A5067150820- Multiple Sclerosis Research Studies
- Peripheral Neuropathies and Disorders
- Parkinson's Disease Mechanisms and Treatments
- Neurological disorders and treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Intracranial Aneurysms: Treatment and Complications
- Neurogenesis and neuroplasticity mechanisms
- Immune Response and Inflammation
- Healthcare professionals’ stress and burnout
- Antifungal resistance and susceptibility
- Autism Spectrum Disorder Research
- Psoriasis: Treatment and Pathogenesis
- Hereditary Neurological Disorders
- Long-Term Effects of COVID-19
- Autoimmune Neurological Disorders and Treatments
- Patient-Provider Communication in Healthcare
- Acute Ischemic Stroke Management
- Immunotherapy and Immune Responses
- Rheumatoid Arthritis Research and Therapies
- Parkinson's Disease and Spinal Disorders
- Genetics and Neurodevelopmental Disorders
- Myasthenia Gravis and Thymoma
- Cytokine Signaling Pathways and Interactions
- Health, psychology, and well-being
- Health Systems, Economic Evaluations, Quality of Life
Hospital de Cruces
2005-2024
BioCruces Health research Institute
2022
Osakidetza
2005-2022
Országos Korányi Tbc és Pulmonológiai Intézet
2013
Universitat de Barcelona
2013
Medical University of Vienna
2013
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2013
University of the Basque Country
2005
To (1) determine the value of recently proposed criteria neuromyelitis optica (NMO) spectrum disorder (NMOSD) that unify patients with NMO and those limited forms (NMO/LF) aquaporin-4 immunoglobulin G (AQP4-IgG) antibodies; (2) investigate clinical significance serologic status in NMO.This was a retrospective, multicenter study 181 fulfilling 2006 (n = 127) or NMO/LF AQP4-IgG 54). myelin oligodendrocyte glycoprotein (MOG-IgG) antibodies were tested using cell-based assays.Patients mainly...
Twelve patients with Parkinson disease and psychosis were included in an open-label 12-week trial of ziprasidone. Two withdrew from the treatment because adverse effects. The remaining 10 reported a significant improvement psychiatric symptoms. Altogether, there was no deterioration motor symptoms (UPDRS III score: basal 40.4 ± 11, 1, first month 41.1 10.8; final visit, 37.7 13.3). (20%) suffered slight another patient gait. No analytic alterations or serious effects that could limit use...
Neuromyelitis optica spectrum disorder (NMOSD) is associated with a reduced health-related quality of life (HRQoL). The purpose this study was to describe the impact NMOSD on HRQoL from patients' perspective and its relationship other disease factors. An observational, cross-sectional conducted at 13 neuroimmunology clinics in Spain. Patients diagnosis (2015 Wingerchuk criteria) were included. 29-item Multiple Sclerosis Impact Scale (MSIS-29) used assess HRQoL. Different questionnaires...
Intronic single-nucleotide polymorphisms (SNPs) in the ANKRD55 gene are associated with risk for multiple sclerosis (MS) and rheumatoid arthritis by genome-wide association studies (GWAS). The alleles have been linked to higher expression levels of neighboring IL6ST (gp130) CD4+ T lymphocytes healthy controls. biological function ANKRD55, its role immune system, cellular sources other than remain uncharacterized. Here, we show that monocytes gain capacity express during differentiation...
Background: The frequency of cognitive impairment (CI) reported in neuromyelitis optica spectrum disorder (NMOSD) is highly variable, and its relationship with demographic clinical characteristics poorly understood. We aimed to describe the profile NMOSD patients, analyse differences according their serostatus; furthermore, we assess between cognition, characteristics, other aspects linked health-related quality life (HRQoL). Methods: This cross-sectional study included 41 patients (median...
Perception of stigma was associated with low self-esteem, psychological problems, and decreased health-seeking behavior among patients different neurological disorders. The purpose this study to assess stigmatization its impact in neuromyelitis optica spectrum disorder (NMOSD).A non-interventional conducted at thirteen neuroimmunology clinics Spain. Patients a diagnosis NMOSD (2015 Wingerchuk criteria) were included. 8-item Stigma Scale for Chronic Illness (SSCI-8), the Expanded Disability...
Introduction and objective Limited information is available on how neurologists make therapeutic decisions in neuromyelitis optica spectrum disorder (NMOSD), especially when new treatments with different mechanisms of action, administration, safety profile are being approved. Decision-making can be complex under this uncertainty may lead to inertia (TI), which refers lack treatment initiation or intensification goals not met. The study aim was assess neurologists’ TI NMOSD. Methods An...
Caring for patients suffering from a cerebrovascular diseases requires large quantity of resources which must be optimised. The aim this study is to analyse the management stroke in tertiary care hospital.All admissions with diagnosis were analysed retrospectively year 2003. Length stay, computed tomography Emergency Room, origin, previous during last year, presence vascular risk factors, subtype, complications and mortality admission destination when discharged hospital, all recorded.936...
The study's aim was to assess the importance given by neurologists bodily functions of patients with neuromyelitis optica spectrum disorder (NMOSD).
Background The assessment of self-reported outcomes in neuromyelitis optica spectrum disorder (NMOSD) is limited by the lack validated disease-specific measures. SymptoMScreen (SyMS) a patient-reported questionnaire for measuring symptom severity different domains affected multiple sclerosis (MS), but has not been thoroughly evaluated NMOSD. aim this study was to assess psychometric properties SyMS sample patients with Methods A non-interventional, cross-sectional adult subjects NMOSD...
To assess the perception of stigma and its impact in neuromyelitis optica spectrum disorders (NMOSD).