A5072982384- Emergency and Acute Care Studies
- Trauma and Emergency Care Studies
- Heart Failure Treatment and Management
- Chronic Disease Management Strategies
- Inflammation biomarkers and pathways
- Aortic Disease and Treatment Approaches
- Cardiac Arrest and Resuscitation
- Cardiac Ischemia and Reperfusion
- Trace Elements in Health
- Gout, Hyperuricemia, Uric Acid
- Muscle and Compartmental Disorders
- Family and Patient Care in Intensive Care Units
- Dialysis and Renal Disease Management
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Systemic Lupus Erythematosus Research
- Cardiovascular Function and Risk Factors
- COVID-19 Pandemic Impacts
- Renal and related cancers
- Fatty Acid Research and Health
- Inflammasome and immune disorders
- Iron Metabolism and Disorders
- Chronic Kidney Disease and Diabetes
- Viral Infections and Outbreaks Research
- Phytochemicals and Medicinal Plants
- Immune Response and Inflammation
Tianjin Medical University General Hospital
2017-2025
Rutin is a flavanol-type polyphenol that consists of flavanol quercetin and the disaccharide rutinose, which has been reported to exert various biological effects such as antioxidant anti-inflammatory activities. It not clear whether rutin protective effect on sepsis-induced cardiomyopathy (SIC). In this study, we used male C57BL/6 mice cecal ligation puncture (CLP) surgery establish model SIC. was precautionarily treated (50, 100, 200 mg/kg per day, 7 days) before CLP. The results showed...
Objective To evaluate the clinical features, risk factors, and prognostic significance of different Stanford types acute aortic dissection (AAD). Methods We retrospectively analyzed data predictors in 105 patients with AAD (37 type A 68 B) at Tianjin Medical University General Hospital 4th Central from January 2014 to November 2015. Results Patients Marfan syndrome bicuspid valve constituted 24.3% 8.1%, respectively, AAD; these proportions were significantly higher than those B (7.4% 0.0%,...
Aim: Sepsis is an extremely complex, threatening and difficult-to-treat disease, which can occur at any age under underlying disease. RNF20 regulate NF-kappaB (NF-κB) signaling pathway the transcription of inflammatory factors target genes. Therefore, it great significance to study function in clinical treatment sepsis its mechanisms.Methods: C57BL/6 mice were subjected cecal ligation puncture (CLP) surgery. THP-1 cells induced with Lipopolysaccharide for 4 h.Results: gene, mRNA expression...
Sepsis is a fatal systemic inflammatory disease that causes septic acute kidney injury (AKI). In this work, we explored the roles of circ_0040994 in lipopolysaccharide (LPS)-induced human kidney-2 (HK2) cell injury.Circ_0040994, miR-17-5p and transient receptor potential melastatin 7 (TRPM7) expression were detected by qRT-PCR. Cell functions examined MTT assay, flow cytometry western blot, ELISA oxidative stress assay. The molecular association was dual-luciferase reporter...
Do-not-attempt-resuscitation (DNAR) orders are designed to allow patients opt out of receiving cardiopulmonary resuscitation in the event a cardiac arrest. While DNAR has become standard component medical care, there is limited research available specifically focusing on context emergency departments China. This study aimed fill that gap by examining factors related among department general tertiary teaching hospital Retrospective observational study. Emergency department. and analysis adult...
<bold>Objectives:</bold> The aim of this study was to investigate coronavirus disease 2019 (COVID-19) epidemic characteristics in Africa and provide some references prevent pandemic. <bold>Methods:</bold> We collect information the laboratory-confirmed case COVID-19 that has been reported since April 28, 2020 Africa, describe different regions predict spread trend. <bold>Results:</bold> (1) There are 35,309 cases 1,522 deaths 54 African countries. Both amount death toll Northern higher than...
Abstract Background With more emergency visits, there is increasing pressure to provide medical services globally and locally. This study aimed investigate the epidemiological characteristics disease spectrum of patients presenting in last three years Department Emergency Medicine Tianjin Medical University General Hospital, a tertiary hospital Tianjin, China, improve medicine department. Methods A retrospective was conducted on all Hospital from Jan 1, 2017, 00:00:00 Dec 31, 2020, 23:59:59,...
Objective To assess the effect of impedance threshold device (ITD) with cardiopulmonary resuscitation (CPR) in heart arrest patients. Methods Systematic searches were conducted PubMed, ISI WOK, Science Online, Nature, CMCC, Wangfang data, CNKI and VIP to collect clinical comparative study on whether apply ITD from 2000 June 2015. Two reviewers independently screened articles according inclusion exclusion criteria, extracted data evaluated quality included studies. The meta-analysis...
BACKGROUND:Lupus erythematosus (LE) is mainly clinically divided into cutaneous lupus (CLE) and systemic (SLE) depending on the presence of multi-system manifestations. The most common subtype CLE discoid (DLE). Graves’ disease (GD) immunologically characterized by lymphocytic infiltration thyroid gland thyroid-stimulating hormone (TSH) receptor antibodies (TSH-R-Ab), autoimmune pathogenic cause hyperthyroidism. Autoimmune dysfunction has been widely described in association with rheumatic...
Objective To show epidemiological characteristics of adult emergency patients and to provide data support for grading clinics. Methods Adult (older than 14 years) from 50 hospitals in Tianjin were included. Name, gender age patients, as well visiting time/department, chief complaint, severity the disease, prognosis considered cross-sectional survey 8: 00, 30 Aug 2016 31 2016. Chi-squared test, Fisher’s exact or t test was used statistical analysis appropriate. Results Of 6 569...
Abstract Acute kidney injury (AKI) is an important complication of rhabdomyolysis(RM),but there lack effective treatments.Ulinastatin (UTI) a broad-spectrum serine protease inhibitor isolated and purified from human urine with strong anti-inflammatory cytoprotective actions.The aim this research was to investigate the effect potential mechanism UTI on RM-induced AKI(RM-AKI). We established AKI model myoglobin (Mb) stimulated- NRK-52E cells model.In vivo, twenty-four rats were randomly...
Abstract Background: With more emergency visits, there is increasing pressure to provide medical services globally and locally. This study aimed investigate the epidemiological characteristics disease spectrum of patients presenting in last three years Department Emergency Medicine Tianjin Medical University General Hospital, a tertiary hospital Tianjin, China, improve medicine department. Methods: A retrospective was conducted on all Hospital from Jan 1, 2017, 00:00:00 Dec 31, 2020,...
Abstract Background: The purpose of this study was to investigate the effect BOPPPS model (bridge-in, learning objective, pretest, participatory learning, posttest, and summary) with PAL (Peer-assisted learning) medical humanities methods on Chinese Medical Students in Cardiopulmonary Resuscitation Courses. Methods: Participants were long-term students Tianjin University who accepted emergency medicine courses from 2015 2020. Forward-looking descriptive research phased CPR curriculum...