A5100458632- Advanced X-ray and CT Imaging
- 3D Printing in Biomedical Research
- Radiomics and Machine Learning in Medical Imaging
- Advanced Sensor and Energy Harvesting Materials
- Additive Manufacturing and 3D Printing Technologies
- Nanoplatforms for cancer theranostics
- Extracellular vesicles in disease
- Molecular Sensors and Ion Detection
- Bladder and Urothelial Cancer Treatments
- Advanced oxidation water treatment
- Environmental remediation with nanomaterials
- Advanced Materials and Mechanics
- Graphene and Nanomaterials Applications
- Analytical Chemistry and Sensors
- Electrochemical sensors and biosensors
- MRI in cancer diagnosis
- Tactile and Sensory Interactions
- Antenna Design and Optimization
- Electrospun Nanofibers in Biomedical Applications
- Polymer composites and self-healing
- Fuel Cells and Related Materials
- Antenna Design and Analysis
- Membrane Separation Technologies
- Advanced Photocatalysis Techniques
- Ferroptosis and cancer prognosis
First Affiliated Hospital of Dalian Medical University
2024-2025
Harvard University
1998-2025
Dalian Medical University
2024-2025
Brigham and Women's Hospital
1996-2025
General Hospital of Shenyang Military Region
2024-2025
Shanghai Mental Health Center
2025
Shanghai Jiao Tong University
2020-2025
Nanjing Normal University
2024
Jiangsu Key Laboratory of 3D Printing Equipment and Manufacturing
2024
Zhejiang Sci-Tech University
2024
Direct injection of cell-laden hydrogels shows high potentials in tissue regeneration for translational therapy. The traditional are often used as bulk space fillers to defects after injection, likely limiting their structural controllability. On the other hand, patterned hydrogel constructs necessitate invasive surgical procedures. To overcome these problems, herein, we report a unique strategy encapsulating living human cells pore-forming gelatin methacryloyl (GelMA)-based bioink...
In this study, poly(4-vinylpyridine) (P4VP) was first grafted onto the surface of halloysite nanotubes (HNTs) via in situ polymerization, and then, silver ions were immobilized on P4VP complex reaction. Finally, reduced to nanoparticles (Ag NPs). Polyethersulfone (PES) ultrafiltration membranes bending with modified HNTs loaded Ag NPs prepared phase inversion. FT-IR spectra TGA results showed that successfully. The contact angle data indicated hydrophilicity enhanced by addition HNTs....
The increasing demand in rapid wound dressing and healing has promoted the development of intraoperative strategies, such as bioprinting, which allows deposition bioinks directly at injury sites to conform their specific shapes structures. Although successes have been achieved varying degrees, either instrumentation remains complex high-cost or bioink is insufficient for desired cellular activities. Here, we report a cost-effective, open-source handheld bioprinter featuring an ergonomic...
Abstract Poor fiber orientation and mismatched bone–ligament interface fusion have plagued the regeneration of periodontal defects by cell‐based scaffolds. A 3D bioprinted biomimetic module is designed with high architectural integrity using a methacrylate gelatin/decellularized extracellular matrix (GelMA/dECM) cell‐laden bioink. The presents favorable mechanical properties guidance high‐precision topographical cues provides biochemical environment conducive to regulating encapsulated cell...
Abstract Realizing the full potential of self‐healing materials in stretchable electronics necessitates not only low modulus to enable high adaptivity, but also toughness resist crack propagation. However, existing toughening strategies for soft have modestly improves mechanical dissipation near tip ( Г D ), and invariably compromise material's inherent softness autonomous healing capabilities. Here, a synthetic microporous architecture is demonstrated that unprecedently toughens softens...
Due to multidrug resistance and the high risk of recurrence, effective less toxic alternative pancreatic cancer treatments are urgently needed. Pancreatic cells highly resistant apoptosis but sensitive ferroptosis. In this study, an innovative nanoplatform (AsIr@PDA) was developed by electrostatic adsorption a cationic iridium complex (IrFN) onto two-dimensional (2D) arsenene nanosheets. This exhibits superior ferroptosis-inducing effects with drug loading capacity and, importantly,...
At small scales, shape-programmable magnetic materials and self-sensing conductive have an enticing potential for realizing the functionalities that are unattainable by traditional machines. This work reports a facile preparation method of aself-sensing magnetism-responsive anisotropic films (SMAF) in which can be predesigned, oriented, patterned without requiring external field generator or other expensive devices. A variety shaped magnetoactive with complex chain-orientation structures...
Arsenic trioxide (As
Zero valent iron (ZVI) applications to remediation of shallow groundwaters can be affected by dissolved oxygen (DO) and organic ligands. To explore the intersection between these complicating factors, this study thoroughly characterized reactions nitrobenzene (NB) with ZVI in presence DO model ligand ethylene diamine tetraacetic acid (EDTA). The results showed that NB is degraded both reduction ZVI-induced advanced oxidation under oxygen-limited conditions. contribution ·OH degradation...
Abstract Electrical stimulation (ES) therapy accelerates cartilage healing but faces challenges due to bulky equipment, necessitating the development of a lightweight, implantable, and biocompatible electrical stimulator for improved patient compliance benefits. Piezoelectric materials have garnered considerable attention their potential as self‐driven bioelectric therapies treat osteoarthritis (OA) by providing in situ ES. Accordingly, an ES exercise‐driven regeneration based on...
Rheumatoid arthritis (RA) is an autoimmune disease whose pathophysiology closely related to inflammation-associated cells and the microenvironment of inflamed joints. This study aimed develop dual-targeted, reactive oxygen species (ROS)/pH dual-responsive, size-shrinkable intelligent micelles targeting M1 macrophages fibroblast-like synoviocytes (FLSs) enhance drug efficacy safety. These were surface-modified with PEG5000 prolong their circulation time in bloodstream hide molecules. The...
The relationship between childhood trauma and depression in early adulthood is complex influenced by factors such as resilience personality type. This study aims to investigate the mediating role of moderating types this relationship. A total 1059 undergraduates (mean age = 19.87 ± 1.82 years; 48.1% men, 51.9% women) were surveyed. Big Five Personality Inventory (BFI) was used assess dimensions participants, which further analyzed using latent profile analysis (LPA). Childhood experiences...
To establish an automated osteoporosis detection model based on low-dose abdominal CT (LDCT). This combined a deep learning-based automatic segmentation of the proximal femur with radiomics-based bone status classification. A total 456 participants were retrospectively included and divided into development cohort comprising 355 patients, 7:3 ratio randomly assigned to training validation cohorts, test 101 patients. The for was trained using VB-Net. Dice similarity coefficient (DSC) volume...
Feature extraction is a key part of the electronic tongue system. Almost all existing features methods are “hand-crafted”, which difficult in selection and poor stability. The lack automatic, efficient accurate has limited application development systems. In this work, convolutional neural network-based auto strategy (CNN-AFE) an (e-tongue) system for tea classification was proposed. First, sensor response e-tongue converted to time-frequency maps by short-time Fourier transform (STFT)....
Arsenene, a two-dimensional (2D) monoelemental layered nanosheet composed of arsenic, was recently reported to feature outstanding anticancer activities. However, the specific biological mechanism action remains unknown. In this work, we extensively analyzed arsenene in vivo and vitro discovered unexpected immune regulatory capability for first time. Analysis cell phenotypes tumor microenvironment by single-cell RNA sequencing revealed that remodeled recruiting high proportion cells...
Expression of a number steroid hormone and growth factor receptors is characteristic meningiomas. This paper reviews the analysis for progesterone, estrogen, androgen platelet derived (PDGF) in human meningioma tissue specimens. Progesterone receptor was assessed by Northern blot immunohistochemistry mRNA expressed 64% meningiomas examined. Immunohistochemical data correlated well with analysis. The staining clearly nuclear. more common from women than men. Analysis expression culture...
Two novel naphthalimide-piperazine-pyridine-based polystyrene solid-phase fluorescent sensors PS-NA and PS-ND with different lengths of the linker were synthesized shown to be able detect Hg(ii) ions. Their structures characterized by Fourier transform infrared (FTIR) spectroscopy scanning electron microscopy (SEM) analysis. Fluorescence properties, including response time, pH effects, fluorescence titration, metal ion selectivity regeneration, investigated compared. Sensor displayed a...
Magneto-sensitive soft materials that can accomplish fast, remote, and reversible shape morphing are highly desirable for practical applications including biomedical devices, robotics, flexible electronics. In conventional magneto-sensitive elastomers (MSEs), there is a tradeoff between employing hard magnetic particles with costly programming utilizing particle chains causing tedious small deformation. Here, inspired by the movement of mimosa, novel doped material bianisotropic elastomer...
Abstract Due to multidrug resistance and the high risk of recurrence, effective less toxic alternative pancreatic cancer treatments are urgently needed. Pancreatic cells highly resistant apoptosis but sensitive ferroptosis. In this study, an innovative nanoplatform ( AsIr@PDA ) was developed by electrostatic adsorption a cationic iridium complex IrFN onto two‐dimensional (2D) arsenene nanosheets. This exhibits superior ferroptosis‐inducing effects with drug loading capacity and, importantly,...
Abstract Ancient Chinese architecture drawing is a unique form of ancient art. Porcine blood hydrogels are distinctive ingredients used to prepare the composite material substrate layer for drawing. This investigation was focused on mechanism porcine hydrogel formation. Based traditional recipe preparation blood-lime mortar, samples with different ratios and lime water were prepared, molecular-scale interactions between proteins in examined FTIR spectroscopy, Raman XRD, XPS, fluorescence...