A5067487266- Cancer survivorship and care
- Lung Cancer Research Studies
- Lung Cancer Treatments and Mutations
- Cancer Treatment and Pharmacology
- Hepatocellular Carcinoma Treatment and Prognosis
- Pain Management and Opioid Use
- Clinical practice guidelines implementation
- Lung Cancer Diagnosis and Treatment
- Childhood Cancer Survivors' Quality of Life
- Clinical Reasoning and Diagnostic Skills
- Palliative Care and End-of-Life Issues
- Inflammatory mediators and NSAID effects
- PI3K/AKT/mTOR signaling in cancer
- Health Systems, Economic Evaluations, Quality of Life
- Cancer, Hypoxia, and Metabolism
- Angiogenesis and VEGF in Cancer
- Musculoskeletal pain and rehabilitation
- Chemotherapy-related skin toxicity
- Health Sciences Research and Education
- Global Cancer Incidence and Screening
- Shoulder Injury and Treatment
- Peptidase Inhibition and Analysis
- Central Venous Catheters and Hemodialysis
- Digital Mental Health Interventions
- Genomics and Rare Diseases
Istituti di Ricovero e Cura a Carattere Scientifico
2023-2024
University of Rome Tor Vergata
2022-2024
European Institute of Oncology
2007-2024
Agostino Gemelli University Polyclinic
2024
Ripamonti
2023
Mylan (Switzerland)
2016
PARI (Germany)
2016
University of Milan
2016
Istituto Nazionale di Statistica
2012
Vita-Salute San Raffaele University
2011
Background: Arthroscopic rotator cuff repair generally provides satisfactory results including decreased shoulder pain and improved motion. Unfortunately, imaging studies demonstrate that the retear rate associated with available arthroscopic techniques may be high. The purpose of this study was to evaluate clinical magnetic resonance (MRI) without use platelet-leukocyte membrane in patients a large posterosuperior tear. Methods: Eighty consecutive full-thickness tear were enrolled. All...
NGR-hTNF exploits the tumor-homing peptide asparagine-glycine-arginine (NGR) for selectively targeting TNF-α to an aminopeptidase N overexpressed on cancer endothelial cells. Preclinical synergism with cisplatin was displayed even at low doses. This study primarily aimed explore safety of low-dose combined in resistant/refractory malignancies. Secondary aims included pharmacokinetics (PKs), pharmacodynamics, and activity.NGR-hTNF escalated using a doubling-dose scheme (0.2-0.4-0.8-1.6...
Chronic pain (CP) and its management are critical issues in the care pathway of patients with breast cancer. Considering complexity CP experience cancer, international scientific community has advocated identifying cutting-edge approaches for management. Recent advances field health technology enable adoption a novel approach to by developing integrated ecosystems mobile apps.The primary end point this pilot study is evaluate patients' usability at 3 months new digital technological...
Abstract Few resources are available to quantify clinical trial–associated workload, needed guide staffing and budgetary planning. The aim of the study is describe a tool measure trials nurses' workload expressed in time spent complete core activities. Clinical nurses drew up list nursing activities, integrating results from literature searches with personal experience. final 30 activities were timed for each research nurse by an outside observer during daily practice May June 2014. Average...
Chronic pain is one of the most common and critical long-term effects breast cancer. Digital health technologies enhance management chronic by monitoring physical psychological status supporting self-management patient treatment decisions throughout clinical pathway.
In 2016, the International Consortium for Health Outcomes Measurement (ICHOM) defined an international consensus recommendation of most important outcomes lung cancer patients. The European Observatory (H2O) initiative aimed to develop updated patient-centered core outcome set (COS) cancer, capture patient perspective impact and (novel) treatments using a combination patient-reported (PRO) instruments clinical data as means drive value-based health-care.An international, expert team...
Abstract Aim Patients' death or adverse events appear to be associated with poor healthcare decision‐making. This might due an inability have adequate representation of the problem connections among problem‐related elements. Changing how a is formulated can reduce biases in clinical reasoning. The purpose this article explore possible contributions psychoneuroendocrinoimmunology (PNEI) and psychology reasoning decision‐making (PRDM) support new nursing theoretical frame. Design Discursive...
Normal saline is considered a safe alternative for heparin as locking solution in totally implantable venous access devices. The incidence rate of partial occlusion with the use normal (easy injection, impossible aspiration) estimated at 4%.The aim this study was to investigate determinants occlusions and maintenance positive pressure catheter.We enrolled 218 patients different solid tumors who underwent pharmacologic treatment through port frequencies: from once every week least month....
Introduction: We describe the clinical features, outcome and incidence of druggable targets lung cancers in patients ≤40 years old. Materials & methods: Young were compared with two other groups (41–64 ≥65 years). Neuroendocrine tumors, adenocarcinoma non-adenocarcinoma/unspecified non-small-cell cancer analyzed separately. Molecular characteristics evaluated a subset young patients. Results: Of 2847 cancer, 100 The group contained more women, never-smokers presenting advanced disease....
The nursing minimum data set (NMDS) was created in 1977 the United States to collect uniform standardised that could be comparable among different areas or patients. So far, literature, an NMDS oncology setting has not yet been described. Considering (ONMDS), which chosen define this tool regarding cancer patient care?At European Institute of Oncology (IEO), 20 experienced nurses representing surgical, medical, and critical participated a record working group. All followed educational course...
<i>Background:</i> α-Interferon, thalidomide and celecoxib inhibit tumour angiogenesis by differing mechanisms. <i>Patients Methods:</i> In a randomized phase II trial to assess tolerability safety, we assigned patients with advanced slow-growing solid tumours 1 of 6 two- or three-drug combinations: α-interferon 0.5 million IU b.i.d., (100 mg b.i.d. reduced 100 daily), (400 daily 200 mg). Circulating endothelial cells progenitors (CECs, CEPs) vascular growth factor...
2006 Background: QT interval prolongation associated with “torsades de pointes” (TdP) has been a common cause of withdrawal from the market for several promising drugs. We determined degree in patients treated within phase I study thioxanthone derivative known to have arrhythmogenic potential. Methods: Clinical data and serial ECGs 31 advanced tumors who received 86 courses investigational drug were prospectively reviewed. The administered intravenously over 24 hours every 3 weeks. Patients...
Aims Endoscopic ultrasound (EUS) placement of Lumen-Apposing Metal Stent (LAMS) represents a minimally invasive treatment for Walled-off pancreatic necrosis (WOPN). Further endoscopic necrosectomy procedures (EN) may be required in subset patients, mostly order to achieve infection control. The possibility an early identification the subjects requiring EN therefore represent valuable clue management patients with WOPN.
. How clinical trials have changed in the last 25 years. Although are not most common research design used by nurses, it is useful to reflect on how study designs, even classic such as trials, change technologies and knowledge progress. The main changes general setting of ith "new" trial designs breafly described.
<sec> <title>BACKGROUND</title> Chronic pain (CP) and its management are critical issues in the care pathway of patients with breast cancer. Considering complexity CP experience cancer, international scientific community has advocated identifying cutting-edge approaches for management. Recent advances field health technology enable adoption a novel approach to by developing integrated ecosystems mobile apps. </sec> <title>OBJECTIVE</title> The primary end point this pilot study is evaluate...