A5028776351- Porphyrin and Phthalocyanine Chemistry
- Nanoplatforms for cancer theranostics
- Luminescence and Fluorescent Materials
- Photodynamic Therapy Research Studies
- Nerve injury and regeneration
- Polymer composites and self-healing
- 3D Printing in Biomedical Research
- Carbon dioxide utilization in catalysis
- Supramolecular Chemistry and Complexes
- Microfluidic and Bio-sensing Technologies
- Proteoglycans and glycosaminoglycans research
- Microplastics and Plastic Pollution
- Boron and Carbon Nanomaterials Research
- Advanced Biosensing Techniques and Applications
- Graphene and Nanomaterials Applications
- Dyeing and Modifying Textile Fibers
- Education Practices and Challenges
- Environmental Chemistry and Analysis
- Cultural and Sociopolitical Studies
- biodegradable polymer synthesis and properties
- Fermentation and Sensory Analysis
- Glycosylation and Glycoproteins Research
- Advanced biosensing and bioanalysis techniques
- Neuroscience and Neural Engineering
- Electrohydrodynamics and Fluid Dynamics
École Polytechnique Fédérale de Lausanne
2022-2025
Bilkent University
2019-2020
Peripheral nerve damage results in the loss of sensorimotor and autonomic functions, which is a significant burden to patients. Furthermore, injuries greater than limiting gap length require surgical repair. Although autografts are preferred clinical choice, their usage impeded by limited availability, dimensional mismatch, sacrifice another functional donor nerve. Accordingly, guidance conduits, tubular scaffolds engineered provide biomimetic environment for regeneration, have emerged as...
Transmission of viruses through contact with contaminated surfaces is an important pathway for the spread infections. Antiviral surface coatings are useful to minimize such risks. Current state-of-the-art approaches toward antiviral either involve metal-based materials or complex synthetic polymers. These approaches, however, even if successful, will have face great challenges when it comes large-scale applications and their environmental sustainability. Here, coating was prepared by...
The herpes simplex virus (HSV) is associated with serious conditions, such as encephalitis and blindness, its infection closely linked to significant vascular complications coagulation issues, particularly in individuals compromised immune systems. Current antiviral treatments often fall short of effectively eliminating viral shedding face resistance are not entirely effective managing coagulation. HSV recognition heparan sulfate on cell walls for entry well-established. A possible strategy...
Abstract The development of mechanically robust, chemically stable, and yet recyclable polymers represents an essential undertaking in the context advancing a circular economy for plastics. Here, we introduce novel cleavable β‐(1,3‐dioxane)ester ( DXE ) linkage, synthesized through catalyst‐free reaction β‐ketoester 1,3‐diol, to cross‐link poly(vinyl alcohol) PVA formation high‐performance thermosets with inherent chemical recyclability. , modified groups transesterification excess tert...
Here we report a photoactive supramolecular assembly that is multifunctional and constructed by covalently linking four receptor molecules (cucurbit[7]uril) to porphyrin derivative with suitable linkers. While this molecular platform serves very efficiently as light-triggered broad-spectrum antibacterial agent, owing its negligible dark cytotoxicity the presence of host (CB7), it can also be utilized vehicle carry drug for combined chemo photodynamic cancer therapy.
A [5]rotaxane was synthesized through a catalytically self‐threading reaction in which CB6 serves as macrocycle and acts catalyst for the 1,3‐dipolar cycloaddition between alkyne substituted porphyrin core azide functionalized stopper groups by forming triazole. Application of this rotaxane photosensitizer photodynamic therapy against cancer cells bacteria inactivation have also been demonstrated. This has an excellent water solubility remains stable biological media at physiological pH...
Under the simultaneous use of pressure-driven flow and DC electric field, migration particles inside microfluidic channels exhibits intricate focusing dynamics. Available experimental analytical studies fall short in giving a thorough explanation to particle equilibrium states. Also, understanding is so far limited results based on Newtonian neutral viscoelastic carrier fluids. Hence, holistic approach taken this study elaborate interplay governing electrophoretic slip-induced/elastic/shear...
Herein, hybrid nanoparticles composed of a red-emitting conjugated oligomer (COL) and gold (Au-NPs) were prepared through one-pot synthetic method in which the acts as reducing agent well matrix to wrap newly formed Au nanoparticles. These (COL-Au-NPs) exhibited photodynamic photothermal activity against both Gram-positive Gram-negative bacterial strains. They also proven possess high photostability thermal reversibility. Dark cytotoxicity COL-Au-NPs toward pathogens mammalian breast cancer...
Porphyrin derivatives are highly attractive in the construction of multifunctional molecular platforms with interesting properties and applications. In this regard, we report here use a porphyrin-based platform as photosensitizer for photodynamic therapy drug carrier. This was constructed by conjugating host molecule, cucurbit[7]uril to triglycosylated tetraphenyl porphyrin serves very efficiently inactivation both gram-negative (Escherichia coli, E. coli) gram-positive bacteria (Bacillus...
Antimicrobial surfaces limit the spread of infectious diseases. To date, there is no antimicrobial coating that has widespread use because short-lived and limited spectrum efficacy, poor resistance to organic material, and/or cost. Here, we present a paint based on waterborne latex particles supramolecularly associated with quaternary ammonium compounds (QACs). The optimal supramolecular pairing was first determined by immobilizing selected ions self-assembled monolayers exposing different...
Here, we adapt the catalytically self-threading polyrotaxane synthesis for construction of two-dimensional polymeric thin films using a water–oil interfacial polymerization method. In this method, and rotaxane formation take place simultaneously at interface because presence active cucurbit[6]uril (CB6) that can facilitate 1,3-dipolar cycloaddition reaction between alkyne azide to form polytriazoles. By varying concentration monomers, time, size vessel, it is possible control thickness...
Abstract The development of mechanically robust, chemically stable, and yet recyclable polymers represents an essential undertaking in the context advancing a circular economy for plastics. Here, we introduce novel cleavable β‐(1,3‐dioxane)ester ( DXE ) linkage, synthesized through catalyst‐free reaction β‐ketoester 1,3‐diol, to cross‐link poly(vinyl alcohol) PVA formation high‐performance thermosets with inherent chemical recyclability. , modified groups transesterification excess tert...