Junjie Chen

ORCID: 0000-0001-6947-3453
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Acute Lymphoblastic Leukemia research
  • Childhood Cancer Survivors' Quality of Life
  • Acute Myeloid Leukemia Research
  • Inflammatory Biomarkers in Disease Prognosis
  • Nasal Surgery and Airway Studies
  • Total Knee Arthroplasty Outcomes
  • Cancer Immunotherapy and Biomarkers
  • Urological Disorders and Treatments
  • Urologic and reproductive health conditions
  • Cardiac Imaging and Diagnostics
  • Lung Cancer Treatments and Mutations
  • Cancer, Lipids, and Metabolism
  • Urinary and Genital Oncology Studies
  • Orthopaedic implants and arthroplasty
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Reconstructive Facial Surgery Techniques
  • Radiomics and Machine Learning in Medical Imaging
  • Lymphoma Diagnosis and Treatment
  • Thermal Regulation in Medicine
  • Full-Duplex Wireless Communications
  • Cardiovascular Function and Risk Factors
  • Cervical and Thoracic Myelopathy
  • Salivary Gland Disorders and Functions
  • Neutropenia and Cancer Infections
  • Temporomandibular Joint Disorders

Southern Medical University
2021-2025

Nanfang Hospital
2021-2025

Zhejiang Chinese Medical University
2014-2025

Eastern Hepatobiliary Surgery Hospital
2022-2024

Second Military Medical University
2022-2024

First Hospital of Jiaxing
2024

First Affiliated Hospital of Wenzhou Medical University
2023

Guangzhou Medical University
2021-2023

Wenzhou Medical University
2023

Central South University
2023

Background: Microvascular invasion (MVI) is closely correlated with poor clinical outcomes in patients hepatocellular carcinoma (HCC). A grading system of MVI needed to assist the management HCC patient. Methods: Multicenter data who underwent liver resection curative intent was analyzed. This established by detected number and distance from tumor boundary MVI. Survival were compared among each group. verified time-receiver operating characteristic curve, time-area under calibration decision...

10.2147/jhc.s447731 article EN cc-by-nc Journal of Hepatocellular Carcinoma 2024-01-01

Human hypertrophic cardiomyopathy, characterized by cardiac hypertrophy and myocyte disarray, is the most common cause of sudden death in young. Hypertrophic cardiomyopathy often caused mutations sarcomeric genes. We sought to determine arrhythmia propensity underlying mechanisms contributing a transgenic (TG) rabbit model (beta-myosin heavy chain-Q403) human cardiomyopathy. Langendorff-perfused hearts from TG (n=6) wild-type (WT) rabbits were optically mapped. The upper lower limits...

10.1161/circresaha.107.161240 article EN Circulation Research 2007-09-21

To evaluate the correlation between obstructive sleep apnea (OSA) and temporomandibular joint (TMJ) morphology, tooth wear condition, orofacial pain through a follow-up program.Seventy one OSA patients were divided into three groups according to their (apnea hypopnea index) AHI: mild group (n = 23), moderate 24), severe 24). All had therapies around six months after confirm diagnosis of OSA. The score condition all recorded via clinical examination. Cone beam computed tomography (CBCT)...

10.1186/s12903-023-03264-9 article EN cc-by BMC Oral Health 2023-08-19

The prognostic value of albumin changes between diagnosis and end-of-treatment (EoT) in diffuse large B-cell lymphoma (DLBCL) remains unknown. We retrospectively analyzed 574 de novo DLBCL patients treated with R-CHOP from our two other centers. All were divided into a training cohort (n = 278) validation 296) depending on the source patients. Overall survival (OS) progression-free (PFS) by method Kaplan–Meier Cox proportional hazard regression model. In cohort, 163 (58.6%) had low serum at...

10.3389/fonc.2020.610681 article EN cc-by Frontiers in Oncology 2021-01-27

Liver metastasis is a common complication in gallbladder cancer (GBC). We design this study to develop models for predicting the development of liver GBC patients and evaluate risk mortality these with metastasis. from Surveillance Epidemiology End Results (SEER) between 2010 2016 were included study. Logistic regression was performed discover factors construct predictive patients. Cox utilized find The area under receiver operating characteristic curve (AUC) calculated performance...

10.3389/fsurg.2022.899896 article EN cc-by Frontiers in Surgery 2022-08-23

To translate and test the psychometric properties of a Chinese version scale to measure Fear Activity in patients with Coronary Artery Disease.A cross-sectional design.The translation Patients Disease included three steps, forward-back translation, expert discussion pilot survey. The internal consistency test-retest reliability were used assess Activity. Content, construct, criterion, known-group validity also evaluated.A total 275 recruited from university-affiliated hospital Guangzhou,...

10.1002/nop2.1663 article EN cc-by-nc-nd Nursing Open 2023-02-25

Myocardial ischemia reperfusion injury (IRI) in acute coronary syndromes is a condition which ischemic/hypoxic to cells subtended by the occluded vessel continues despite successful resolution of thrombotic obstruction. For decades, most efforts attenuate IRI have focused on interdicting singular molecular targets or pathways, but none successfully transitioned clinical use. In this work, we investigate nanoparticle-based therapeutic strategy for profound local thrombin inhibition that may...

10.3390/ijms24087333 article EN International Journal of Molecular Sciences 2023-04-15

Abstract The role of allogeneic hematopoietic stem cell transplantation (allo-HSCT) for adult high-risk acute lymphoblastic leukemia (HR-ALL) remained elusive in the pediatric-inspired regimen era. We conducted a cohort study on outcome allo-HSCT post-consolidation versus chemotherapy HR-ALL first complete remission PDT-ALL-2016 cohort. A total 245 patients with were enrolled, according to donor availability and patients’ preferences, among which 159 received after consolidation therapy, 86...

10.21203/rs.3.rs-4008818/v1 preprint EN cc-by Research Square (Research Square) 2024-03-07

Abstract Colorectal cancer (CRC) represents a considerable global health challenge, ranking third in incidence and second mortality worldwide. However, existing therapies for diseases with advanced stages often fail, thereby necessitating the search more comprehensive treatments. Oncolytic virus, novel anticancer approach, exhibits promising capabilities selectively targeting destroying tumor cells while augmenting their efficacy through genetic engineering modifications. Anticipated as new...

10.1097/ot9.0000000000000051 article EN cc-by-nc-nd Oncology and Translational Medicine 2024-07-02

To investigate the value of pretreatment blood biomarkers combined with magnetic resonance imaging (MRI) in predicting efficacy neoadjuvant chemoradiotherapy (NCRT) patients locally advanced rectal cancer (LARC).This study involved LARC who received NCRT and subsequently underwent total mesenteric excision from June 2015 to 2021 at First Affiliated Hospital Soochow University. Patients incomplete courses therapy, comorbidities other malignancies or diseases that affect outcome, those...

10.3389/fonc.2022.916840 article EN cc-by Frontiers in Oncology 2022-08-09

The nose is the most important part in aesthetic appearance of face because its central position. It difficult to reconstruct a large through-and through defect nasal tip among deformities unique individual characteristics. In this article, we describe successful use modified auricular composite graft (larger than traditional size) for reconstruction transmural defects tip.We retrospectively examined 4 patients diagnosed with between 2009 and 2011; our patients, size was 2 × 1 cm 2.5 cm. All...

10.1097/scs.0000000000001106 article EN Journal of Craniofacial Surgery 2015-01-31

Objective: This retrospective study aimed to compare the efficacy of evacuation assisted by endoscopy and CT-guided minimally invasive aspiration for supratentorial intracerebral hematoma (SICH).Methods: Total 81 patients were classified into two groups receive or aspiration. The therapeutic outcomes compared between groups.Results: rate was significantly higher while infection lower in group than (p < .05). Mortality showed no significant difference groups. operated within six hours had...

10.1080/02688697.2018.1559273 article EN British Journal of Neurosurgery 2019-01-29

Summary The dysregulation of the Janus family tyrosine kinase‐signal transducer and activator transcription (JAK‐STAT) is closely related to acute lymphoblastic leukaemia (ALL), whereas clinical value phosphorylated STAT5 (pSTAT5) remains elusive. Herein we performed a prospective study on significance flow cytometry‐based pSTAT5 in adult B‐ALL patients. A total 184 patients were enrolled Precision‐Classification‐Directed‐Target‐Total‐Therapy (PDT)‐ALL‐2016 cohort between January 2018...

10.1111/bjh.19467 article EN British Journal of Haematology 2024-04-19

Abstract Flowable fill has been widely used as a type of materials in engineering practice. However, the adoption fine-grained soils, especially clay flowable fills faces difficulties such lack mixing efficiency and poor performance. In this study, was prepared using waste excavated soil generated from construction project. Two types silty silt mixed with sand, were used. laboratory tests, slump unconfined compressive oedometer compression drying shrinkage tests conducted. Within tested...

10.1088/1742-6596/2920/1/012025 article EN Journal of Physics Conference Series 2024-12-01
Coming Soon ...