A5007397610- Maternal and fetal healthcare
- Intraocular Surgery and Lenses
- Corneal Surgery and Treatments
- Cancer Immunotherapy and Biomarkers
- Genomic variations and chromosomal abnormalities
- Cardiovascular Issues in Pregnancy
- Chromosomal and Genetic Variations
- Pregnancy-related medical research
- Ferroptosis and cancer prognosis
- Glaucoma and retinal disorders
- Cancer-related molecular mechanisms research
- Advanced biosensing and bioanalysis techniques
- Retinal Development and Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Medical Research and Treatments
- Cancer, Hypoxia, and Metabolism
- Complement system in diseases
- Retinal Diseases and Treatments
- Renal Diseases and Glomerulopathies
- Sepsis Diagnosis and Treatment
- Bacterial Identification and Susceptibility Testing
- Hip and Femur Fractures
- Neurological Complications and Syndromes
- Genomics and Phylogenetic Studies
- Lung Cancer Treatments and Mutations
Hebei Normal University
2025
The Cancer Treatment Center
2025
Peking University People's Hospital
2018-2024
Peking University
2018-2024
Daqing Oilfield General Hospital
2024
Chinese People's Liberation Army
2024
Shenyang Pharmaceutical University
2020-2024
Chinese General Hospital College of Nursing and Liberal Arts
2024
Changchun University of Science and Technology
2024
Yangzhou University
2023
Prior studies demonstrate that hypoxia inducible factor subtype 1α (HIF-1α) in retinal tissues is involved development of diabetic retinopathy (DR). In this report, we particularly examined the role played by mammalian target rapamycin (mTOR) regulating expression HIF-1α and its downstream pathway, namely vascular endothelial growth (VEGF).Streptozotocin (STZ) was systemically injected to induce hyperglycemia rats. ELISA Western Blot analysis were employed determine levels VEGF as well mTOR...
A novel atmospheric pollutant transport quantification model (APTQM) has been developed to analyze and quantify cross-regional air pathways fluxes. The integrates high-resolution numerical simulations, Geographic Information System (GIS) capabilities, advanced statistical evaluation metrics with boundary pixel decomposition methods effectively characterize complex dynamics while ensuring computational efficiency. To evaluate its performance, the was applied a representative winter pollution...
The Taihang Mountains serve as a critical geographical barrier in northern China, delineating two major 2.5-micrometer particulate matter (PM2.5) pollution hotspots the Beijing–Tianjin–Hebei region and Fenwei Plain. This study examines underlying mechanisms interregional dynamic transport pathways of severe PM2.5 event that occurred urban agglomerations Central (CTHM) from 8–13 December 2021. WRF-HYSPLIT simulation was employed to analyze broader range potential sources pathways....
A cathode-anode bipolar electrochemiluminescence (ECL) strategy on multisite recognition for highly conservative gene motifs is anticipated to anchor the >200 nt-long polynucleotide chain precise quantification. Herein, lncRNA-HOTAIR sequences in NCBI database, derived from four different species (Homo sapiens, Mus musculus, Pan troglodytes, Canis lupus familiaris), were blasted online confirm three-segment exon motif texts (abbreviated as 1, 2 and 3), whose complementary artfully designed...
Objective: To investigate the independent risk factors, outcomes and genotypes associated with carbapenem-non-susceptible K. pneumoniae bloodstream infections (BSIs) in northern China from 2014 to 2016.Methods: Over a three-year period, total of 289 BSI patients were identified. Medical records extracted obtain clinical information. Polymerase chain reactions (PCRs) performed analyse multilocus sequence typing (MLST) types, Klebsiella carbapenemase (KPC) metallo-β-lactamases (MBL) genes, for...
Abstract Aggredation‐induced electrochemiluminescence (AIECL) promises an efficient strategy for synthesize highly luminescent emitter and co‐reactant ECL analysis, however, rational control of electrogenerated emission intensity is still challenging. The low electroconductivity amorphous molecular configuration are intrinsic bottleneck. This work reveals the impact polyvinyl pyrrolidone backbone regulated silver nanocrystallines (AgNCs/PVP) on cathode AIECL properties in near infrared...
Precise segmentation of chromosome in the real image achieved by a microscope is significant for karyotype analysis. The usually pixel-level classification task, which considers different instances as classes. Many instance methods predict Intersection over Union (IoU) through head branch to correct confidence. Their effectiveness based on correlation between tasks. However, none these consider input and output Herein, we propose network regression correction. First, adopt two branches...
Esophageal cancer (EC) is a common malignant tumor of the digestive system with high mortality and morbidity. Current evidence suggests that immune cells molecules regulate initiation progression EC. Accordingly, it necessary to identify immune-related genes (IRGs) affecting biological behaviors microenvironmental characteristics EC.Bioinformatics methods, including differential expression analysis, Cox regression, infiltration prediction, were conducted using R software analyze Gene...
Background. Geiparvarin (GN) is a natural compound with anticancer activity. However, the effect of GN on osteosarcoma (OS) and mechanism are still unclear. Methods. Cell viability was measured by MTT assay. Invasion migration were transwell The miRNAs, genes, signaling pathways affected confirmed whole-genome sequencing bioinformatics analysis. expression level mRNA protein qRT-PCR western blot. Animal experiment performed for confirming side in vivo. Results. Our results show that...
To investigate the clinical characteristics and predictors of mortality in patients with candidemia intensive care unit (ICU).The admitted to ICU Peking University People's Hospital from January 2010 December 2017 were enrolled. The general data, indicators related Candidia infection prognosis collected, characteristics, candidiasis analyzed. Patients divided into death group survival according hospital status. differences each index compared between two groups. independent risk factors...
Multidrug resistance of non‑small cell lung cancer (NSCLC) is a common clinical problem, which one the main reasons leading to failure chemotherapy. Therefore, how overcome or prevent drug has become hot and difficult issue in research. The present study was designed investigate expression patterns, functions underlying mechanisms MUC1 regulating paclitaxel‑resistant line A549/PR NSCLC. RT‑qPCR western blot performed determine mRNA protein level, respectively. CCK‑8 conducted viability...
Introduction. LN is an important complication affecting the prognosis of SLE. We retrospectively analysed influence thrombotic microangiopathy (TMA) on LN, identified risk factors TMA in and renal failure LN-TMA, evaluated availability plasmapheresis. Methods. After balancing epidemiological characteristics pathological types between groups, 127 patients (LN-TMA:42, LN:85) were included. consulting medical records followup data, we used corresponding statistical methods, such as chi-squared...
To the Editor: Sepsis is a clinical syndrome characterized by life-threatening organ dysfunction caused dysregulated host response to infection. Early intervention with antibiotics, intravenous fluids, and other supportive measures can significantly improve chances of recovery. For every hour delay in diagnosing treating patients septic shock, there 7.6% increase mortality rate.[1] Despite advances diagnostic technology, clinicians are still unable detect origin sepsis approximately...