A5004716597- Acute Myeloid Leukemia Research
- Lymphoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Cutaneous lymphoproliferative disorders research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Chronic Myeloid Leukemia Treatments
- Multiple Myeloma Research and Treatments
- Viral-associated cancers and disorders
- Hemoglobinopathies and Related Disorders
- RNA modifications and cancer
- Histone Deacetylase Inhibitors Research
- COVID-19 Clinical Research Studies
- Eosinophilic Disorders and Syndromes
- Pneumocystis jirovecii pneumonia detection and treatment
- Protein Degradation and Inhibitors
- Fungal Infections and Studies
- Cancer-related molecular mechanisms research
- Long-Term Effects of COVID-19
- Hematological disorders and diagnostics
- Sarcoma Diagnosis and Treatment
- Acute Lymphoblastic Leukemia research
- SARS-CoV-2 and COVID-19 Research
- CNS Lymphoma Diagnosis and Treatment
- T-cell and Retrovirus Studies
- Complement system in diseases
National and Kapodistrian University of Athens
2015-2025
University General Hospital Attikon
2015-2024
National Technical University of Athens
2023
Children's Hospital of Philadelphia
2017-2022
University of Cambridge
2020-2022
National Institute for Health Research
2022
Hellenic Open University
2022
Drexel University
2022
Hellenic Oncology Research Group
2018-2020
Albert Einstein College of Medicine
2015
Unraveling the pathophysiology of COVID-19 disease is crucial importance for designing treatment. The purpose this study to investigate effects on erythrocytes (RBCs) and correlate findings with severity.
Background/Objectives: There are limited data regarding immunohistochemical profiling of immune cells in bone marrow trephine biopsies patients with high-risk myelodysplastic syndromes (HR-MDS). Methods: We sought to objectively quantify, the use digital pathology, density (cells/mm2) prominent adaptive immunity cell populations sixty-four (64) HR-MDS receiving 5-Azacytidine. focused on CD3(+) T cells, CD8(+) cytotoxic (Tc), helper (Th), Foxp3(+) regulatory (Tregs), CD20(+) B-cells and...
Background Lenalidomide improves erythropoiesis in patients with low/intermediate-1 risk myelodysplastic syndrome and interstitial deletion of the long arm chromosome 5 [del(5q)]. The aim this study was to explore effect lenalidomide treatment on reserves functional characteristics bone marrow hematopoietic progenitor/precursor cells, stromal cells peripheral blood lymphocytes del(5q).Design Methods We evaluated number clonogenic potential erythroid/myeloid/megakaryocytic progenitor using...
MicroRNA-155-5p (miR-155-5p) is a proinflammatory, oncogenic miRNA, involved in various physiological processes, including hematopoiesis, immunity, inflammation, and cell lineage differentiation. It regulates important transcription factors, such as E2F2, hypoxia-inducible factor 1 (HIF1), FOXO3. Recently, the dysregulation of miR-155-5p expression has been linked to chronic lymphocytic leukemia (CLL) pathogenesis. In this research study, we investigated potential diagnostic prognostic value...
Although most patients with classical Hodgkin's lymphoma (CHL) are cured, a significant minority refractory to treatment. The investigation of biological markers could improve the predictive capacity clinical staging systems. aim our study was detect B-cell differentiation and transcription factors in CHL order define subgroups different histogeneses prognoses.We evaluated 107 cases for BCL6, CD79a, MUM1/IRF4 BOB.1, OCT.2 expression by immunohistochemistry. Statistical analysis performed...
We determined the Human Blood Index (HBI) of malaria mosquito vectors in Equatorial Guinea. used a polymerase chain reaction (PCR)-based methodology to identify blood meal sources engorged mosquitoes. observed high HBI values, indicating that these are highly anthropophilic despite intensive intradomicillary application residual insecticides. Our results suggest estimating can be relatively simple and easy way evaluate efficacy antimalaria interventions where an diversion non-human hosts may...
Cerebral malaria (CM) remains a significant cause of morbidity and mortality in children sub-Saharan Africa. CM has been associated with increased brain volume, seen on neuroimaging studies. To examine the potential role blood metabolites inflammatory mediators volume Malawian CM, an association study was performed between plasma metabolites, cytokine levels phospholipase A2 (PLA2) activity volume. The metabolomics analysis demonstrated arachidonic acid other lysophospholipids to be...
Mycosis fungoides (MF) is an indolent cutaneous lymphoma with excellent prognosis at early stages and much poorer outcome during disease progression. Old age, male sex folliculotropism have been proposed as relevant prognostic factors; however, their exact effect remains debatable.To evaluate MF indicators survival rates in a Greek population.Prognostic variables affecting were studied 473 patients diagnosed treated by two academic referral centres Greece. Kaplan-Meier estimates used to...