A5070644602- Reproductive Biology and Fertility
- Marine animal studies overview
- Coral and Marine Ecosystems Studies
- Marine and fisheries research
- Global Maternal and Child Health
- Estrogen and related hormone effects
- FOXO transcription factor regulation
- Dialysis and Renal Disease Management
- Nanoparticles: synthesis and applications
- Isotope Analysis in Ecology
- Aquaculture disease management and microbiota
- Nutrition, Genetics, and Disease
- CRISPR and Genetic Engineering
- Health and Wellbeing Research
- Underwater Acoustics Research
- Fish Biology and Ecology Studies
- Assisted Reproductive Technology and Twin Pregnancy
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Drug Transport and Resistance Mechanisms
- Maternal and Neonatal Healthcare
- Marine Bivalve and Aquaculture Studies
- Sperm and Testicular Function
- Consumer Attitudes and Food Labeling
- Genetic Syndromes and Imprinting
- Reproductive biology and impacts on aquatic species
Showa University
2025
Tokyo University of Pharmacy and Life Sciences
2012-2023
Waseda University
2022-2023
Utsunomiya University
2023
The University of Tokyo
1990-2022
Obihiro University of Agriculture and Veterinary Medicine
2006-2022
Kitasato University
2020-2021
Center for Global Health
2021
National Center for Global Health and Medicine
2021
Chukyo University
2021
Plastics have benefited our lives in many ways, but their long persistence the environment causes serious problems. Rapid decomposition and detoxification of plastics after use are significant challenges. As a possible solution, biodegradable attracted attention, for environmental risk assessment research on polymer toxicity, indicator organisms, like water fleas fish, has increased globally. However, such often focuses standardized substances without considering changes toxicity due to...
Cytomegalovirus (CMV) can cause life-threatening diseases in immunosuppressed patients. Some of the patients with connective tissue disease develop CMV infection, and approximately half this group has been reported to have received pulsed-methylprednisolone (p-MPSL) therapy. This study aimed identify predictors onset infection receiving p-MPSL therapy for disease. was a retrospective, multicenter cohort study. We included who had antigenemia measured between April 2011 December 2020....
Endozoicomonas bacteria symbiosis with various marine organisms is hypothesized as a potential indicator of health in corals. Although many amplicon analyses using 16S rRNA gene have suggested the diversity species, genome analysis has been limited due to contamination host-derived sequences and difficulties culture metagenomic analysis. Therefore, evolutionary functional individual species symbiotic same coral remains unresolved. In this study, we applied novel single-cell genomics...
ESR Endangered Species Research Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout JournalEditorsSpecials 26:137-146 (2014) - DOI: https://doi.org/10.3354/esr00637 Recognition of juvenile hawksbills Eretmochelys imbricata through face scale digitization and automated searching S. G. Dunbar1,2,3,6,*, H. E. Ito4, K. Bahjri5, Dehom5, L. Salinas6 1Marine Group, Department Earth Biological Sciences, Loma Linda University,...
The effects of Ti, Nb, Ta, Zr, and Ag on cellular bacterial adhesion were investigated in this study. Moreover, the relationships between surface compositions, metal ion release behaviors, biological responses examined. As a result, MC3T3-E1 cells S. aureus able to better attach Ti Zr rather than Nb Ta specimens. For specimen, amount ions released into Hanks’ solution was largest among all Cellular onto specimen inhibited compared with other specimens, because release. Alternatively,...
Journal Article Critical role of farnesoid X receptor for hepatocellular carcinoma cell proliferation Get access Tomofumi Fujino, Fujino * 1School Pharmacy, Tokyo University Pharmacy and Life Science; 2Department Radiopharmacy, Tohoku Pharmaceutical University; 3Department Biological Sciences, Graduate School Bioscience Biotechnology, Institute Technology; 4The National Health Sciences; 5Department Applied Chemistry, Agricultural The Tokyo, Japan *Tomofumi Science, 1432-1 Horinouchi,...
ABSTRACT Much is known about lunge feeding in balaenopterid whales, but many key aspects of structure, function, and behavior have not yet been explained detail, especially with regard to concentrating, positioning, swallowing large aggregations prey. We describe a novel system three integrated structural components, all which are involved sequential activities (intraoral transport, filtration, prey) that follow lunge‐feeding engulfment prey‐laden water rorquals: (1) hammock‐like muscular...
Abstract Forkhead box L2 (FOXL2) plays a critical role in the development and function of mammalian ovaries. In fact, causative effects FOXL2 misregulations have been identified many ovarian diseases, such as primary insufficiency granulosa cell tumor; however, mechanism by which expression is regulated not well studied. Here, we showed that mural cells (MGCs) requires stimulation both oocyte-derived signals estrogen mice. absence oocytes or estrogen, its transcriptional targets, Cyp19a1 Fst...
Abstract Cumulus cells and mural granulosa (MGCs) play distinct roles during follicular development, normal development of these cell lineages is critical for the female fertility. Transcriptomic diversification between two obviously a mechanism their functional diversification; however, transcriptional regulators responsible this event have not been fully defined. In study, we sought to identify key differential gene expression lineages. silico analysis transcriptomic comparison cumulus...
Omics analysis is a versatile approach for understanding the conservation and diversity of molecular systems across multiple taxa. In this study, we compared proteome expression profiles four yeast species (Saccharomyces cerevisiae, Saccharomyces mikatae, Kluyveromyces waltii, lactis) grown on glucose- or glycerol-containing media. Conserved changes all were observed only small proportion proteins differentially expressed between two growth conditions. Two species, both which exhibited high...
Abstract Although genetically modified mice can be generated with high efficiency by using CRISPR/Cas9-mediated genome editing in mouse zygotes, only the loci a protospacer-adjacent motif (PAM) sequence are targetable. The present study investigated usability of engineered Streptococcus pyogenes Cas9 (SpCas9-NG) zygotes. In addition to 5′-NGG sequence, SpCas9-NG recognized 5′-NGA, 5′-NGC and 5′-NGT sequences zygotes as PAMs that were appropriate for generation knockout mice. Moreover,...
The farnesoid X receptor (FXR) is a bile acid-activated nuclear which abundant in the liver, intestine, and kidney. FXR pivotal factor cholesterol/bile acid homeostasis but involved growth of hepatocellular carcinoma cells. In present study, we investigated whether also renal adenocarcinoma cell line ACHN was inhibited by knockdown stimulated ligand, while that normal cell-derived line, HK-2, not affected. carcinoma-specific stimulation found to arise from down-regulation p53 p21/Cip1 mRNA...
The cooperative effects of estrogen and oocyte-derived paracrine factors (ODPFs) play critical roles in the normal development ovarian follicles; however, mechanism underlying this cooperation has not been well studied. present study aimed to determine whether ODPFs affect signaling by regulating expression receptor (ESR) its coregulators mouse granulosa cells. Some transcripts encoding ESR were differentially expressed between cumulus mural cells (MGCs). transcript levels coregulators,...
Sexual differentiation in Bombyx mori is controlled by sex-specific splicing of Bmdsx, which results the omission exons 3 and 4 a male-specific manner. In B. mori, insulin-like growth factor II mRNA-binding protein (Imp) involved Bmdsx. Male-specific Imp mRNA from inclusion exon 8. To verify link between histone methylation alternative RNA processing Imp, we examined effects RNAi-mediated knockdown several methyltransferases on expression Imp. As result, was completely abolished when H3K79...
Mandibular mobility accompanying gape change in Northern and Antarctic minke whales was investigated by manipulating jaws of carcasses, recording jaw movements via digital instruments (inclinometers, accelerometers, goniometers), examining osteological soft tissue computed tomography (CT)-scans. We longitudinal (α) rotation the mandible mediolateral displacement at symphysis (Ω1 ) temporomandibular joint (Ω2 as mouth opened (Δ). Results indicated three phases opening. In first phase,...
1 College of Bioresource Sciences, Nihon University, Fujisawa, Kanagawa 252-0880, Japan 2 Prefectural Museum Natural History, Odawara, 250-0031, 3 Yokohama Hakkeijima Sea Paradise, Yokohama, 236-0006, 4 National Research Institute Fisheries Science, Agency, 236-8648, 5 Driftological Society, Hata, Kochi 789-1911,