Yue Cao

ORCID: 0000-0003-0487-412X
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Nanoplatforms for cancer theranostics
  • Advanced Nanomaterials in Catalysis
  • Nanoparticle-Based Drug Delivery
  • Advancements in Battery Materials
  • Photoacoustic and Ultrasonic Imaging
  • Advanced Battery Materials and Technologies
  • Photodynamic Therapy Research Studies
  • Glioma Diagnosis and Treatment
  • Bone Tissue Engineering Materials
  • Advanced Sensor and Energy Harvesting Materials
  • 3D Printing in Biomedical Research
  • Polymer composites and self-healing
  • Advanced Battery Technologies Research
  • Tissue Engineering and Regenerative Medicine
  • Adenosine and Purinergic Signaling
  • Quantum Information and Cryptography
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Algebraic structures and combinatorial models
  • biodegradable polymer synthesis and properties
  • Advanced Database Systems and Queries
  • Advanced Drug Delivery Systems
  • Quantum many-body systems
  • Luminescence and Fluorescent Materials
  • Conducting polymers and applications
  • Porphyrin and Phthalocyanine Chemistry

Huawei Technologies (United States)
2025

Jilin University
2022-2024

First Hospital of Jilin University
2022-2024

China Communications Construction Company (China)
2024

Argonne National Laboratory
2022

University of Chicago
2022

Tsinghua University
2016-2021

Jilin Engineering Normal University
2020-2021

University of California, Riverside
2016-2021

Chinese Academy of Sciences
2010-2020

Self-healing materials can repair damage caused by mechanical wear, thereby extending lifetime of devices. A transparent, self-healing, highly stretchable ionic conductor is presented that autonomously heals after experiencing severe damage. The design this self-healing polymer uses ion-dipole interactions as the dynamic motif. unique properties material when used to electrically activate transparent artificial muscles are demonstrated.

10.1002/adma.201605099 article EN Advanced Materials 2016-12-23

Abstract Polymer materials that are able to self‐heal in humid conditions or even water highly desirable for their industrial applications. However, the development of underwater self‐healing polymer is very challenging since molecules can readily disturb traditional noncovalent bonds, such as saturate hydrogen coordinate with metal cation, well solvate ions. Here, a new type dipole–dipole interactions employed driving force, combining polar and hydrophobic fluorinated polymers, successfully...

10.1002/adma.201804602 article EN Advanced Materials 2018-10-09

The specific diagnosis and treatment of gliomas is a primary challenge in clinic due to their high invasiveness blood-brain barrier (BBB) obstruction. It highly desirable find multifunctional agent with good BBB penetration for precise theranostics. Herein, we design construct core-shell structured nanotheranostic (YVO4:Nd3+-HMME@MnO2-LF, marked as YHM) YVO4:Nd3+ particles the core MnO2 nanosheets shell. Sonosensitizer hematoporphyrinmonomethyl ether (HMME) lactoferrin (LF) were further...

10.1038/s41377-022-00794-9 article EN cc-by Light Science & Applications 2022-04-29

The metabolic reprogramming of glioblastoma (GBM) poses a tremendous obstacle to effective immunotherapy due its impact on the immunosuppressive microenvironment. In this work, hydrogen-bonded organic framework (HOF) specifically designed for GBM is developed, taking advantage relatively isolated cholesterol metabolism microenvironment in central nervous system (CNS). HOF-based biotuner regulates extra/intracellular metabolism, effectively blocking programmed cell death protein 1/programmed...

10.1002/adma.202303567 article EN Advanced Materials 2023-07-19

Abstract The growth of lithium dendrites and low coulombic efficiency restrict the development Li metal anodes. Polymer electrolytes are expected to be promising candidates solve issue, but ways obtain a polymer electrolyte that integrates high ionic conductivity mechanical toughness is still challenging. By introducing double network into design reshape it, tough was developed with conductivity, stable operation anodes further realized. (DNW) gel has modulus 44.3 MPa fracture energy 69.5 kJ...

10.1002/anie.201709774 article EN Angewandte Chemie International Edition 2017-12-16

Uncontrollable growth of Li dendrites is a big problem for metal batteries. In this work, we described new universal strategy in situ formation interfacial coating with methyl viologen to achieve stable cycling lithium anode. After treating the layer 0.5 wt % ether electrolyte, highly uniform, stable, and ionically conductive can be formed on surface because electrochemical reduction. The generate better control ion flow suppress dendrite therefore form uniform solid electrolyte interphase....

10.1021/acs.chemmater.6b05475 article EN Chemistry of Materials 2017-04-10

Oral insulin delivery has revolutionized diabetes treatment, but challenges including degradation in the gastrointestinal environment and low permeation across intestinal epithelium remain. Herein, to overcome these barriers, we developed a novel biodegradable nanocomposite microsphere embedded with metal–organic framework (MOF) nanoparticles. An iron-based MOF nanoparticle (NP) (MIL-100) was first synthesized as carrier an loading capacity of 35%. The insulin-loaded MIL-100 nanoparticles...

10.1021/acsami.0c04303 article EN ACS Applied Materials & Interfaces 2020-04-28

Abstract Ferroptosis, characterized by iron accumulation and lipid peroxidation (LPO), can avoid the intrinsic apoptotic resistance of tumor cells have been explored for glioblastoma (GBM) therapy. However, direct delivery species may trigger severe adverse side effects. Using nonferrous to induce LPO‐mediated ferroptosis maybe a promising strategy GBM treatment, but there is still no report till now. Therefore, in this study, first an intelligent blood–brain barrier (BBB)‐permeable...

10.1002/adfm.202209227 article EN Advanced Functional Materials 2022-11-28

Abstract Gliomas are common and refractory primary tumors closely associated with the fine structures of brain. Photothermal therapy (PTT) has recently shown promise as an effective treatment for gliomas. However, nonspecific accumulation photothermal agents may affect adjacent normal brain structures, inflammatory response induced during PTT result in increased risk tumor recurrence or metastasis. Here, design fabrication intelligent nanomachine is reported based on Gd 2 O 3 @Ir/TMB‐RVG29...

10.1002/advs.202204937 article EN cc-by Advanced Science 2022-11-27

Neuroinflammation has been known as an important pathogenetic contributor of Alzheimer's disease (AD). Pterostilbene is a natural compound which neuroprotective activity. However, the effect pterostilbene on amyloid-β (Aβ)-induced neuroinflammation not clarified. The aim present study was to investigate Aβ-induced in microglia. results indicated that attenuated Aβ1-42 -induced cytotoxicity BV-2 cells. induced NO production and iNOS mRNA protein expression, while inhibited induction....

10.1002/jcb.27023 article EN Journal of Cellular Biochemistry 2018-05-08

Timestamps are often found to be dirty in various scenarios, e.g., distributed systems with clock synchronization problems or unreliable RFID readers. Without cleaning the imprecise timestamps, temporal-related applications such as provenance analysis pattern queries not reliable. To evaluate correctness of temporal constraints could employed, which declare distance restrictions between timestamps. Guided by on this paper, we study a novel problem repairing inconsistent timestamps that do...

10.14778/2977797.2977798 article EN Proceedings of the VLDB Endowment 2016-06-01

Parkinson's Disease is characterized by the loss of dopaminergic neurons in substantia nigra pars compacta, extracellular accumulation toxic α-synuclein (αSYN) aggregates, and neuroinflammation. Microglia, resident macrophages brain, are one critical cell types involved Upon sensing stimuli or experiencing oxidative stress, microglia become activated, which further exacerbates In addition, as first line defense central nervous system, play a role αSYN clearance degradation. While...

10.3389/fbioe.2020.00112 article EN cc-by Frontiers in Bioengineering and Biotechnology 2020-02-21

Accurate diagnosis and highly effective treatment of glioblastoma are still challenges in clinic. Near-infrared (NIR) light triggered fluorescence imaging photodynamic therapy (PDT) showed the potential for theranostics glioblastoma, but presence blood-brain barrier (BBB) hypoxia limited effect. Herein, novel theranostic nanoagents with YOF:Nd3+ as core, MnO2 shell, further loading photosensitizer (indocyanine green, ICG) glucose oxidase (GOx) were successfully constructed, modified...

10.1021/acsami.2c05354 article EN ACS Applied Materials & Interfaces 2022-07-01

Abstract: Miniaturized pixel sizes in near-eye digital displays lead to emission patterns with large divergence angles, necessitating efficient beam collimation solutions improve the light coupling efficiency. Traditional optics, such as lenses and cavities, are wavelength-sensitive cannot simultaneously collimate red (R), green (G), blue (B) light. In this work, we employed inverse design optimization finite-difference time-domain (FDTD) simulation techniques a collimator comprised of...

10.3390/nano15030190 article EN cc-by Nanomaterials 2025-01-25

This article reports tunable crosslinking, reversible phase transition, and three-dimensional printing (3DP) of hyaluronic acid (HyA) hydrogels via dynamic coordination Fe3+ ions with their innate carboxyl groups for the first time. The concentrations H+ reaction time determine ratios mono-, bi-, tridentate coordination, leading to low-to-high crosslinking densities solid-liquid transition HyA hydrogels. At monodentate-dominant liquid have low (HyA_L). mixed bonding, solid medium (HyA_M)....

10.1021/acsabm.0c01300 article EN ACS Applied Bio Materials 2021-02-15

Glioblastoma (GBM) is a common malignant tumor in brain, and the treatment still challenge owing to high invasiveness existence of blood-brain barrier (BBB). Although temozolomide (TMZ) first line medication, its efficacy not ideal, which related defect dose distribution drug resistance. It urgent develop novel BBB-permeable nanoagent with multiple therapeutic modalities for improving effect GBM. In this work, we constructed an intelligent nanoplatform (CTHG-Lf NPs) hollow mesoporous copper...

10.1016/j.ejps.2022.106319 article EN cc-by-nc-nd European Journal of Pharmaceutical Sciences 2022-11-01

The capacity to specifically destroy cancer cells while avoiding normal tissue is urgently desirable in treatment. Herein, a photothermal-trigger-released system serves as photoacoustic imaging agent constructed by entrapping diketopyrrolopyrrole-based conjugated polymers and curcumin poly(ethylene glycol) (PEG)-protected thermoresponsive liposomal phospholipid bilayer. This lipid nanostructure can improve the bioavailability of hydrophobic agents for photothermal treatment with high...

10.1021/acs.biomac.7b00464 article EN Biomacromolecules 2017-06-27

In this paper, we prepared doxorubicin-loaded folic acid-functionalized pH-sensitive photothermal therapy (PTT) traceable hollow mesoporous silica nanoparticles (DOX-HPCF) as a drug carrier for liver cancer treatment. According to TEM characterization, (HMSN) are monodispersed spherical particles with structure. vitro release experiments showed that HPCF exhibited release. Cell uptake was successfully absorbed by SMMC-7721 cells. addition, DOX-HPCF significantly inhibited the proliferation...

10.1080/10717544.2020.1718801 article EN cc-by Drug Delivery 2020-01-01

Abstract The electrochemical conversion reaction, usually featured by multiple redox processes and high specific capacity, holds great promise in developing high‐energy rechargeable battery technologies. However, the complete structural change accompanied spontaneous atomic migration volume variation during charge/discharge cycle leads to electrode disintegration performance degradation, therefore severely restricting application of conventional conversion‐type electrodes. Herein,...

10.1002/smll.202204912 article EN publisher-specific-oa Small 2022-10-20

A novel nanosystem based on NH 2 -MIL-53 (Fe) modified up-conversion nanoparticles is reported for combined NIR light-mediated photodynamic therapy, chemodynamic therapy and chemotherapy of orthotopic gliomas.

10.1039/d2tb02273g article EN Journal of Materials Chemistry B 2022-12-12

Invasive tumors are difficult to be completely resected in clinical surgery due the lack of clear resection margins, which greatly increases risk postoperative recurrence. However, chemotherapy and radiotherapy as traditional means adjuvant therapy, limited applications, such multi-drug resistance low sensitivity, etc. Therefore, an engineered magnesium alloy rod is designed a implant remove residual tumor tissue inhibit recurrence by gas mild magnetic hyperthermia therapy (MMHT). As...

10.1016/j.bioactmat.2024.06.004 article EN Bioactive Materials 2024-06-26
Coming Soon ...