Guo‐Ming Zhang

ORCID: 0000-0003-0662-1302
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Research Areas
  • Cancer-related molecular mechanisms research
  • MicroRNA in disease regulation
  • Circular RNAs in diseases
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Lipoproteins and Cardiovascular Health
  • Theoretical and Computational Physics
  • Vestibular and auditory disorders
  • Nanofabrication and Lithography Techniques
  • RNA modifications and cancer
  • Blood groups and transfusion
  • X-ray Diffraction in Crystallography
  • Force Microscopy Techniques and Applications
  • Crystallization and Solubility Studies
  • Hemoglobinopathies and Related Disorders
  • Epigenetics and DNA Methylation
  • Clinical Laboratory Practices and Quality Control
  • Liver Disease Diagnosis and Treatment
  • Hemodynamic Monitoring and Therapy
  • Liver Disease and Transplantation
  • Opinion Dynamics and Social Influence
  • Adipokines, Inflammation, and Metabolic Diseases
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Complex Network Analysis Techniques
  • Extracellular vesicles in disease
  • Regulation of Appetite and Obesity

Xuzhou Medical College
2016-2024

Qilu Hospital of Shandong University
2021-2024

Qinghai University
2024

Beijing Normal University
2020-2024

Shaoxing People's Hospital
2024

First Affiliated Hospital of Xiamen University
2019-2022

Xiamen University
2021

Zunyi Medical University
2020-2021

Gaochun People's Hospital
2020

Xinjiang Medical University
2017

Winging it: The natural micro- and nanostructures that exist on the wings of cicadas (see image) are used as a new type nanoimprinting lithography (NIL) stamp. NIL is to fabricate nanowell arrays structures transferred silicon substrate by reactive ion etching. Patterned PMMA (poly(methyl methacrylate)) also mold hexagonal gold pillar mimick cicada wings. This work demonstrates use much cheaper method abundant easy obtain. Supporting information for this article available WWW under...

10.1002/smll.200600255 article EN Small 2006-10-06

Numerous studies have shown that the hematological components of systemic inflammatory response, including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR), lymphocyte-to-monocyte (LMR), and immune inflammation index (SII) are efficient prognostic indicators in patients with cancers. Most did not investigate reference intervals (RIs) these parameters healthy controls.A retrospective cohort study was performed on ethnic Han population aged between 18 79 years age by...

10.7754/clin.lab.2018.180715 article EN Clinical Laboratory 2019-01-01

Desertification is a form of land degradation principally in semi-arid and arid areas influenced by climatic human factors. As country plagued extensive sandy desertification frequent sandstorms dust storms, China has been trying to find ways achieve the sustainable management desertified lands. This paper reviewed impact climate change anthropogenic activities on areas, effort, outcome, lessons learned from control China. Although drying warming trends growing population pressures exist...

10.3390/su12083258 article EN Sustainability 2020-04-17

This paper describes a paradigm, simple, low-cost and conventional approach to the fabrication of large-area subwavelength anti-reflective nanostructures on films directly with bio-template. Specifically, nano-nipple arrays surface cicada wings have been precisely replicated PMMA (polymethyl methacrylate) film high reproducibility by technique replica molding, which mainly involves two processes: one is that negative Au mold prepared from bio-template wing thermal deposition; other used...

10.1088/0957-4484/19/9/095605 article EN Nanotechnology 2008-02-12

The single-spin-flip Metropolis Monte Carlo algorithm is applied to an Ising ferromagnet with mixed spins of S=1/2 and S=1 a crystal-field interaction. critical temperatures exponents both in the absence presence interaction are investigated finite-size scaling theory. temperature that we obtained zero crystal field very close high-temperature series-expansion result. results for yield two-dimensional Ising-model values, which good agreement those suggested by universality hypothesis. phase...

10.1103/physrevb.48.9452 article EN Physical review. B, Condensed matter 1993-10-01

Pancreatic head cancer (PHC) and pancreatic body/tail (PBTC) have distinct clinical biological behaviors. The microbial metabolic differences in PHC PBTC not been studied. microbiota metabolome of 15 8 tissues their matched nontumor were characterized using 16S rRNA amplicon sequencing untargeted metabolomics. At the genus level, Bradyrhizobium was increased while Corynebacterium Ruminococcus decreased (Head T) compared with N) significantly. Shuttleworthia, Bacillus, Bifidobacterium...

10.1111/cas.16238 article EN cc-by-nc-nd Cancer Science 2024-06-18

Abstract Background Small songbirds respond and adapt to various geographical barriers during their annual migration. Global flyways reveal the diverse migration strategies in response different barriers, among which are high-elevation plateaus. However, few studies have been focused on largest highest plateau world, Qinghai–Tibet Plateau (QTP) poses a significant barrier migratory passerines. The present study explored routes of population Siberian Rubythroats ( Calliope calliope ) that...

10.1186/s40462-024-00495-5 article EN cc-by Movement Ecology 2024-08-01

Dotting the i's: Stimuli-responsive optoelectronic devices are formed from title transistors functionalized with photoactive quantum dots. The p-type semiconducting tubes show a fast current decrease under UV irradiation and reversibility when is switched off. In contrast, ambipolar mirror-image photoswitching effects negative positive gate bias voltages applied.

10.1002/anie.200901018 article EN Angewandte Chemie International Edition 2009-05-19

The 5-hydroxytryptamine 2C (5-HT<sub>2C</sub>) receptor subtype has received considerable attention as a target for drug discovery, having been implicated in wide variety of disorders. Here, we describe the vitro pharmacological profile novel 5-HT<sub>2C</sub> receptor-selective agonist vabicaserin [(−)-4,5,6,7,9,9a,10,11,12,12a-decahydrocyclopenta[c] [1,4]diazepino[6,7,1-ij]quinoline hydrochloride] (SCA-136), including comprehensive strategy to assess 5-HT<sub>2B</sub> selectivity using...

10.1124/jpet.111.179572 article EN Journal of Pharmacology and Experimental Therapeutics 2011-03-14

Prolonged hyperglycemia is an important risk factor of the pathogenesis diabetic retinopathy (DR). Extracellular matrix molecules, such as fibronectin, collagen IV, and laminin, are associated with fibrotic membranes. In this study, we investigated expression laminin in RPE cells under high glucose conditions. Furthermore, also detected phosphorylation protein kinase B (Akt) conditions cells. Our results showed that upregulated expression, activated Akt We found pretreatment LY294002 (an...

10.1155/2015/920280 article EN cc-by Journal of Diabetes Research 2015-01-01

To characterize the regulatory effect of gammadelta T cells in activation IL-17+ uveitogenic cells.The authors administered TCR-specific antibody GL3 to B6 mice before or after antigen immunization and examined Th1- Th17-polarized T-cell responses. The intensity Th17 responses was also responder containing varying numbers cells.GL3 treatment resulted degrees depletion circulating cells, depending on when administered. alphabetaTCR+IL-17+, but not alphabetaTCR+IFN-gamma+, IRBP-specific...

10.1167/iovs.09-5045 article EN Investigative Ophthalmology & Visual Science 2010-04-07

Background:The aim of this study was to establish the reference intervals (RIs) total bilirubin (TBIL), alanine aminotransferase (ALT), aspartate transaminase (AST), and creatinine (CREA) for apparently healthy elderly (Han ethnicity) in Shuyang, China. Material/Methods:A 54 912 blood specimens from residents age 65-104 years were collected by standard procedures Shuyang county Jiangsu province.TBIL, ALT, AST, CREA each participant determined automatic biochemical analyzer.Distribution...

10.12659/msm.892148 article EN Medical Science Monitor 2014-01-01

The authors report herein a new type of nanonipple structures on the cicada’s eye and direct structural replication complex micro- nanostructures for potential functional emulation. A two-step molding process is developed to replicate these natural using epoxy resin with high fidelity, which demonstrates general way fabricating by biotemplates via suitable physicochemical process. Measurements spectral reflectance showed that this kind replicated nanostructure has remarkable antireflective...

10.1063/1.2715094 article EN Applied Physics Letters 2007-03-19

BACKGROUND:The aim of this study was to calculate 95% reference intervals and double-sided limits serum alpha-fetoprotein (AFP) carcinoembryonic antigen (CEA) according the CLSI EP28-A3 guideline. MATERIAL AND METHODS:Serum AFP CEA values were measured in samples from 26 000 healthy subjects Shuyang area receiving general health checkups. The upper calculated by using MedCalc. RESULTS:We provided continuous 20 years old 90 for CEA. were: AFP, 1.31–7.89 ng/ml (males) 1.01–7.10 (females); CEA,...

10.12659/msm.901861 article EN Medical Science Monitor 2016-12-12

Background: LDLC equations have varying levels of underestimation for the calculated LDLC. Therefore, underestimating should be avoided as much possible. We need to establish that underestimate little Methods: established with a healthy cohort from Shuyang Hospital and validated an unselected patient The Second People's Lianyungang. novel by using regression equation. relationship between two markers was analysed Pearson's approach. 95% limits measuring agreement within ± 2 SD performed...

10.2147/ijgm.s451743 article EN cc-by-nc International Journal of General Medicine 2024-02-01

BACKGROUND The aim of this study was to investigate the incidence and related risk factors new silent cerebral infarction in patients with acute non-cerebral amyloid angiopathy (non-CAA) intracerebral hemorrhage (ICH) explore clinical cerebrovascular event recurrence within 1 year. MATERIAL AND METHODS This prospective observed 152 non-CAA ICH diagnosed by computed tomography 3 days after onset. All underwent magnetic resonance imaging on day 14 identify infarction, their subsequent events...

10.12659/msm.914423 article EN Medical Science Monitor 2019-01-14
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