
Background The peak shift model predicts that the age-profile of a pathogen's prevalence depends upon its transmission rate, peaking earlier in populations with higher and declining as partial immunity is acquired. Helminth infections are associated increased immunoglobulin E (IgE), which may convey influence shift. Although studies have noted shifts helminths, corresponding total IgE not been investigated, nor has age-patterning carefully examined across populations. We test for differences...
Co-infection may affect transmission and recovery from infection, but remains an understudied element of disease ecology, particularly with regard to antagonism between parasites sharing a host. Helminth giardia infections are often endemic in the same populations both occupy small intestine; yet few studies have examined interactions these parasites. We report on helminth-giardia co-infections panel study forager-horticulturalists Bolivian lowlands. Parasites were identified faecal samples...
Poor sleep represents a central health disparity for people experiencing homelessness, and any intervention to alleviate the impacts of homelessness should aim improve sleep. We measured actimetry-based in homeless adults spending their nights four types shelters Seattle, WA, during summer winter. Homeless participants experienced more sleepless than housed both seasons. During sleeping nights, patterns similar subjects, but winter, duration was up 1.5 hours shorter. Similarly, quality,...
Background and aim We provide ethnographic, photovoice, psychosocial stress data (food water insecurity, potentially traumatic events, biomarkers) documenting the joys, hazards, stressors of adolescents engaging in climate-sensitive pastoralist livelihoods a global climate change hot spot. to holistically capture socio-environmental relationships characterised by sensitive forms precarity exacerbated change.
Memory deficits are a major burden in temporal lobe epilepsy (TLE), contributing to the impaired quality of life patients. Short- and long-term efficacy memory remediation TLE is still debated. The aim our study was assess short- cognitive program, COMETE (COgnitive Rehabilitation MEmory Temporal Epilepsy), targeting specifically episodic patients with TLE. In this prospective randomized single-blinded trial, from different French centers were randomly assigned 2:4 ratio, via...
Selective and neutral forces shape human microbiota assembly in early life. The Tsimane are an indigenous Bolivian population with infant care-associated behaviors predicted to increase mother-infant microbial dispersal. Here, we characterize community 47 infant-mother pairs from six villages, using 16S rRNA gene amplicon sequencing of longitudinal stool tongue swab samples. We find that consumption dairy products, vegetables, chicha (a fermented drink inoculated oral microbes) is associated...
Summary Objective To describe the mode of onset SCN 8A ‐related severe epilepsy in order to facilitate early recognition, and eventually treatment with sodium channel blockers. Methods We reviewed phenotype patients carrying a mutation gene, among multicentric cohort 638 prospectively followed by several pediatric neurologists. focused on way clinicians made diagnosis epileptic encephalopathy, very first symptoms, electroencephalography (EEG) findings , seizure types. genotypic/phenotypic...
Limited data are available regarding the balance of risks and benefits from human milk and/or breastfeeding during following maternal infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
The time-course of changes in the levels albumin, alpha-fetoprotein (AFP), alpha(1)-protease inhibitor (alpha(1)-antitrypsin), alpha(1)-acid glycoprotein, fetuin, haptoglobin, transferrin, IgG and major acute-phase protein (Pig-MAP) blood sera pigs during first days weeks life was investigated by quantitative radial immunodiffusion. serum newborn before suckling characterised a very low concentration total proteins (approximately 25 mg mL(-1)), albumin transferrin lack immunoglobulins. In...
Adaptive immune proteins in mothers' milk are more variable than innate across populations and subsistence strategies. These results suggest that the defenses shaped by a mother's environment throughout her life.
Measurements of polynucleotide sequence homologies have proved useful in investigating the relationships viruses, bacteria, plants, and animals.The techniques largely been restricted to examination organisms whose ge- netic information is contained double-stranded DNA.With few exceptions, nucleic acids mature RNA virions are single-stranded therefore not ame- nable hybridization.It has become clear, however, that cells infected with viruses also contain RNA's base-paired consist "plus"...
Premastication, the transfer of pre-chewed food, is a common infant and young child feeding practice among Tsimane, forager-horticulturalists living in Bolivian Amazon. Research conducted primarily with Western populations has shown that infants harbor distinct oral microbiota from their mothers. which less these populations, may influence colonization maturation microbiota, including via transmission pathogens. We collected premasticated food saliva samples Tsimane mothers (9-24 months age)...
Interregional encounters frequently result in dietary, health, and cultural changes for participating groups. This paper investigates the patterns pathways of dietary change among Mulia Dani highland western New Guinea, who at time data collection had been contact with Christian missionaries global food market 29 years. We explore three lines data: preferences (from survey responses), oral health (indicated by percentage carious missing teeth), composition stable isotope ratios [δ13C δ15N]...