A5102834963- Dialysis and Renal Disease Management
- Renal Diseases and Glomerulopathies
- Vasculitis and related conditions
- Iron Metabolism and Disorders
- Chronic Kidney Disease and Diabetes
- Renal function and acid-base balance
- Nutrition and Health in Aging
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Erythropoietin and Anemia Treatment
- Clinical Nutrition and Gastroenterology
- Neurological and metabolic disorders
- Pharmacological Effects and Toxicity Studies
- Health, Medicine and Society
- Central Venous Catheters and Hemodialysis
- Acute Kidney Injury Research
- Systemic Lupus Erythematosus Research
- Muscle and Compartmental Disorders
- Complement system in diseases
- Potassium and Related Disorders
- Ion Transport and Channel Regulation
- Blood Pressure and Hypertension Studies
- Electrolyte and hormonal disorders
- Nephrotoxicity and Medicinal Plants
- Healthcare Systems and Practices
- Adrenal Hormones and Disorders
Inserm
2020-2023
Centre Hospitalier de Vitré
2013-2023
Hôpital Ambroise-Paré
2023
Université de Versailles Saint-Quentin-en-Yvelines
2023
Centre de recherche en Epidémiologie et Santé des Populations
2020-2023
Université Paris-Saclay
2023
Centre Hospitalier de Béthune
2013
Université Paris-Est Créteil
2013
Service de la Santé Publique
2002
Hôpital Pellegrin
2001
Although intradialytic parenteral nutrition (IDPN) is a method used widely to combat protein-calorie malnutrition in hemodialysis patients, its effect on survival has not been thoroughly studied. We conducted prospective, randomized trial which 186 malnourished patients received oral nutritional supplements with or without 1 year of IDPN. IDPN did improve 2-year mortality (primary end point), hospitalization rate, Karnofsky score, body mass index, laboratory markers status. Instead, both...
Background. Protein-energy wasting is a frequent and debilitating condition in maintenance dialysis. We randomly tested if an energy-dense, phosphate-restricted, renal-specific oral supplement could maintain adequate nutritional intake prevent malnutrition haemodialysis patients with insufficient intake. Methods. Eighty-six were assigned to standard care (CTRL) group or prescribed two 125-ml packs of Renilon 7.5® daily for 3 months (SUPP). Dietary intake, serum (S) albumin, prealbumin,...
Background Previous small studies have reported favorable results of peritoneal dialysis (PD) in the setting chronic refractory heart failure (CRHF). We evaluated impact PD a larger cohort patients with CHRF where end-stage renal disease was excluded. Methods All who received therapy for CRHF between January 1995 and December 2010 two medical centers France were included this retrospective study. Baseline characteristics compared clinical parameters during first year after initiation PD....
Gitelman syndrome (GS) is a tubulopathy caused by SLC12A3 gene mutations, which lead to hypokalaemic alkalosis, secondary hyperaldosteronism, hypomagnesaemia and hypocalciuria.The aim of this study was assess the prevalence mutations in adult patients; compare phenotype homozygous, heterozygous non-mutated determine efficiency treatment.Clinical, biological genetic data were recorded 26 patients.Screening for detected two 15 patients (six homozygous nine compound heterozygous), one mutation...
ABSTRACT Background Conservative care is increasingly considered an alternative to kidney replacement therapy for failure management, mostly among the elderly. We investigated its status and barriers implementation from patients’ providers’ perspectives. Methods analysed data 1204 patients with advanced chronic disease (CKD) [estimated glomerular filtration rate (eGFR) <30 mL/min/1.73 m2] enrolled at 40 nationally representative nephrology clinics (2013–16) who completed a...
El fallo dictado recientemente por la Corte Suprema de Provincia Catamarca nos invita a analizar efectiva tutela del ambiente en el contexto una acción amparo entablada cacique Comunidad Originaria Atacameños Altiplano. Mediante esta se solicitó medida cautelar con objetivo que ordene suspensión actividad minera desplegada localidad Antofagasta Sierra desde año 1997, considerar los permisos y autorizaciones fueron otorgados violación las normas rigen materia ambiental minera. Entre...
Data regarding the incidence and outcome of renal involvement in patients with inflammatory myopathies (IM) remain scarce. We assessed causes acute kidney injury (AKI) chronic disease (CKD) 150 dermatomyositis, polymyositis, antisynthetase syndrome followed 3 French referral centers. Renal occurred 35 (23.3%) patients: AKI 16 (10.7%), CKD 31 (20.7%) patients. The main cause was drug or myoglobinuria-induced tubular necrosis. Male sex, cardiovascular risk factors, cardiac involvement, initial...
ABSTRACT In a cross‐sectional study of more than 30% French dialysis patients ( N = 7,123), we evaluated the relationships between predialysis plasma bicarbonate concentration and nutritional markers. Data including age, gender, cause end‐stage renal disease (ESRD), time on dialysis, body mass index (BMI), blood levels midweek albumin, prealbumin, were collected. Normalized protein catabolic rate (nPCR), adequacy parameters, estimation lean (LBM) computed from pre‐ postbicarbonate‐dialysis...
Home telemonitoring has developed considerably over recent years in chronic diseases order to improve communication between healthcare professionals and patients promote early detection of deteriorating health status. In the nephrology setting, home been evaluated dialysis but data are scarce concerning kidney disease (CKD) before after renal replacement therapy. The eNephro study is designed assess cost effectiveness, clinical/biological impact, patient perception a for CKD patients. Our...
<b><i>Background:</i></b> Pauci-immune glomerulonephritis (PIGN) is a major prognostic factor in antineutrophil cytoplasmic antibodies-associated vasculitis (AAV). Renal remission usually defined as improvement or stabilization of serum creatinine and proteinuria levels but the significance hematuria unclear. We evaluated value microscopic patients from first flare PIGN. <b><i>Methods:</i></b> A multicenter retrospective study was conducted all...
Chronic kidney disease (CKD) is associated with an elevated risk of neurocognitive disorders (NCDs). It remains unclear whether CKD-related NCDs have a specific cognitive pattern or are earlier-onset phenotypes the main (vascular and Alzheimer's disease).
Kynurenine is a protein-bound uremic toxin. Its circulating levels are increased in chronic kidney disease (CKD). Experimental studies showed that it exerted deleterious cardiovascular effects. We sought to evaluate an association between serum kynurenine and adverse fatal or nonfatal events all-cause mortality CKD patients. The CKD-REIN study prospective cohort of people with having estimated glomerular filtration rate (eGFR) <60 ml/min/1.73 m². Baseline frozen samples total free fractions...