A5020269074- Metal-Organic Frameworks: Synthesis and Applications
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Polyoxometalates: Synthesis and Applications
- Magnetism in coordination complexes
- Metal complexes synthesis and properties
- RNA modifications and cancer
- Advanced Nanomaterials in Catalysis
- Insect-Plant Interactions and Control
- RNA Research and Splicing
- MicroRNA in disease regulation
- Plant Stress Responses and Tolerance
- Cancer-related molecular mechanisms research
- Autophagy in Disease and Therapy
- Lung Cancer Treatments and Mutations
- Crystallography and molecular interactions
- Plant-based Medicinal Research
- Plant responses to water stress
- Tendon Structure and Treatment
- Wnt/β-catenin signaling in development and cancer
- Cellular Mechanics and Interactions
- Microtubule and mitosis dynamics
- Postharvest Quality and Shelf Life Management
- Circular RNAs in diseases
- Cancer Cells and Metastasis
Kunming University
2015-2025
Yunnan Center for Disease Control And Prevention
2018-2019
State Key Laboratory of Rice Biology
2014
Zhejiang University
2011-2014
China National Rice Research Institute
2011-2014
Ethylene responsive factors (ERFs) are a large family of plant-specific transcription that involved in the regulation plant development and stress responses. However, little to nothing is known about their role herbivore-induced defense. We discovered nucleus-localized ERF gene rice (Oryza sativa), OsERF3, was rapidly up-regulated response feeding by striped stem borer (SSB) Chilo suppressalis. Antisense over-expression OsERF3 revealed it positively affects transcript levels two...
Oxylipins produced by the 13-lipoxygenase (LOX) have been reported to play an important role in plant defense responses herbivores. Yet, of oxylipins 9-LOX pathway this process remains largely unknown. Here we cloned a gene encoding chloroplast-localized 9-LOX, Osr9-LOX1, from rice. Transcriptional analysis revealed that herbivore infestation, mechanical wounding and jasmonic acid (JA) treatment either repressed or did not enhance level Osr9-LOX1 transcripts at early stages but later stages,...
Gastric cancer (GC) is one of the most common cancers worldwide and thus a global burden. Here, we focused on novel circular RNA hsa_circ_0092306 explored potential molecular mechanism to provide new target for insights into GC treatment. The GEO microarray was mined analyzed with R software. Sanger sequencing RNase assay were applied verify identification hsa_circ_0092306. Quantitative real-time PCR western blot performed measure mRNA protein levels. Pull-down luciferase reporter assays...
Gastric cancer (GC) is one of the major global health problems, especially in Asia. Nowadays, long non-coding RNA (lncRNA) has gained significant attention current research climate such as carcinogenesis. This desires to explore mechanism Prader–Willi region non-protein coding 1 (PWRN1) on regulating GC process. Differentially expressed lncRNAs tissues were screened out through microarray analysis. The and protein expression level detected by quantitative real-time PCR (qRT-PCR) Western...
Abstract Objective This study aims to investigate the effect of polo‐like kinase 1 ( PLK1 ) inhibition on cisplatin (DDP)‐resistant gastric cancer (GC) cells. Methods: The transcriptional level was measured by quantitative reverse‐transcription polymerase chain reaction. Expressions and its downstream mediators as well autophagy‐related protein LC3 I/LC3 II were detected western blot. An 3‐(4,5‐Dimethylthiazol‐2‐yl)‐2,5‐diphenyltetrazolium bromide (MTT) assay 5‐ethynyl‐2′‐deoxyuridine...
Background Breast cancer is the leading cause of cancer‐related death in world, and it great value to reveal molecular mechanisms breast progression develop new therapeutic targets. Methods Transwell assay used analyze migration invasion cells. Real‐time PCR western blotting are applied detect expression levels epithelial–mesenchymal transition markers key members Wnt/β‐catenin PI3K/AKT signaling pathways. Results Manganese‐12 acetate (Mn12Ac) significantly inhibited MCF7 MDA‐MB‐231 Western...
Introduction: Hub genes related to the development of gastric cancer (GC) were identified based on bioinformatics methods. This study aimed identify GC hub genes, explore expression in and their correlation with prognosis, so as provide strategies for diagnosis targeted therapy. Methods: Two messenger RNA (mRNA) microarray datasets downloaded from GEO database. These data combined TCGA database obtain common DEGs between tissues normal tissues. GO KEGG pathway enrichment analysis was...
Lung cancer is the leading cause of global cancer-associated mortality, therefore it important to reveal molecular mechanisms lung progression and develop novel therapeutic targets. The results present study identified that manganese-12 acetate (Mn12Ac) was able significantly inhibit migration invasion A549 cells. Western blotting demonstrated treatment with Mn12Ac upregulate E-cadherin, downregulate N-cadherin vimentin. It also by a quantitative polymerase chain reaction analysis reduce...
Reactions of NaH2AsO4 with C-type polyanion precursor lead to a new compound, (NH4)15[As2Fe6Mo22O85AsO2(OH)2]·31.5H2O (1). Compound 1 was characterized by elemental analysis, infrared spectra, thermogravimetric and single-crystal X-ray diffraction. Structural analysis reveals that AsO2(OH)2− asymmetrically decorated the POM framework, constituting first inorganic anion decorating POM. AC measurements frequency-dependent χ′′ below 5 K indicated slow magnetization relaxation in 1, resembling...
Abstract The new supramolecular compound [Fe 2 (AsMo 7 O 27 ) ](H en) (NH 4 8 ·6H ( 1 (en = ethylenediamine) has been synthesized in aqueous solution and characterized by elemental analysis, thermal single crystal X-ray diffraction. structural analysis revealed that represents the first example of a polyoxometalate-based sandwich-type hybrid constructed from hexalacunary building blocks. Owing to presence ethylenediammonium cations, ] 12– units are stabilized multiple circular hydrogen bonds...
A new sandwich-type transition metal complex based on tungstobismuthates and 1-methylimidazole ligands Na7(mim)2[{Na(H2O)2}3{CoII(mim)}3(BiIIIWVI9O33)2]·9H2O (1) (mim = 1-methylimidazole) has been successfully isolated in aqueous solution. The composition structure were established by the single crystal X-ray diffraction analysis, elemental IR spectroscopy. Single-crystal TG analyses indicate that compound 1 consists of two tri-vacant [α-B-BiIIIWVI9O33]9- units linked through three cobalt...
Abstract C 22 H 28 Mn 2 N 8 O 6 , triclinic, P 1̅ (no. 2), a = 7.2827(15) Å, b 8.6433(17) c 11.410(2) α 98.58(3)°, β 96.15(3)°, γ 107.67(3)°, V 667.8(2) Å 3 Z 1, R gt ( F ) 0.0414, wR ref 0.0972, T 293(2) K.
Abstract C 20 H 24 MnClN 2 O 4 , triclinic, P 1̅ (no. 2), a = 7.9912(8) Å, b 11.8174(9) c 12.7781(15) α 112.855(9)°, β 97.649(9)°, γ 91.215(7)°, V 1098.6(2) Å 3 Z 2; R gt ( F ) 0.0491, wR ref 0.1319, T 250(2) K.
Abstract C 16 H 12 Cl 2 CuN O , orthorhombic, Pbca (no. 61), a = 12.8449(5) Å, b 12.5266(6) c 19.0540(11) V 3065.8(3) Å 3 Z 8, R gt ( F ) 0.0423, wR ref 0.1164, T 173(2) K.
Objective To explore Impact and mechanism of PMs-3 to epithelial mesenchymal transformation (EMT) non-small cell lung cancer (NSCLC) line A549. Methods Nanocomposite structure synthetized by our team was utilized on human NSCLC A549 normal pulmonary BEAS-2B with concentrations 0, 20, 40, 60, 80, 100, 120 nmol/L for 48 h. Methyl thiazol tetrazolium (MTT) assay employed detect the effect cells. Wound Transwell chamber were used test migration invasion EMT related genes detected real...