A5056534275- Extracellular vesicles in disease
- Gut microbiota and health
- Bacterial Infections and Vaccines
- Clostridium difficile and Clostridium perfringens research
- Adolescent and Pediatric Healthcare
- Inflammasome and immune disorders
- Enterobacteriaceae and Cronobacter Research
- Nanoplatforms for cancer theranostics
- Probiotics and Fermented Foods
University of Oulu
2022-2025
Gut microbiome–derived nanoparticles, known as bacterial extracellular vesicles (bEVs), have garnered interest promising tools for studying the link between gut microbiome and human health. The diverse composition of bEVs, including their proteins, mRNAs, metabolites, lipids, makes them useful investigating diseases such cancer. However, conventional approaches alone may not be accurate in deciphering host–gut communication. In clinical research, there is a gap knowledge on role bEVs solid...
ABSTRACT Extracellular vesicles (EVs), nanoparticles secreted by both gram-negative and gram-positive bacteria, carry various biomolecules cross biological barriers. Gut microbiota-derived EVs are currently being investigated as a communication mechanism between the microbiota host. Few clinical studies, however, have gut EVs. Here, we show that machine learning models were able to accurately distinguish respective EV samples according their taxonomic composition within each data set (area...