A5039489603- Antibiotics Pharmacokinetics and Efficacy
- Neuroscience and Neuropharmacology Research
- Risk Perception and Management
- Pharmaceutical studies and practices
- Drug-Induced Adverse Reactions
- Ethics in Clinical Research
- Esophageal and GI Pathology
- Sarcoidosis and Beryllium Toxicity Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Cardiac and Coronary Surgery Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Aortic Disease and Treatment Approaches
- Congenital Heart Disease Studies
- Health Systems, Economic Evaluations, Quality of Life
- Homotopy and Cohomology in Algebraic Topology
- Blood disorders and treatments
- Neonatal Health and Biochemistry
- Olfactory and Sensory Function Studies
- Ion channel regulation and function
- Rheumatoid Arthritis Research and Therapies
- Disaster Response and Management
- Biochemical Analysis and Sensing Techniques
- Tracheal and airway disorders
- Ethics in medical practice
- Helicobacter pylori-related gastroenterology studies
Meikai University
2021-2024
National Institute of Public Health
2013-2022
Osaka University
2008-2022
IRYO Sosei University
2021-2022
Teikyo Heisei University
2018-2022
Leiden University Medical Center
2022
Saiseikai Ibaraki Hospital
2021-2022
The University of Tokyo
2004-2021
Iwate Prefectural Central Hospital
2010-2021
Chiba University
2019
Metabolic syndrome comprises a cluster of metabolic abnormalities leading to insulin resistance and atherosclerosis, Helicobacter pylori is thought be contributing factor.We examined the association between H. infection in large Japanese population.Consecutive asymptomatic subjects that underwent complete medical survey our institute April 2006 March 2007 were recruited, total 5,488 men 1,906 women cross-sectionally studied. The serostatus with traditional atherosclerosis risk factors was...
Intensive cardiac management such as pharmacological intervention for ductal patency (indomethacin and/or mefenamic acid closure and prostaglandin E1 maintenance) palliative or corrective surgery is a standard treatment congenital heart defects. However, whether it would be option children with trisomy 13 18 syndrome controversial because the efficacy on survival in patients these trisomies has not been evaluated. We retrospectively reviewed 31 consecutive neonates admitted to our neonatal...
Continuous-wave Doppler echocardiography was used to examine the aortic regurgitant flow velocity pattern in 32 patients with regurgitation (AR) and 10 without AR. The patterns, characterized by a rapid rise immediately after closure of valve, high peak velocity, gradual deceleration until next valve opening, were successfully obtained 30 AR (sensitivity 94%, specificity 100%). decline greater severe AR; thus, slope (deceleration) time half (half-time index) measured from pattern. became...
Abstract Background: Helicobacter pylori infection has been shown to contribute atherosclerosis and cardiovascular diseases. Insulin resistance is the pathophysiologic background of clinical features We examined association between H. insulin in a large Japanese population. Materials Methods: Fifteen hundred ninety‐eight consecutive asymptomatic subjects that underwent complete medical survey our institute May 2007 July 2008 were recruited. Cases under medication for hypertension,...
OBJECTIVES: The effect of alcohol consumption on the liver is controversial. Recent reports have suggested that moderate decreases prevalence elevated alanine aminotransferase levels. role in development fatty (FL), however, has not been studied definitively. aim this study was to examine association between and FL a large Japanese population. METHODS: A total 7,431 asymptomatic male subjects who underwent complete medical survey our institute May 2007 July 2008 were recruited. Cases...
Vitamin D has been shown to have anti-angiogenic properties and play a protective role in several types of cancer, including breast, prostate cutaneous melanoma. Similarly, vitamin levels be for risk number conditions, cardiovascular disease chronic kidney disease, as well numerous autoimmune disorders such multiple sclerosis, inflammatory bowel diseases type 1 diabetes mellitus. A study performed by Parekh et al. was the first suggest age-related macular degeneration (AMD) showed...
Background: We estimated the prevalence and incidence of chronic intestinal pseudo-obstruction (CIPO) in Japan, investigated patterns hospital visits among those with CIPO, examined present knowledge CIPO medical professionals.Methods: A self-administered questionnaire survey was distributed to targeted hospitals throughout which were selected using stratified random sampling. The asked about number patients receiving treatment for frequency their visits, overall clinical...
Peristaltic flow due to the transverse deflections of walls curved channel is investigated when inertial effect negligibly small and wavelength sufficiently long compared with width. Theoretical results are presented for stream function, velocity pressure. criteria reflux trapping obtained. The pressure-flow characteristic found be linear, its slope slightly increases an increasing curvature. Reflux near outer wall stronger than inner wall. trapped bolus fluid comprises 2 asymmetrical parts...
The acute respiratory distress syndrome (ARDS) is an extreme form of lung injury characterised by disruption to the alveolar epithelium. KL-6 a mucin-like glycoprotein expressed on type II pneumocytes. Circulating levels have diagnostic and prognostic significance in number interstitial diseases, when elevated are thought indicate epithelial lining. In this study, authors sought determine whether plasma were patients with ARDS these associated aetiology, disease severity, outcome or...
Sarcoidosis and Crohn's disease are heterogeneous systemic diseases characterised by granulomatous inflammation. Caspase recruitment domain (CARD)15 is a major susceptibility gene for disease, specifically ileal fibrostenotic subtypes. The C-C chemokine receptor (CCR)5 has been associated with both parenchymal pulmonary sarcoidosis perianal disease. This study explored associations between CARD15 polymorphisms, CCR5 haplotype distinct 185 Caucasian patients were genotyped polymorphisms....
This study sought to characterize the plasma metabolite profiling of patients with major depressive disorder (MDD).Psychiatric assessments were made Structured Clinical Interview for DSM-IV Axis I Disorders. In exploratory cohort, profiles 34 MDD and 31 mentally healthy controls compared using capillary electrophoresis-mass spectrometry. Among candidate metabolites, we focused on a showing largest difference. The absolute concentrations measured in two cohorts from psychiatric primary care...
The purpose of the present study was to investigate effects vagal blocker atropine on fractal nature human heart rate variability (HRV) at rest. Approximately 10-min segments beat-to-beat heartbeat intervals, i.e., HRV, 10 normal subjects and 11 cardiac disease patients were measured before after intravenous injection 0.5-0.75 mg sulfate. HRV data analyzed by coarse graining spectral analysis (Y. Yamamoto R. L. Hughson, Physica 68D: 250-264, 1993) break down their total power into harmonic...
Abstract Sarcoidosis is a heterogeneous disorder, both phenotypically and genetically. Two independent studies have recently shown that functional polymorphism within butyrophilin‐like 2 ( BTNL2 ) gene predisposes to sarcoidosis independently of the human leukocyte antigen (HLA)‐DRB1 alleles. However, in studies, data analysis was not stratified by Löfgren’s syndrome, clinically genetically distinct subset. , potentially encoding an immune coreceptor, adjacent linkage disequilibrium (LD)...