A5101766074- Glycosylation and Glycoproteins Research
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Electron and X-Ray Spectroscopy Techniques
- Cancer, Hypoxia, and Metabolism
- Hepatocellular Carcinoma Treatment and Prognosis
- Hepatitis B Virus Studies
- Liver Disease Diagnosis and Treatment
- Proteoglycans and glycosaminoglycans research
- Liver Disease and Transplantation
- GDF15 and Related Biomarkers
- Diet and metabolism studies
- Atherosclerosis and Cardiovascular Diseases
- Diabetes and associated disorders
- Bacterial Identification and Susceptibility Testing
- Digital Holography and Microscopy
- Ion-surface interactions and analysis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Advanced Electron Microscopy Techniques and Applications
- COVID-19 diagnosis using AI
- Fatty Acid Research and Health
- Microscopic Colitis
- Non-Destructive Testing Techniques
- Advanced biosensing and bioanalysis techniques
- Cardiac Fibrosis and Remodeling
Shanghai Changzheng Hospital
2018-2024
Shanghai Ninth People's Hospital
2024
Shanghai Jiao Tong University
2024
Soochow University
2023
Second Military Medical University
2016-2022
Beijing Center for Disease Prevention and Control
2020
Torch Technologies (United States)
2008
Background/Aims: Neural precursor cell-expressed developmentally down-regulated gene 4 (NEDD4) plays an important role in tumor cell growth, yet its hepatocellular carcinoma (HCC) remains unclear. This study is to establish NEDD4 as a prognostic biomarker by which the survival of HCC patients can be predicted and reveal growth. Methods: The expression 219 specimens was assessed immunohistochemistry. Postoperative overall time recurrence were evaluated univariate multivariate analyses. roles...
Abstract Background Most of the biological functions circular RNAs (circRNAs) and potential underlying mechanisms in hepatocellular carcinoma (HCC) have not yet been discovered. Methods In this study, using circRNA expression data from HCC tumor tissues adjacent Gene Expression Omnibus database, we identified out differentially expressed circRNAs verified them by qRT-PCT. Functional experiments were performed to evaluate effects circFAM13B vitro vivo. Results We found that was most...
Immune disorders are key heart failure (HF) triggers, but little is known about whether the status of immunity affects incidence HF. To explore this, we used blood cell counts and derived ratios to investigate association between markers HF incidence.
The aim of this study was to investigate the prognostic value dicarbonyl/L-xylulose reductase (DCXR) in human hepatocellular carcinoma (HCC). Immunohistochemistry and tissue microarrays were used evaluate DCXR protein expression levels. Image-Pro Plus calculate integral optic density (IOD) each sample, which represented level DCXR. proteins found be significantly lower HCC tumor tissues (P < 0.0001) according immunohistochemical analysis levels 74 paired peritumoral non-cancer tissues....
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Omicron variant infection has become widespread in China as a result of the alterations epidemic control and prevention policies. We identified clinical characteristics lung computed tomography (CT) imaging patients infected during early stage BA.5 wave Shanghai to provide guide diagnosis, treatment, prognosis infection.
Activation of chronic hepatitis B virus (HBV) infection is an important cause acute-on-chronic liver failure (ACLF). However, the effect HBV-ACLF episode on hepatocellular carcinoma (HCC) occurrence remains largely unknown. A total 769 patients and 2114 HBV-related disease (HBV-CLD) diagnosed between August 1998 December 2011 were enrolled in this prospective cohort study. Of HBV-CLD patients, 380 received lifetime antiviral treatment with nucleos(t)ide analogues. Propensity score matching...
We present a case of 43-year-old man with advanced hepatocellular carcinoma (HCC) portal vein tumour thrombus. Initially, transcatheter arterial chemoembolization (TACE) was performed. Although alpha-fetoprotein (AFP) levels decreased, circulating DNA (ctDNA) showed an upward trend, and abdominal magnetic resonance imaging (MRI) that tumours in the had increased. Based on ctDNA profiling, apatinib anti-programmed cell death protein 1 (anti-PD-1) antibodies were sequentially administered....
Lensless Coaxial Digital Holographic Imaging (LCDHI) has great advantages of wide-field, high resolution and non-destructive measurement. By removing traditional lenses utilizing a coaxial optical path, the lens-aberration can be avoided, imaging process is greatly simplified, which one powerful tools for observing micro components biological cells. With help an open-source hardware deep learning technology, simple portable experimental device based on principle lensless digital holography...
Abstract Background: Recently, patients with COVID-19 who showed persistently positive SARS-CoV-2 nucleic acid test results despite resolved clinical symptoms have attracted a lot of attention. We report the case patient mild coronavirus disease (COVID-19), achieved recovery but until Day 92 after onset. Case presentation: The is 50-year-old man (COVID-19). He was quarantined for 105 days. Of these, inpatient quarantine lasted 75 When were negative 3 consecutive days, discharged at During...
Abstract Aims The cycle threshold (Ct) value for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleic acid detection is important because of the criteria quarantine management, including release from it, which are defined in Guidelines on Novel Coronavirus-Infected Pneumonia Diagnosis and Treatment (Provisional 9th Edition, China). As this also currently relevant recent SARS-CoV-2 epidemic Shanghai, we discuss its problems. We focus gene fragments sample types involved their...