- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Liver Diseases and Immunity
- Organ Transplantation Techniques and Outcomes
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Cardiovascular Disease and Adiposity
- Securities Regulation and Market Practices
- Pharmaceutical industry and healthcare
- Corporate Identity and Reputation
- Hepatitis Viruses Studies and Epidemiology
- Thermoregulation and physiological responses
- T-cell and B-cell Immunology
- Viral gastroenteritis research and epidemiology
- Obstructive Sleep Apnea Research
- Mast cells and histamine
- Gallbladder and Bile Duct Disorders
- Immune Cell Function and Interaction
- Systemic Lupus Erythematosus Research
- Climate Change and Health Impacts
- Bariatric Surgery and Outcomes
- Drug-Induced Adverse Reactions
- Diagnosis and Treatment of Venous Diseases
- Probiotics and Fermented Foods
- Food Safety and Hygiene
University Hospital of Bern
2018-2024
Azienda Socio Sanitaria Territoriale Santi Paolo e Carlo
2021
Ospedale San Paolo
2021
University of Bern
2018-2019
Klinikum im Friedrichshain
2019
Universitat Autònoma de Barcelona
2018
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2018
Vall d'Hebron Hospital Universitari
2018
University of Milan
2018
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2013-2014
•Total cross-sectional SPSS area (TSA) predicts survival in patients with advanced chronic liver disease.•The cut-off for TSA that is associated worse corresponds to a single shunt of >10 mm diameter.•This study may impact on the clinical use TSA/SPSS risk stratification and decision-making management cirrhosis. Background & AimsSpontaneous portosystemic shunts (SPSS) frequently develop Recent data suggested presence large complications, especially overt hepatic encephalopathy (oHE)....
Baveno-VI guidelines recommend that patients with compensated cirrhosis liver stiffness by transient elastography (LSM-TE) <20 kPa and platelets >150,000/mm(3) do not need an esophagogastroduodenoscopy (EGD) to screen for varices, since the risk of having varices needing treatment (VNT) is <5%. It remains uncertain if this tool can be used in cholestatic diseases (ChLDs): primary biliary cholangitis (PBC) sclerosing (PSC). These may have a pre-sinusoidal component portal hypertension could...
Background/aim: Recurrent primary biliary cholangitis (rPBC) develops in approximately 30% of patients and negatively impacts graft overall patient survival after liver transplantation (LT).There is a lack data regarding the response rate to ursodeoxycholic acid (UDCA) rPBC.We evaluated large, international, multi-center cohort assess performance scores for PBC predict risk LT with rPBC.Methods: A total 332 rPBC were from 28 centres across Europe, North South America.The median age at time...
Natural killer cells are involved in the complex mechanisms underlying autoimmune diseases but few studies have investigated their role hepatitis. Killer immunoglobulin-like receptors key regulators of natural cell-mediated immune responses.KIR gene frequencies, KIR haplotypes, ligands and combinations KIRs HLA Class I were 114 patients diagnosed with type 1 hepatitis compared a group 221 healthy controls. II antigen frequencies to those 551 unrelated families representative Sardinian...
Abstract Background & Aims Controlled attenuation parameter (CAP) for steatosis assessment has not been validated in compensated advanced chronic liver disease (cACLD). We primarily aimed at assessing the accuracy of CAP diagnosis and quantification cACLD. Secondary aim: to assess validity non‐invasive criteria cACLD according stiffness measurement (LSM). Methods This is a single‐centre retrospective study including patients with defined as LSM ≥10 kPa, biopsy (reference standard...
Obesity and steatosis have been associated with liver disease progression in patients compensated advanced chronic (cACLD) (liver stiffness measurement [LSM] ≥ 10 kPa). The controlled attenuation parameter (CAP) estimates during LSM by transient elastography. We aimed to evaluate whether CAP is the development of clinically relevant events cACLD. Consecutive cACLD measurements observed between September 2013 2015 were retrospectively studied. Classical decompensation severe bacterial...
Understanding patients' attitudes to clinical experiences is essential for developing high-quality patient-centred healthcare, as a better knowledge of tolerance and satisfaction might allow implementing measures that ameliorate comfort, care use resources. We aimed describe invasive hepatic haemodynamic procedures, investigate which factors influence perspective in this field. Visual Analogue Scale (VAS) questionnaires regarding pain duration (for tolerance), comfort general handling...
General (GA)- and epidural-anesthesia may cause a drop in body-core-temperature (BCTdrop), hypothermia, which alter tissue oxygenation (StO2) microperfusion after cytoreductive surgery for ovarian cancer. Cell metabolism of subcutaneous fat- or skeletal muscle cells, measured microdialysis, be affected. We hypothesized that forced-air prewarming during epidural catheter placement induction GA maintains normothermia improves microperfusion.After ethics approval 47 women scheduled were...
Ailments such as diarrhoea and antibiotic-associated gut symptoms are generally self-managed using probiotics. Real-world data on reasons behind self-medication with over-the-counter (OTC) products patient-reported outcomes can be investigated strategically by the pharmacists. This study evaluates use of Bacillus clausii (Enterogermina®) at Italian community pharmacies among self-medicating patients, their treatment habits perceived benefits. is a multicentre, prospective, non-interventional...
Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a potentially life-threatening drug reaction, which can affect multiple organs. Patients DRESS hepatic manifestations may present alterations ranging from mild hepatitis to acute liver failure. The diagnosis might be difficult, the management of these patients challenging. This report analyzes series five cases reporting clinical presentation, ranged failure, discussed their treatment.