- Cannabis and Cannabinoid Research
- Palliative Care and End-of-Life Issues
- Pain Management and Opioid Use
- Opioid Use Disorder Treatment
- Childhood Cancer Survivors' Quality of Life
- Patient Dignity and Privacy
- Cancer survivorship and care
- Intestinal and Peritoneal Adhesions
- Cancer Immunotherapy and Biomarkers
- Pain Management and Placebo Effect
- Pediatric Pain Management Techniques
- Anesthesia and Pain Management
- Intraperitoneal and Appendiceal Malignancies
- Sleep and related disorders
- Epilepsy research and treatment
- Nausea and vomiting management
- Pharmacological Receptor Mechanisms and Effects
- Prenatal Substance Exposure Effects
- Colorectal Cancer Treatments and Studies
- Chemotherapy-related skin toxicity
- Lung Cancer Treatments and Mutations
- Pharmacological Effects and Toxicity Studies
- Economic and Financial Impacts of Cancer
- Bipolar Disorder and Treatment
- Health and Medical Research Impacts
Roswell Park Comprehensive Cancer Center
2017-2025
Velindre Cancer Centre
2024
University at Buffalo, State University of New York
2013-2022
Jacobs Institute
2020
VA Western New York Healthcare System
2013-2014
Hope Women's Cancer Centers
2013
The NCCN Guidelines for Palliative Care provide interdisciplinary recommendations on palliative care patients with cancer. These Insights summarize and context the updated guidelines regarding hospice end-of-life (EOL) care. Updates 2017 include revisions to restructuring of algorithms that address important EOL concerns. were revised clearer guidance oncologists as they cancer who are approaching transition Recommendations interventions reassessment based estimated life expectancy...
Palliative care has evolved to be an integral part of comprehensive cancer with the goal early intervention improve quality life and patient outcomes. The NCCN Guidelines for Care provide recommendations help primary oncology team promote best possible throughout illness trajectory each cancer. Panel meets annually evaluate update based on panel members' clinical expertise emerging scientific data. These Insights summarize panel's recent discussions highlights updates importance fostering...
Changes in postsurgical opioid prescribing practices may help reduce chronic use surgical patients.
Standardizing opioid management is challenging due to the absence of a ceiling dose, unknown ideal therapeutic plasma level, and lack an clear relationship between dose response. Opioid rotation or conversion, which switching from one opioid, route administration, both, another, improve response reduce toxicities, occurs in 20-40 percent patients treated with opioids. conversion often needed when there are adverse effects, inability tolerate certain formulation. A majority benefit leading...
Chronic obstructive pulmonary disease (COPD) is associated with a progressive course variable illness trajectory causing death either from respiratory failure or complications its comorbities. Palliative care benefits patients throughout all stages of COPD, goal to manage patients' symptom burden which can reduce physical, psychological, and social complications. Dyspnea the most common distressing end stage COPD experience, responds only partially therapy eventually becomes refractory...
Abstract Purpose Cannabis use may introduce risks and/or benefits among people living with cancer, depending on product type, composition, and nature of its use. Patient knowledge tetrahydrocannabinol (THC) or cannabidiol (CBD) concentration could provide information for providers about cannabis during after treatment that aide in risk benefit assessments. This study aimed to examine THC CBD patients cancer who consume cannabis, factors associated cannabinoid concentrations. Methods People...
Prescription opioids are used for managing pain in persons with cancer, however, there socioeconomic and racial disparities medication access. Cannabis is increasingly cancer symptom management as an opioid alternative. Limited data available about patterns of cannabis use among patients cancer. We survey from 4 National Cancer Institute-designated centers 3 states (n = 1220) to assess perceptions, pain, their substitution, ethnic differences each outcome. Compared White patients, Black were...
The psychiatric needs of those with cancer and other advanced illnesses are becoming increasingly recognized. Ketamine is emerging as a promising treatment option for depressive disorders in palliative care. In the care setting, its study has been hindered by lack consistent administration routes dosing. Intranasal (IN) esketamine (Spravato
Malignant wounds, often referred to as malignant cutaneous wounds or lesions, result from the proliferative, invasive, and destructive effects of neoplastic cells within skin supporting tissues. represent profoundly visible palpable stigmata advanced cancer. They are capable generating untold quantum multidimensional suffering for patient their caregivers. Thus, dealing with is highly complex challenging. Optimal outcomes may be achieved through adoption a whole approach opposed an that only...
Malignant bowel obstruction (MBO) is a complication of advanced malignancy. For inoperable patients, symptoms are often treated using analgesics, anticholinergics, and anti-emetics. There are, however, few published guidelines for the medical management MBO.To measure effect combination dexamethasone, octreotide, metoclopramide ("triple therapy") in patients with MBO, compared to who received none 3 medications ("no drug therapy").A retrospective cohort study MBO admitted single-center...