A5041914870- Oral health in cancer treatment
- Cancer survivorship and care
- Hematopoietic Stem Cell Transplantation
- Head and Neck Cancer Studies
- Sport and Mega-Event Impacts
- Childhood Cancer Survivors' Quality of Life
- Palliative Care and End-of-Life Issues
- Cancer Diagnosis and Treatment
- Family Support in Illness
- Oral Health Pathology and Treatment
- Salivary Gland Disorders and Functions
- Mesenchymal stem cell research
- Complementary and Alternative Medicine Studies
- Family and Patient Care in Intensive Care Units
- Health Sciences Research and Education
- Pain Management and Opioid Use
- Health Systems, Economic Evaluations, Quality of Life
- Mentoring and Academic Development
- Interprofessional Education and Collaboration
- Nausea and vomiting management
- Pain Management and Placebo Effect
- Higher Education and Employability
- Mathematical Biology Tumor Growth
- Autoimmune and Inflammatory Disorders Research
- Palliative and Oncologic Care
Georgetown University
2014-2024
Georgetown University Medical Center
2021-2024
Uniformed Services University of the Health Sciences
2023-2024
National Institutes of Health
2002-2012
National Institute of Nursing Research
2006-2012
International Society for Heart and Lung Transplantation
2011
National Heart Lung and Blood Institute
2011
European Society for Blood and Marrow Transplantation
2011
Davidson College
2008
National Cancer Institute
2005-2006
The lack of standardized criteria for quantitative measurement therapeutic response in clinical trials poses a major obstacle the development new agents chronic graft-versus-host disease (GVHD). This consensus document was developed to address several objectives be used GVHD-related trials. proposed measures should practical use both by transplantation and nontransplantation medical providers, adaptable adults children, focused on most important GVHD manifestations. also give preference...
Abstract Objective To test the hypothesis that Antonovsky's concept of sense coherence (SOC) predicts stressful events, coping strategies, health status, and quality life (QoL) in a cohort postmenopausal women ( n = 131) with newly diagnosed primary or recurrent breast cancer. Methods Regression analyses longitudinal data at baseline through 6 months following cancer diagnosis examined relationships between SOC (13‐item version), daily assessment QoL (EORTC QLQ‐30). Results The findings...
objectives: The purpose of this study was to determine the influence fatigue, pain, and depression on health status in breast cancer patients who had completed adjuvant chemotherapy were scheduled for autologous bone marrow/peripheral blood stem cell transplant (AT). materials methods: A predictive, correlational design used. convenience sample 127 women with stages II, III, IV recruited. setting an urban National Cancer Institute‐designated comprehensive center located Eastern United...
Patients with breast cancer who undergo autologous bone marrow/peripheral blood stem cell transplantation (ABMT) cope not only a life-threatening medical treatment, but also multiple, interrelated symptoms including pain, fatigue, psychological distress, and nausea. The purpose of this study was to determine, in randomized controlled clinical trial, whether comprehensive coping strategy program (CCSP) effective significantly reducing nausea patients underwent ABMT. CCSP composed preparatory...
To determine the effects of sociodemographic variables, psychological distress, fatigue, and quality life (QOL) on burden care in primary caregivers patients with breast cancer undergoing autologous bone marrow transplantation (BMT).Descriptive, correlational, predictive.Urban National Cancer Institute-designated comprehensive center eastern United States.Convenience sample 102 caregivers.Participants completed data form, Piper Fatigue Scale, Beck Depression Inventory, State-Trait Anxiety...
The lack of standardized criteria for measuring therapeutic response is a major obstacle to the development new agents chronic graft-versus-host disease (cGVHD). National Institutes Health (NIH) consensus evaluating were published in 2006. We report results 4 consecutive pilot trials feasibility and estimating interrater reliability minimum detectable change these criteria. Hematology-oncology clinicians with limited experience applying NIH cGVHD (n = 34) participated 2.5-hour training...
Abstract Background This study aims to examine the effectiveness of a self‐management multimodal comprehensive coping strategy program (CCSP) on quality life (QOL) among breast cancer patients 1 year after treatment. Methods Patients ( n = 110) with stage II, III, or IV scheduled receive high dose chemotherapy and autologous hematopoietic stem cell transplantation were randomized either CCSP treatment control group. The intervention was taught 2 week before hospital admission reinforcement...
Oral chronic graft-versus-host disease (cGVHD) is a frequent, clinically significant sequela of allogeneic hematopoietic stem cell transplantation (HSCT). This study was designed to elucidate relationships among clinical characteristics oral cGVHD and related pain dryness, salivary proinflammatory cytokine interleukin (IL)-6 IL-1alpha concentrations, health-related quality life (HRQL). An understanding the correlates manifestations symptoms, such as fundamental development therapeutic...
PURPOSE Our purpose was to describe the prevalence and predictors of symptom function clusters related physical, emotional, social components general health-related quality life (HRQOL) in a population-based sample prostate cancer (PCa) survivors. METHODS Participants (N = 1,162) completed baseline survey at median 9 months after diagnosis ascertain co-occurrence eight functional domains that are common across all cancers not treatment-specific. We used latent profile analysis (LPA) identify...
Typical cancer research studies of health-related quality life (HRQOL) in the United States do not include country origin when examining race and ethnic group differences. This population-based, cross-sectional study used an innovative methodology to examine how self-reported racial groups, by origin, report differential HRQOL experiences after adjusting for clinical demographic characteristics, including socioeconomic status.Recruited from 4 registries California, Louisiana, New Jersey,...
Abstract Area-level socioeconomic status (SES) impacts cancer outcomes, such as stage at diagnosis, treatments received, and mortality. However, less is known about the relationship between area-level SES health-related quality of life (HRQOL) for survivors. To assess additive value data relative contribution area- individual-level estimating survivors’ HRQOL, we conducted a secondary analysis from population-based survey study survivors (the Measuring Your Health [MY-Health] Study)....
The purpose of this cross-sectional, correlational study was to describe stomatitis-related pain in women with breast cancer undergoing autologous hematopoietic stem cell transplant. hypotheses that significant, positive relationships would exist between oral and stomatitis, state anxiety, depression, alteration swallowing were tested. Stomatitis, sensory dimension pain, anxiety hypothesized most accurately predict overall intensity. Thirty-two recruited at 2 East Coast comprehensive...
Abstract Patients treated for head and neck cancer may experience impaired eating talking that affect their ability to undergo social activities. We conducted a secondary data analysis explore: 1) prevalence of perceived isolation, 2) association between isolation health-related quality life (HRQoL) in patients with cancer. Data were collected during clinical usefulness study the Electronic Patient Visit Assessment (ePVA), valid, reliable web-based patient-reported symptom measure The...
Clinical evidence suggests that patients with liver disease and HIV have poorer quality of life (QOL). Because little research exists to support this observation, study examined the relationships between people disorders their QOL. Cella's multidimensional (functional, social, emotional, physical) conceptualization QOL guided study. The sample included 80 participants HIV; 48.8% had chronic or permanent hepatitis. four dimensions significantly correlated QOL: functional, r = .329, p < .01;...