A5033777994- COVID-19 Clinical Research Studies
- Clinical Laboratory Practices and Quality Control
- Hemoglobinopathies and Related Disorders
- Venous Thromboembolism Diagnosis and Management
- Sepsis Diagnosis and Treatment
- Iron Metabolism and Disorders
- Chronic Lymphocytic Leukemia Research
- Blood properties and coagulation
- Lymphoma Diagnosis and Treatment
- Lipid metabolism and disorders
- Blood Coagulation and Thrombosis Mechanisms
- Body Composition Measurement Techniques
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- SARS-CoV-2 and COVID-19 Research
- Pregnancy and Medication Impact
- Heart Failure Treatment and Management
- Lipoproteins and Cardiovascular Health
- Long-Term Effects of COVID-19
- Erythrocyte Function and Pathophysiology
- Blood groups and transfusion
- Erythropoietin and Anemia Treatment
- Pleural and Pulmonary Diseases
- Platelet Disorders and Treatments
- Acute Myocardial Infarction Research
Hospital Universitari Germans Trias i Pujol
2015-2025
Universitat Autònoma de Barcelona
2010-2024
Spanish Society of Family and Community Medicine
2023
Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol
2021
University of Coimbra
2019
Institut Català de la Salut
2019
Early sepsis diagnosis has emerged as one of the main challenges in emergency room. Measurement biomarkers is largely used current practice to improve accuracy. Monocyte distribution width (MDW) a recent new biomarker, available part complete blood count with differential. The objective was evaluate performance MDW for detection department (ED) and compare procalcitonin (PCT) C-reactive protein (CRP).
Abstract Background Myocardial injury is a common finding in COVID‐19 strongly associated with severity. We analysed the prevalence and prognostic utility of myocardial injury, characterized by elevated cardiac troponin, large population patients, further evaluated separately role troponin T I. Methods This multicentre, retrospective observational study enrolling patients laboratory‐confirmed who were hospitalized 32 Spanish hospitals. Elevated levels defined as values above sex‐specific...
Summary Low serum erythropoietin ( EPO ) is a minor criterion of Polycythaemia Vera PV but its diagnostic usefulness relies on studies performed before the discovery JAK 2 V617F mutation. The objective present study was to evaluate accuracy and allele burden as markers well combination different criteria in 287 patients (99 with , 137 Essential Thrombocythaemia 51 non‐clonal erythrocytosis). showed good marker for area under curve AUC chemiluminescent‐enhanced enzyme immunoassay CEIA being...
Identification of predictors for severe disease progression is key risk stratification in COVID-19 patients. We aimed to describe the main characteristics and identify early outcomes among hospitalized patients with Spain. This was an observational, retrospective cohort study (BIOCOVID-Spain study) including admitted 32 Spanish hospitals. Demographics, comorbidities laboratory tests were collected. Outcome in-hospital mortality. For analysis, values previously adjusted assure comparability...
Abstract Introduction UniCel DxH900 (Beckman Coulter, Miami, Florida, USA) is a quantitative, multi‐parameter, automated hematology analyzer for in vitro diagnostic use clinical laboratories. The aim of this study was to evaluate the analytical performance new verify its and utility laboratory tertiary care hospital Spain. most important novel feature offered by providing MDW (monocyte distribution width), hematologic parameter which being clinically validated as an early sepsis indicator...
Interferences in the clinical laboratory may lead physicians misinterpret results for some biological analytes. The most common analytical interferences include hemolysis, icterus and lipemia. Lipemia is defined as turbidity a sample caused by accumulation of lipoproteins, mainly very-low density lipoproteins (VLDL) chylomicrons. Several methods are available detection lipemic samples, including index, or triglyceride quantification serum plasma mean corpuscular hemoglobin (MCHC)...
The purpose of this work is to develop a hematocrit-independent method for the detection beta-thalassemia trait (β-TT) and iron deficiency anemia (IDA), through rheological characterization whole blood samples from different donors. results obtained herein are basis development front microrheometry point-of-care device diagnosis clinical follow-up β-TT patients suffering hematological diseases alterations in morphology red cell (RBC). viscosity calculated as function mean velocity by...
Abstract Background Differences between follicular lymphoma (FL) and diffuse large B-cell lymphoma/high-grade (DLBCL/HGBL) by flow cytometry are underexplored. Methods We retrospectively assessed results from 191 consecutive lymph node biopsies diagnosed with FL or DLBCL/HGBL. Results The only parameters that differed the 2 groups in derivation cohort were forward scatter side (P < 10–6; area under curve [AUC], 0.75–0.8) %CD23 = .004; receiver characteristic operating curve, 0.64)....
Pre-analytical and analytical errors can threaten the reliability of flow cytometry (FC) results. A potential solution to some these is use dry, pre-mixed antibodies, such as ClearLLab 10C system. The purpose present study was compare diagnostic performance B cell tube with that our standard laboratory practice.We compared diagnoses made (experimental strategy) those practice (standard strategy). Samples were selected aiming for representation full spectrum disorders, an emphasis on mature...