A5084013548- Smoking Behavior and Cessation
- Nicotinic Acetylcholine Receptors Study
- Behavioral Health and Interventions
- Cannabis and Cannabinoid Research
- Eating Disorders and Behaviors
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- HIV/AIDS Research and Interventions
- Stress Responses and Cortisol
- Tryptophan and brain disorders
- HIV-related health complications and treatments
- Biochemical Analysis and Sensing Techniques
- Olfactory and Sensory Function Studies
- HIV Research and Treatment
- Bariatric Surgery and Outcomes
- Religion, Spirituality, and Psychology
- Sleep and related disorders
- Neural and Behavioral Psychology Studies
- Mental Health Research Topics
- Functional Brain Connectivity Studies
- Coffee research and impacts
- Pain Management and Opioid Use
- Bipolar Disorder and Treatment
- Homelessness and Social Issues
- HIV, Drug Use, Sexual Risk
- Psychological and Temporal Perspectives Research
University at Buffalo, State University of New York
2007-2025
New York University
2025
University of Pennsylvania
2015-2024
Buffalo State University
2023
Philadelphia University
2005-2018
Yale University
2011
Increased preference for immediate over delayed rewards and risky certain has been associated with unhealthy behavioral choices. Motivated by evidence that enhanced cognitive control can shift choice behavior away from rewards, we tested whether training executive function could influence brain responses. In this randomized controlled trial, 128 young adults (71 male, 57 female) participated in 10 weeks of either a commercial web-based program or video games do not specifically target adapt...
Abstract Background and aims Mechanisms of varenicline preloading in promoting smoking abstinence have not been evaluated. Based on an extinction reinforcement framework, we tested the hypothesis that pre‐quit reductions rate mediate effect extended abstinence. We also alternative indicators change reinforcement, as well aversion, nausea self‐efficacy candidate mediators. Design, participants intervention Randomized, double‐blind, placebo‐controlled trial (NCT03262662) comparing (4‐week...
Stress and prefrontal cognitive dysfunction have key roles in driving smoking; however, there are no therapeutics for smoking cessation that attenuate the effects of stress on enhance cognition. Central noradrenergic pathways involved stress-induced reinstatement to nicotine executive control adaptive behaviors. We used a novel translational approach employing validated laboratory analogue stress-precipitated smoking, functional magnetic resonance imaging (fMRI), proof-of-concept treatment...
Abstract Background: As part of the Family Smoking Prevention and Tobacco Control Act, U.S. Food Drug Administration charged Products Scientific Advisory Committee with developing a report recommendations about effect menthol in cigarettes on public health. The purpose this study was to examine smoking behaviors, biomarkers exposure, subjective responses when switching from novel cigarette non-menthol isolate approximate ban might have smokers. Methods: Thirty-two adult smokers completed...
HIV-infected smokers lose more life years to tobacco use than HIV infection. The nicotine metabolite ratio (NMR), a biomarker of CYP2A6, represents individual variation in the rate at which is metabolized and associated with response smoking cessation treatments. We evaluated whether metabolize faster HIV-uninfected smokers, may contribute disproportionate burden have important treatment implications.We analysed baseline data from two clinical trials (NCT01710137; NCT01314001) compare NMR (N...
There is a critical need for the development of novel treatments nicotine dependence. Because majority smokers who make quit attempt fail within 7 days, medication screening procedures that focus on this early cessation period may provide an indicator treatment efficacy. To establish clinical validity paradigm, it to demonstrate association abstinence with longer-term abstinence. We tested number days during first week after target date (TQD) as predictor point prevalence in 3 independent...
Abstract Background The legal climate for cannabis use has dramatically changed with an increasing number of states passing legislation legalizing access medical and recreational use. Among cancer patients, is often used to ameliorate adverse effects treatment. Data are limited on the extent type among patients during treatment perceived benefits harms. This multicenter survey was conducted assess residing in varied cannabis. Methods A total 12 NCI-Designated Cancer Centers, across...
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Preclinical research and learning theory suggest that a longer duration of varenicline treatment prior to the target quit date (TQD) would reduce smoking rates before cessation improve abstinence outcomes. A double-blind randomized controlled trial tested this hypothesis in 60 smokers either an Extended run-in group (4 weeks pre-TQD varenicline) or Standard (3 placebo, 1 week varenicline); all participants received 11 post-TQD brief counseling. During pre-quit run-in, reduction was greater...
Introduction: The nicotine–metabolite ratio (NMR) predicts treatment response and is related to side effect severity. Sleep disturbance may be one important effect, but understanding sleep effects on smoking cessation complicated by the fact that nicotine withdrawal also produces disturbance. Aims: To evaluate of Methods: This a secondary analysis data from clinical trial (Lerman et al., 2015) 1,136 smokers randomised placebo ( n = 363), transdermal (TN; 381), or varenicline 392) stratified...