A5035063993- Microfluidic and Bio-sensing Technologies
- Microfluidic and Capillary Electrophoresis Applications
- Spine and Intervertebral Disc Pathology
- 3D Printing in Biomedical Research
- Electrowetting and Microfluidic Technologies
- Innovative Microfluidic and Catalytic Techniques Innovation
- Wound Healing and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Biosensors and Analytical Detection
- Medical Imaging and Analysis
- Cell Image Analysis Techniques
- Electrohydrodynamics and Fluid Dynamics
- Mesenchymal stem cell research
- Circular RNAs in diseases
- Inflammatory mediators and NSAID effects
- Diabetic Foot Ulcer Assessment and Management
- Tissue Engineering and Regenerative Medicine
- Single-cell and spatial transcriptomics
- Plant and Biological Electrophysiology Studies
- Analytical Chemistry and Sensors
- Spinal Fractures and Fixation Techniques
- Surgical Sutures and Adhesives
- Glioma Diagnosis and Treatment
- Musculoskeletal pain and rehabilitation
- Mechanical and Optical Resonators
National University of Singapore
2023-2025
Second Affiliated Hospital of Nanchang University
2021-2024
Nanchang University
2021-2024
Peking University People's Hospital
2024
Chengdu University of Traditional Chinese Medicine
2024
Jishan County People's Hospital
2024
Liaoning Cancer Hospital & Institute
2024
China Medical University
2024
Peking University
2024
Affiliated Eye Hospital of Wenzhou Medical College
2024
Cellulose/chitosan composite, as a mature commercial antibacterial dressing, is an important type of wound repair material. However, how to achieve the perfect compound two components and improve activity major, lingering issue. In this study, bifunctional group modified bacterial cellulose (DCBC) was prepared by carboxymethylation selective oxidation. Further, chitosan (CS) compounded in network DCBC self-crosslinking form dialdehyde carboxymethyl cellulose/chitosan composites (S-DCBC/CS)....
Microfluidics has become recognized as a powerful platform technology with wide range of applications in various fields, such biology, biomedicine, chemistry and environment. To achieve higher performance, microfluidic devices are required to have superior optical transparency; mechanical, chemical thermal stability; well easy design fabrication. All these requirements make glass an attractive ideal material for the fabrication due its excellent characteristics optical, thermal, electrical...
Abstract Single-cell encapsulation in droplet microfluidics is commonly hindered by the tradeoff between cell suspension density and on-chip focusing performance. In this study, we introduce a novel microfluidic chip to overcome challenge. The comprises double spiral unit, flow resistance-based sample enrichment module with fine-tunable outlets, crossflow generation unit. Utilizing low-density cell/bead (2 × 10 6 objects/mL), cells/beads are focused into near-equidistant linear arrangement...
Cell rotation is one of the most important techniques for cell manipulation in modern bioscience, as it not only permits observation from any arbitrary angle, but also simplifies procedures analyzing mechanical properties cells, characterizing physiology, and performing microsurgery. Numerous approaches have been reported rotating cells a wide range academic industrial applications. Among them, popular are micro-robot-based direct contact field-based non-contact methods (e.g., optical,...
A viscoelastic microfluidic device for shape-based separation of drug-treated Escherichia coli .
Objective: To accelerate wound healing through promoting vascularization by using reactive oxygen species (ROS)-responsive nanoparticles loaded with stromal cell-derived factor-1α (SDF-1α). Methods: The ROS-reactive nanomaterial poly-(1,4-phenyleneacetone dimethylene thioketal) was synthesized, and its physical chemical properties were characterized. ROS-responsive containing SDF-1α prepared a multiple emulsion solvent evaporation method. loading capacity, stability, activity of the...
The benefits of impedance cytometry include high-throughput and label-free detection, while long-term calibration is required to remove the effects detection circuits. This study presents a novel system, called parallel cytometry, simplify analysis signals. Furthermore, target objects can be detected even when benchmarked against similar objects. Parallel dual microchannels allow simultaneous reference particles in two separate microchannels, without premixing suspensions. pulses both appear...
Imaging flow cytometry is a powerful tool by virtue of its capability for high-throughput cell analysis. The advent high-speed optical imaging methods on microfluidic platform has significantly improved throughput and brought many degrees freedom to instrumentation applications over the last decade, but it also poses predicament chips. Specifically, as increases, speed increases (currently reaching 10 m/s): consequently, increased hydrodynamic pressure chip deforms wall microchannel produces...
We optimized the microfluidic chip of imaging flow cytometry by setting horizontal connections; By OTS microscopy, cells can be imaged at 40 m s −1 in our device.
Intracellular components (including organelles and biomolecules) at the submicron level are typically analyzed in situ by special preparation or expensive setups. Here, a label-free cost-effective approach of screening microalgal single-cells subcellular resolution is available based on impedance cytometry. To best our knowledge, it first time that relationships between signals intracellular biomolecules shown. Experiments were performed Euglena gracilis (E. gracilis) cells incubated under...
Abstract The electrical penetration of the cell membrane is vital for determining interior via impedance cytometry. Herein, we propose a method conductivity through tilting levels pulses. When occurs, high-frequency current freely passes membrane; thus, intracellular distribution can directly act on Numerical simulation shows that an uneven component affect pulses, and start increasing when electrically penetrated. Experimental evidence higher detection frequencies (>7 MHz) lead to wider...
BACKGROUND Pyogenic spondylodiscitis is infection of the intervertebral disc or discs and adjacent vertebrae. This retrospective study aimed to compare effectiveness percutaneous endoscopic lumbar debridement (PELD) versus posterior interbody fusion (PLIF) in 40 patients with pyogenic (PSD). MATERIAL AND METHODS Medical records who underwent PELD (n=18) PLIF (n=22) for PSD between 2018 2023 were reviewed. The recorded outcomes encompassed surgical duration, intraoperative blood loss,...
Current wound scaffold dressing constructs can facilitate healing but do not exhibit antibacterial activity, resulting in high infection rates. We aimed to endow with anti-infective ability by polyhexamethylenebiguanide (PHMB). prepared PHMB hydrogel at varying concentrations (0.25%, 0.5%, 1%, 2%) and assessed release cytotoxicity. was added the generate a hydrogel-modified dressing. Wound prevention were evaluated using full-thickness skin defect model rats. In vitro, time positively...
Stump problems (SPs) secondary to traumatic lower limb amputation had a crucial influence on amputees' ability return living and work. The purpose of this study was investigate the surgical management strategies SPs after above-ankle trauma. A cohort clinical cases, who were troubled by following trauma, undergone revision surgery stump analyzed retrospectively. Various factors noted like sex, unilateral or bilateral, type, causes Different excess soft tissue (where considerable amount...