Akira Hayakawa

ORCID: 0000-0003-0727-8040
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About
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Research Areas
  • Childhood Cancer Survivors' Quality of Life
  • Acute Lymphoblastic Leukemia research
  • Hematopoietic Stem Cell Transplantation
  • Family Support in Illness
  • Acute Myeloid Leukemia Research
  • Palliative Care and End-of-Life Issues
  • Immune Cell Function and Interaction
  • Nutrition and Health in Aging
  • Family and Disability Support Research
  • Adolescent and Pediatric Healthcare
  • Platelet Disorders and Treatments
  • Virus-based gene therapy research
  • Renal Diseases and Glomerulopathies
  • Meningioma and schwannoma management
  • Oral health in cancer treatment
  • Sarcoma Diagnosis and Treatment
  • Blood groups and transfusion
  • Alkaline Phosphatase Research Studies
  • Bone health and treatments
  • Healthcare cost, quality, practices
  • Ovarian cancer diagnosis and treatment
  • Parvovirus B19 Infection Studies
  • Autoimmune and Inflammatory Disorders Research
  • Polyomavirus and related diseases
  • Brain Metastases and Treatment

Yodogawa Christian Hospital
2018-2022

Kobe University
1999-2022

Nagasaki University
1972

The aim of the study was to clarify relationship between current pet ownership, passive smoking, and allergic diseases among Japanese children. From 1995 2001, we distributed edition questionnaire American Thoracic Society Division Lung Diseases (ATS‐DLD) survey 35,552 6‐yr‐old children at primary school in city Himeji, Japan. We analyzed data by multiple logistic regression calculated adjusted odds ratios for environmental factors, including smoking (dog and/or cat) ownership. There were no...

10.1111/j.1399-3038.2005.00342.x article EN Pediatric Allergy and Immunology 2005-12-20

Abstract Background Quality of life ( QOL ) as a treatment outcome has not yet been evaluated among patients receiving specific regimen by phase in consistent manner. This exploratory cross‐sectional study the children with acute lymphoblastic leukemia ALL one most popular regimens Japan (Japan Association Childhood Leukemia Study ‐02 revised protocol). Methods Children aged 5–18 years newly diagnosed B‐cell precursor were included. The Pediatric Life Inventory ™ 4.0 Generic Core Scales...

10.1111/ped.13092 article EN Pediatrics International 2016-07-16
Koji Amano Hiroto Ishiki Tomofumi Miura Isseki Maeda Yutaka Hatano and 95 more Shunsuke Oyamada Naosuke Yokomichi Keita Tagami Takuya Odagiri Tetsuya Ito Mika Baba Tatsuya Morita Masanori Mori Satoshi Inoue Kengo Imai Hiroaki Tsukuura Toshihiro Yamauchi Akemi Shirado Naito Yu Uneno Akira Yoshioka Shuji Hiramoto Ayako Kikuchi Tetsuo Hori Yosuke Matsuda Hiroyuki Kohara Hiromi Funaki Keiko Tanaka Kozue Suzuki Tina Kamei Yukari Azuma Teruaki Uno Jiro Miyamoto Hirofumi Katayama Hideyuki Kashiwagi Eri Matsumoto Kiyofumi Oya Takeya Yamaguchi Tomonao Okamura Hoshu Hashimoto Shunsuke Kosugi Nao Ikuta Yaichiro Matsumoto Takashi Ohmori Takehiro Nakai Takashi Ikee Yuto Unoki Kazuki Kitade Shu Koito Nanao Ishibashi Masaya Ehara Kosuke Kuwahara Shohei Ueno Shunsuke Nakashima Yuta Ishiyama Akihiro Sakashita Ryo Matsunuma Hana Takatsu Takashi Yamaguchi Satoko Ito Toru Terabayashi Jun Nakagawa Tetsuya Yamagiwa Akira Inoue Takuhiro Yamaguchi Mitsunori Miyashita Saran Yoshida Yusuke Hiratsuka Hiroaki Watanabe Masayuki Ikenaga Keiji Shimizu Akira Hayakawa Rena Kamura Takeru Okoshi Tomohiro Nishi Kazuhiro Kosugi Yasuhiro Shibata Takayuki Hisanaga Takahiro Higashibata Ritsuko Yabuki Shingo Hagiwara Miho Shimokawa Satoshi Miyaké Junko Nozato Tetsuji Iriyama Keisuke Kaneishi Yoshihisa Matsumoto Ayumi Okizaki Yuki Watanabe Yuko Uehara Eriko Satomi Kaoru Nishijima Junichi Shimoinaba Ryoichi Nakahori Takeshi Hirohashi Jun Hamano Natsuki Kawashima Takashi Kawaguchi Megumi Uchida Ko Sato Yoichi Matsuda

Background: Limited information is available on the relationship between C-reactive protein (CRP) levels and pain in advanced cancer. Objectives: To investigate serum of CRP subtypes pain. Design: A secondary cross-sectional analysis a prospective cohort study. Setting/Subjects: Patients with cancer admitted to 23 palliative care units Japan. Measurements: rated severity numerical rating scale (NRS) physicians evaluated integrated outcome (IPOS). Physicians assessed neuropathic breakthrough...

10.1089/pmr.2021.0004 article EN cc-by-nc Palliative Medicine Reports 2021-05-01

Abstract Background Childhood cancer survivors lacking awareness on their potential risks of late effects often fail to seek adequate follow-up care. Patient education matching preference is great importance improve adherence survivorship In this study, we developed two age-dependent game-based learning programs, which enable continuous approaches for childhood along intellectual maturation. Then, assessed the effectiveness programs. Methods over 10 years age who regularly visited a...

10.1186/s12885-022-09359-w article EN cc-by BMC Cancer 2022-03-29

There are very few reliable and valid measures in Japan assessing health-related quality of life (HRQOL) children with cancer. The present study aimed to develop a Japanese version the Minneapolis-Manchester Quality Life Survey Health Adolescent Form (MMQL-AF), which is measure for HRQOL childhood cancer survivors, investigate its reliability validity.Participants were 141 who had been off therapy more than one year 183 healthy controls. internal consistency assessed through test-retest...

10.1186/s12955-014-0127-y article EN cc-by Health and Quality of Life Outcomes 2014-08-14

1995-2009年に20歳未満で自家/同種造血幹細胞移植(HSCT)を受け,2年以上無治療で生存している患者に対して,標準化されたquality of life(QOL)尺度を用いて,全国的な横断的調査を施行した.研究参加群(解析対象)442例と研究不参加群(非解析対象)1186例の背景因子を比較したところ,解析対象群で同種骨髄/臍帯血例がやや多く自家末梢血例が少ない傾向があり,解析対象群では最近の移植例が多く,骨髄非破壊的前処置とGVHD予防としてタクロリムスが多い傾向が見られた.しかし解析対象群と非解析対象群において,性別や移植時年齢分布はほぼ同等で,移植対象原疾患の内訳にも差は認められず,生着不全や急性・慢性GVHDに関しても頻度・程度共に両群で有意差を認めなかったことから,本研究参加群の解析によって本邦の小児HSCT長期生存例のQOLを知ることが可能である.(UMIN9546)

10.7889/hct-18-002 article JA Journal of Hematopoietic Cell Transplantation 2018-01-01

There is no established treatment for patients with acute promyelocytic leukemia (APL) refractory to targeted therapies all-trans retinoic acid (ATRA) and/or arsenic trioxide (ATO). We report here a case of an 8-month-old girl APL who failed standard ATRA-combined chemotherapy. Although molecular remission was achieved after introducing ATRA/ATO combination therapy, relapse occurred during the ATO consolidation courses. Subsequent rapidly administering 2 doses gemtuzumab ozogamicin. She...

10.1097/mph.0000000000002404 article EN Journal of Pediatric Hematology/Oncology 2022-01-28

Long-term follow up in adulthood after childhood cancer therapy is particularly important because of the risk late effects, and information on rate continuing hospital visits by survivors (CCS) also for planning studies effects.The ("long-term up") 1,252 cases registered multicenter Japan Association Childhood Leukemia Study Acute Lymphoblastic (JACLS ALL-02) was investigated using data from its electronic capture (EDC) system, including case number, date diagnosis, completion, birth, sex,...

10.1111/ped.13528 article EN Pediatrics International 2018-02-07

Transient hyperphosphatasemia (TH) is defined as marked elevation of serum alkaline phosphatase (ALP), predominantly its bone or liver isoform. It a rare condition and usually detected on laboratory examination in patients without any clinical symptoms. In typical with TH, ALP spontaneously normalizes, but no apparent cause TH has been identified. Some drugs are suspected triggers clear evidence their association shown to date. We herein report three cases pediatric patients. Two were...

10.1111/ped.12923 article EN Pediatrics International 2016-05-01
Sayuri Yokota Koji Amano Shunsuke Oyamada Hiroto Ishiki Isseki Maeda and 95 more Tomofumi Miura Yutaka Hatano Yu Uneno Tetsuo Hori Yosuke Matsuda Hiroyuki Kohara Kozue Suzuki Tatsuya Morita Masanori Mori Satoshi Inoue Naosuke Yokomichi Kengo Imai Hiroaki Tsukuura Toshihiro Yamauchi Akemi Shirado Naito Akira Yoshioka Shuji Hiramoto Ayako Kikuchi Keiko Tanaka Tina Kamei Yukari Azuma Teruaki Uno Jiro Miyamoto Hirofumi Katayama Hideyuki Kashiwagi Eri Matsumoto Kiyofumi Oya Takeya Yamaguchi Tomonao Okamura Hoshu Hashimoto Shunsuke Kosugi Nao Ikuta Yaichiro Matsumoto Takashi Ohmori Takehiro Nakai Takashi Ikee Yuto Unoki Kazuki Kitade Shu Koito Nanao Ishibashi Masaya Ehara Kosuke Kuwahara Shohei Ueno Shunsuke Nakashima Yuta Ishiyama Akihiro Sakashita Ryo Matsunuma Hana Takatsu Takashi Yamaguchi Satoko Ito Toru Terabayashi Jun Nakagawa Tetsuya Yamagiwa Akira Inoue Takuhiro Yamaguchi Mitsunori Miyashita Saran Yoshida Yusuke Hiratsuka Keita Tagami Hiroaki Watanabe Takuya Odagiri Tetsuya Ito Masayuki Ikenaga Keiji Shimizu Akira Hayakawa Rena Kamura Takeru Okoshi Tomohiro Nishi Kazuhiro Kosugi Yasuhiro Shibata Takayuki Hisanaga Takahiro Higashibata Ritsuko Yabuki Shingo Hagiwara Miho Shimokawa Satoshi Miyaké Junko Nozato Specially Appointed Tetsuji Iriyama Keisuke Kaneishi Mika Baba Yoshihisa Matsumoto Ayumi Okizaki Yuki Watanabe Yuko Uehara Eriko Satomi Kaoru Nishijima Junichi Shimoinaba Ryoichi Nakahori Takeshi Hirohashi Jun Hamano Natsuki Kawashima Takashi Kawaguchi Megumi Uchida Ko Sato

<h2>Summary</h2><h3>Background</h3> The benefits of artificial nutrition and hydration in patients with head neck cancer esophageal the late stage remain unknown. We performed a secondary analysis cohort study to investigate effects enteral tube feeding (ETF) parenteral (PNH) on survival this population. <h3>Methods</h3> Patients admitted palliative care units were included. Information primary nutritional administration routes during first week admission data averaged calorie sufficiency...

10.1016/j.nutos.2021.11.008 article EN cc-by-nc-nd Clinical Nutrition Open Science 2021-12-03

The outcomes of osteosarcoma with poor prognostic factors, such as responders, metastatic disease at diagnosis, and relapsed or refractory disease, are poor. We reviewed the clinical records patients diagnosed our institute between 2004 2018 who received high-dose chemotherapy followed by autologous stem cell transplantation (ASCT) in institute. Ten responder, status, diagnosis ASCT. Four underwent ASCT conditioning regimen consisted thiotepa melphalan (MEL). Five intravenous busulfan (BU)...

10.1080/08880018.2020.1729906 article EN Pediatric Hematology and Oncology 2020-03-10
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