A5100451585- Cancer-related gene regulation
- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- Cardiovascular and Diving-Related Complications
- PARP inhibition in cancer therapy
- RNA Interference and Gene Delivery
- Immunotherapy and Immune Responses
- Radiopharmaceutical Chemistry and Applications
- ATP Synthase and ATPases Research
- Virus-based gene therapy research
- Ovarian cancer diagnosis and treatment
- MicroRNA in disease regulation
- Mesenchymal stem cell research
- Neonatal Respiratory Health Research
- Immune cells in cancer
- Lung Cancer Research Studies
- Vascular Malformations and Hemangiomas
- Trauma Management and Diagnosis
- Immune Response and Inflammation
- Aortic Disease and Treatment Approaches
- Medical Imaging and Pathology Studies
- Phytochemical Studies and Bioactivities
- Cytokine Signaling Pathways and Interactions
- Berberine and alkaloids research
- IL-33, ST2, and ILC Pathways
Harbin Medical University
2022-2023
Third Affiliated Hospital of Harbin Medical University
2022-2023
Yichang Central People's Hospital
2018-2022
Changhai Hospital
2007-2013
Second Military Medical University
2007-2013
Previous studies proved that bone marrow-derived mesenchymal stem cells (BMSCs) could improve a variety of immune-mediated disease by its immunomodulatory properties. In this study, we investigated the effect on airway remodeling and inflammation administrating BMSCs in chronic asthmatic mice. Forty-eight female BALB/c mice were randomly distributed into PBS group, treatment control group. The levels cytokine immunoglobulin serum bronchoalveolar lavage fluid detected enzyme-linked...
Abstract Mesenchymal stem cells attenuate the severity of lung injury due to their immunomodulatory properties. The effect bone marrow‐derived mesenchymal on asthma is seldom reported. We have examined BMSCs airway inflammation in asthma. Forty female BALB/c mice were equally randomised into PBS group, treatment control group and asthmatic group. Reactivity acetylcholine was measured by barometric plethysmography. Cytokine profiles bronchoalveolar lavage fluid serum determined enzyme‐linked...
Abstract Background So far, few have concerned miR-497-5p in lung squamous cell carcinoma (LUSC). Methods MiR-497-5p expression LUSC was measured by qRT-PCR. Its impacts on tumor-related behaviors were investigated CCK8 assay, scratch healing flow cytometry and Transwell invasion methods. In addition, interaction between CDCA4 also elucidated through rescue experiment, western blot, dual-luciferase, bioinformatics analysis. Results Low level of confirmed tissue cells. Overexpressed markedly...
Studies have indicated that AGR2 is crucial in many cancers. However, its methylation level lung adenocarcinoma (LUAD) rarely known. Hence, the effect of on LUAD was explored study.qRT-PCR adopted to detect expression cells and normal cells. Methylation-specific PCR (MSP) used promoter region different cell lines. MTT, Transwell wound healing assays were verify progression each transfection group.The significantly up-regulated relative Moreover, inversely modulated by DNA methylation,...
The prevalence of patent foramen ovale (PFO) is 20-25% among adults. role right-to-left shunting through the PFO in systemic hypoxemia remains poorly understood. Right-to-left can occur either due to elevated right atrial pressure (pressure-driven) or directed venous flow toward (flow-driven). Herein, we report a rare case flow-driven via patient with traumatic tricuspid regurgitation. A 45-year-old Chinese woman was admitted progressive dyspnea for 3 years, presenting cyanosis and digital...
In randomized phase 3 NORA trial (NCT03705156), niraparib maintenance therapy with an individualized starting dose (ISD) significantly improved PFS (PFS; primary endpoint) and provided a favorable OS (OS; secondary trend versus placebo, in patients platinum-sensitive recurrent ovarian cancer (PSROC). Evaluating controlled trials can often be confounded by bias introduced subsequent therapy. Considerable numbers of placebo arm received PARPi This updated analysis aims to describe the...
Objective: This study intended to unravel the relationship of EVI2B expression with lung adenocarcinoma (LUAD). Methods: TIMER1.0, Gene Expression Profiling Interactive Analysis and Human Protein Atlas databases, as well University Alabama at Birmingham Cancer website, were used analyze its clinical features. The between survival curve analysis prognosis was analyzed. role in LUAD verified by wet experiments. Results:EVI2B markedly downregulated LUAD. There a Low level substantially...
Abstract Pulmonary Sequestration (PS) is a rare congenital lung disease in which the fetal part of tissue separates from main pulmonary tissue, separate development form does not have function and accepts systemic arterial blood supply cystic masses, clinically mostly asymptomatic. However, due to risk infection cancer, surgical removal current still preferred treatment for disease. Thoracoscopic direct thoracotomy are both feasible options. Despite fact isolation vessel this case was...
The prevalence of patent foramen ovale (PFO) is 20–25% among adults. role right-to-left shunting through the PFO in systemic hypoxemia remains poorly understood. Right-to-left can occur either due to elevated right atrial pressure (pressure-driven) or directed venous flow toward (flow-driven). Herein, we report a rare case flow-driven via patient with traumatic tricuspid regurgitation. A 45-year-old Chinese woman was admitted progressive dyspnea for 3 years, presenting cyanosis and digital...