A5101452715- Heart Rate Variability and Autonomic Control
- ECG Monitoring and Analysis
- Heart rate and cardiovascular health
- Non-Invasive Vital Sign Monitoring
- EEG and Brain-Computer Interfaces
- Cardiovascular and exercise physiology
- Speech Recognition and Synthesis
- Radiomics and Machine Learning in Medical Imaging
- Endometrial and Cervical Cancer Treatments
- Cervical Cancer and HPV Research
- Cancer Immunotherapy and Biomarkers
- Ultrasound and Hyperthermia Applications
- Gastrointestinal disorders and treatments
- Infrared Thermography in Medicine
- Colorectal Cancer Surgical Treatments
- Disaster Response and Management
- RNA modifications and cancer
- Vagus Nerve Stimulation Research
- Functional Brain Connectivity Studies
- Cardiac electrophysiology and arrhythmias
- Viral Infections and Vectors
- Neural dynamics and brain function
- interferon and immune responses
- Colorectal Cancer Treatments and Studies
- Inflammatory Biomarkers in Disease Prognosis
Qinghai Provincial Peoples Hospital
2025
Bengbu Medical College
2013-2024
Shanxi Medical University
2024
Shanxi Academy of Medical Sciences
2024
State Key Laboratory of Natural Medicine
2024
China Pharmaceutical University
2024
Soochow University
2021-2024
First Affiliated Hospital of Soochow University
2021-2024
Komori (Japan)
2024
Aichi Cancer Center
2024
Entropy measures have been extensively used to assess heart rate variability (HRV), a noninvasive marker of cardiovascular autonomic regulation. It is yet be elucidated whether those entropy can sensitively respond changes balance and the responses, if there are any, consistent across different measures. Sixteen healthy subjects were enrolled in this study. Each subject undertook two 5-min ECG measurements, one resting seated position another while walking on treadmill at regular speed 5...
Background Laparoscopic total mesorectal excision (LaTME) is standard surgical methods for rectal cancer, and LaTME operation a challenging procedure. This study intended to use machine learning develop validate prediction models difficulty of in patients with cancer compare these models’ performance. Methods We retrospectively collected the preoperative clinical MRI pelvimetry parameter who underwent laparoscopic resection from 2017 2022. The was defined according scoring criteria reported...
Identifying prognostic factors by affordable tools is crucial for guiding gastric cancer (GC) treatments especially at earlier stages timing interventions. The autonomic function that clinically assessed heart rate variability (HRV) involved in tumorigenesis. This pilot study was aimed to examine whether nonlinear indices of HRV can be biomarkers GC severity. Sixty-one newly-diagnosed patients were enrolled. Presurgical serum fibrinogen (FIB), carcinoembryonic antigen (CEA), and carbohydrate...
In recent years, reports regarding stimulator of interferon genes (STING) and the progression colorectal cancer (CRC) have emerged rapidly, yet their association remains controversial. This research was aimed to provide an insight into prognostic biomarker therapeutic target significance STING in CRC.CRC Cell lines HCT116 SW480, as well 32 paired CRC specimens were chosen for this study. expressions examined by immunohistochemistry evaluate correlation with clinicopathological factors. Data...
Background The effectiveness of Sacituzumab Govitecan (SG) for metastatic triple-negative breast cancer (mTNBC) has been demonstrated. We aimed to evaluate its cost-effectiveness on mTNBC from the Chinese and United States (US) perspective. Methods A partitioned survival model was developed compare cost SG versus single-agent chemotherapy based clinical data ASCENT phase 3 randomized trial. Cost utility were obtained literature. incremental ratio (ICER) measured, one-way probabilistic...
The purpose of this study was to analyze the injury characteristics patients and therapeutic strategies for injured in last three big earthquakes China, so as provide a reference improvement emergency plans earthquakes. analysis based on data provided by Mianyang Central Hospital (MCH) from May 12th, 2008 September 26th, 2017. Microsoft EXCEL software used input, SPSS statistical analysis. A total 1,390 earthquake-related were hospitalized MCH. Most admitted hospital within first 2 weeks...
The acceleration and deceleration patterns in heartbeat fluctuations distribute asymmetrically, which is known as heart rate asymmetry (HRA). It hypothesized that HRA reflects the balancing regulation of sympathetic parasympathetic nervous systems. This study was designed to examine whether altered autonomic balance during exercise can lead changes. Sixteen healthy college students were enrolled, each student undertook two 5-min ECG measurements: one a resting seated position another while...
Cardiac autonomic modulation, assessed by heart rate variability (HRV), is associated with tumor pathogenesis and development as well invasion metastasis. This study aimed to examine this association in breast cancer (BC) patients. A total of 133 patients (average age 49.2years) BC or benign tumors were divided into three groups: group, early-stage advanced-stage group. About 5-min resting ECG was collected for the analysis linear nonlinear HRV parameters. Multiple logistic regression models...
To assess the diagnostic value of ultrasonography (US) for congenital small bowel atresia (SBA) in neonates and their sonographic characteristics.A retrospective analysis was performed 20 who were confirmed with SBA by operation from March 2014 to January 2019. All have been scanned US before surgery, no one underwent barium enema or upper gastrointestinal imaging prior US. Preoperation ultrasound characteristics about intestinal morphology contents collected, further summarize typical...
The measurement of heart rate variability (HRV) is the preferred method for assessing function autonomic nervous system (ANS). Traditional HRV detection requires an electrocardiogram (ECG) or photoelectric sensor. In this paper, we propose a new using rear smartphone camera as Video signals from fingertips 24 college students were acquired HTC M8d smartphone. ECG simultaneously recorded reference. video converted into single-frame image sequences over time. Each frame was transformed point...
Previous studies have shown that the predictive value of traditional linear (time domain and frequency domain) heart rate variability (HRV) for survival patients with advanced non-small cell lung cancer (NSCLC) is controversial. Nonlinear methods, based on concept complexity, been used to evaluate HRV, providing a new means reveal physiological pathological changes in HRV. This study aimed assess association between heartbeat complexity overall NSCLC. included 78 NSCLC (mean age: 62.0 ± 9.3...
The occurrence of lymph node metastasis (LNM) is one the critical factors in determining staging, treatment and prognosis cervical cancer (CC). Heart rate variability (HRV) associated with LNM patients CC. purpose this study was to validate feasibility machine learning (ML) models constructed preoperative HRV as a feature CC predicting LNM.
Background Lymph node metastasis (LNM) is an important prognostic factor for cervical cancer (CC) and determines the treatment strategy. Hematological indicators have been reported as being useful biomarkers prognosis of a variety cancers. This study aimed to evaluate feasibility machine learning models characterized by preoperative hematological predict LNM status CC patients before surgery. Methods The clinical data 236 with pathologically confirmed were retrospectively analyzed at...
The aim of this prospective study was to evaluate the association between heart rate variability (HRV) and overall survival lung cancer patients with brain metastases (LCBM).Fifty-six LCBM were enrolled in study. Five-minute electrocardiograms collected before time first radiotherapy. HRV analyzed quantitatively by using domain parameters, i.e., standard deviation all normal-normal intervals (SDNN) root mean square successive differences (RMSSD). Survival for defined as from date testing...
To investigate the value of pretreatment blood biomarkers combined with magnetic resonance imaging (MRI) in predicting efficacy neoadjuvant chemoradiotherapy (NCRT) patients locally advanced rectal cancer (LARC).This study involved LARC who received NCRT and subsequently underwent total mesenteric excision from June 2015 to 2021 at First Affiliated Hospital Soochow University. Patients incomplete courses therapy, comorbidities other malignancies or diseases that affect outcome, those...
Colon cancer is one of the most common malignant tumors, with high rates incidence and death. The tumor mutational burden (TMB), which characterized by microsatellite instability, has been becoming a powerful predictor can show behavior response to immunotherapy.In this study, we analyzed 437 mutation data colon samples obtained from Cancer Genome Atlas (TCGA) divided patients into low- high-TMB groups according TMB value. Then identified differentially-expressed genes (DEGs), conducted...
Background: Prior research suggests that autonomic modulation investigated by heart rate variability (HRV) might act as a novel predictive biomarker for cancer prognosis, such in breast and pancreatic cancer. It is not clear whether there correlation between prognosis patients with extensive-stage small cell lung (ES-SCLC). Therefore, the purpose of study was to examine association short-term HRV, deceleration capacity (DC) acceleration (AC) overall survival ES-SCLC. Methods: We recruited 40...
Background Prior research suggests that cardiovascular autonomic dysfunction might be an early marker of cardiotoxicity induced by antitumor treatment and act as predictor disease-related morbidity mortality. The impact thoracic radiotherapy on the parasympathetic sympathetic nervous systems, however, remains unclear. Therefore, this study aimed to evaluate short-term effects system, using deceleration capacity (DC), acceleration (AC) heart rate, rate variability (HRV) assessment tools....