Da Huo

ORCID: 0000-0003-0806-8117
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About
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Research Areas
  • Viral Infections and Immunology Research
  • Animal Disease Management and Epidemiology
  • Viral gastroenteritis research and epidemiology
  • COVID-19 epidemiological studies
  • Respiratory viral infections research
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Color Science and Applications
  • Textile materials and evaluations
  • Viral Infections and Vectors
  • Color perception and design
  • Tissue Engineering and Regenerative Medicine
  • T-cell and Retrovirus Studies
  • Research Data Management Practices
  • Radiomics and Machine Learning in Medical Imaging
  • Semantic Web and Ontologies
  • Whipple's Disease and Interleukins
  • COVID-19 and Mental Health
  • Virology and Viral Diseases
  • Auction Theory and Applications
  • Obesity, Physical Activity, Diet
  • Influenza Virus Research Studies
  • Health disparities and outcomes
  • Nutritional Studies and Diet
  • Animal Virus Infections Studies
  • Electrospun Nanofibers in Biomedical Applications

General Hospital of Shenyang Military Region
2025

Huazhong University of Science and Technology
2025

Capital Medical University
2000-2024

Beijing Center for Disease Prevention and Control
2014-2024

Wuhan Textile University
2022

Army Medical University
2016-2021

Weifang People's Hospital
2021

Shanghai Jiao Tong University
2020-2021

Wuyi University
2019

Xi'an Jiaotong University
2018-2019

Introduction Transmission of COVID-19 within families and close contacts accounts for the majority epidemic growth. Community mask wearing, hand washing social distancing are thought to be effective but there is little evidence inform or support community members on risk reduction families. Methods A retrospective cohort study 335 people in 124 with at least one laboratory confirmed case was conducted from 28 February 27 March 2020, Beijing, China. The outcome interest secondary transmission...

10.1136/bmjgh-2020-002794 article EN cc-by-nc BMJ Global Health 2020-05-01

Etiology surveillance of Hand Foot and Mouth disease (HFMD) in Beijing showed that Coxsackievirus A6 (CVA6) became the major pathogen HFMD 2013 2015. In order to understand epidemiological characteristics clinical manifestations CVA6-associated HFMD, a comparison study among CVA6-, EV71- (Enterovirus 71), CVA16- (Coxsackievirus A16) associated was performed. Epidemiological CVA16-associated mild or severe cases were compared from VP1 gene CVA6 EV71 cases, sequenced, aligned, with strains...

10.3389/fmicb.2016.00391 article EN cc-by Frontiers in Microbiology 2016-03-30

Rotavirus is a leading cause of severe diarrheal disease, and one the common causes death in children aged under five years old. The dominant epidemic strains may change different same area. In order to provide evidence for rotavirus control inform vaccine development, we analyzed epidemiological patterns genetic characteristics Beijing during 2011–2016. Stool specimens outpatient old were collected from three children’s hospitals on weekly basis. Group A antigens detected using...

10.1186/s12879-018-3411-3 article EN cc-by BMC Infectious Diseases 2018-10-03

This study aimed to evaluate the public health countermeasures against coronavirus disease 2019 (COVID-19) that are important for organizing mass gathering events (MGEs) during a pandemic and identify practices suitable application at future MGEs. analyzed data from Beijing 2022 Olympic Winter Games. The aforementioned analysis was conducted viewpoints of overseas stakeholders Chinese residents. comprehensive set established prevent transmission COVID-19 comprised bubble strategy,...

10.3389/fpubh.2023.1068023 article EN cc-by Frontiers in Public Health 2023-02-06

In recent years, interventional surgery has become a treatment for ischemic stroke due to its low risk of injury. However, the occurrence restenosis hinders long-term effectiveness and safety stent implantation. At present, drug-eluting stents mainly prevent stenosis by inhibiting proliferation smooth muscle cells (SMCs). these drugs cause damage endothelial (ECs), timely re endothelialization blood vessels, increase late thrombosis restenosis. EPS-15-interacting protein 1 (Epsin1)- 2...

10.1371/journal.pone.0318019 article EN cc-by PLoS ONE 2025-03-25

Abstract Multimodal sensory integration is vital for the evolution of artificial intelligence, yet current approaches often rely on physically connecting distinct sensing units (such as visual and tactile devices) through external circuits, leading to data transmission delays information loss. Here, a groundbreaking paradigm demonstrated integrating visual‐tactile fusion perception in one device with single functional material. This achieved by developing an unprecedented 2D...

10.1002/adma.202500049 article EN Advanced Materials 2025-04-07

Introduction: Enterovirus A71(EV-A71)-associated hand, foot, and mouth disease (HFMD) has been reported worldwide, poses a particularly heavy burden on patients, families, society in China. Three Chinese companies have licensed inactivated EV-A71 vaccines, all of which demonstrated good efficacy for preventing EV-A71-associated clinical trials. However, real-world performance vaccine not evaluated.Methods: We used test-negative design case-control study to estimate effectiveness (VE) against...

10.1080/21645515.2019.1581539 article EN cc-by-nc-nd Human Vaccines & Immunotherapeutics 2019-03-20

In e-commerce advertising, it is crucial to jointly consider various performance metrics, e.g., user experience, advertiser utility, and platform revenue. Traditional auction mechanisms, such as GSP VCG auctions, can be suboptimal due their fixed allocation rules optimize a single metric (e.g., revenue or social welfare). Recently, data-driven learned directly from outcomes multiple have attracted increasing research interests. However, the procedure of mechanisms involves discrete...

10.1145/3447548.3467103 article EN 2021-08-12

<abstract abstract-type="Summary"> <sec> <b>What is already known about this topic?</b> Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to evolve, the clinical manifestations resulting from different SARS-CoV-2 variants may demonstrate significant variation. </sec><sec> added by report?</b> We conducted a comparative analysis of features associated with Omicron subvariants BF.7.14 and BA.5.2.48 infections. The results our study indicate that there are no substantial...

10.46234/ccdcw2023.096 article EN China CDC Weekly 2023-01-01

Norovirus (NoV) is a leading cause of sporadic cases and outbreaks acute gastroenteritis (AGE). Increased NoV activity was observed in Beijing, China during winter 2014–2015; therefore, we examined the epidemiological patterns genetic characteristics outbreaks. The weekly number infectious diarrhea reported by all hospitals Beijing analyzed through information system for disease control prevention. Fecal specimens were collected from outpatients with AGE, GI GII NoVs detected using real time...

10.1186/s12879-015-1315-z article EN cc-by BMC Infectious Diseases 2015-12-01

Objective: To probe the spatiotemporal patterns of incidence scarlet fever in Beijing, China, from 2005 to 2014. Methods: A analysis was conducted at district/county level Beijing region based on reported cases during study period. Moran’s autocorrelation coefficient used examine spatial fever, whereas Getis-Ord Gi* statistic determine hotspot fever. Likewise, space-time scan detect clusters, including relative risk across all settings. Results: total 26,860 were period (2005–2014). The...

10.3390/ijerph13010131 article EN International Journal of Environmental Research and Public Health 2016-01-15

Coxsackievirus A6 (CVA6) is one of the major agents to cause hand, foot and mouth disease (HFMD) outbreaks globally. The objective this study investigate epidemiologic clinical manifestations CVA6 outbreak, thus guide diagnosis treatment disease, as well prevention. An HFMD outbreak in a kindergarten was reported Shijingshan District Center for Disease Control Prevention (SCDC) on November 2, 2015 Beijing, China. Epidemiological investigation conducted. We performed nine-week follow-up...

10.1186/s12887-018-1253-1 article EN cc-by BMC Pediatrics 2018-08-21

Summary Background SARS-CoV-2 has been a global pandemic, but the emergence of asymptomatic patients caused difficulties in prevention epidemic. Therefore, it is significant to understand epidemiological characteristics with infection. Methods In this single-center, retrospective and observational study, we collected data from 167 infection treated Chongqing Public Health Medical Center (Chongqing, China) January March 2020. The variable these were analyzed. Findings 82.04% infected had...

10.1101/2020.03.16.20037259 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-03-23

Cell therapy has been a promising strategy for cardiac repair after myocardial infarction (MI), but poor ischemic environment and low cell delivery efficiency remain significant challenges. The spleen serves as hematopoietic stem niche secretes cardioprotective factors MI, it is unclear whether could be used human pluripotent (hiPSC) cultivation provide proper microenvironment grafts against the environment. Herein, we developed splenic extracellular matrix derived thermoresponsive hydrogel...

10.1016/j.bioactmat.2021.04.010 article EN cc-by-nc-nd Bioactive Materials 2021-05-03

Objective To examine the associations of combined lifestyle factors and physical conditions with cerebrovascular diseases (CBVD) mortality, after accounting for competing risk events, including death from cardiovascular diseases, cancers other diseases. Methods Data on 2010 subjects aged over 55 years were finally analyzed using models. All interviewed by Beijing Longitudinal Study Aging (BLSA), in China, between 1 January 1992 30 August 2009. Results Elderly females at a lower CBVD than...

10.1371/journal.pone.0087884 article EN cc-by PLoS ONE 2014-02-04

Abstract Coxsackievirus A16 (CV‐A16) is a significant etiologic agent of hand, foot, and mouth disease (HFMD) herpangina (HA), with the capacity to progress severe complications, including encephalitis, aseptic meningitis, acute flaccid paralysis, myocarditis, other critical conditions. Beijing's epidemiological surveillance system, established in 2008, encompasses 29 hospitals 16 district control centers. From 2019 2021, circulation CV‐A16 was characterized by co‐circulation B1a B1b clades....

10.1002/jmv.29796 article EN Journal of Medical Virology 2024-07-01

Abstract Aortic dissection is one of the most clinical-challenging and life-threatening cardiovascular diseases associated with high morbidity mortality. requires fast diagnosis timely therapy. Any delay or misdiagnosis can cause severe consequence to aortic patients even higher To better help physicians identify potential within scope all misdiagnosed patients, this paper describes a method which developed data mining methods for patient classification prediction in phase early diagnosis....

10.1038/s41598-019-39066-9 article EN cc-by Scientific Reports 2019-02-25

We analyzed surveillance data for 2 sentinel hospitals to estimate the influenza-associated severe acute respiratory infection hospitalization rate in Beijing, China. The was 39 and 37 per 100,000 persons during 2014-15 2015-16 influenza seasons, respectively. Rates were highest children <5 years of age.

10.3201/eid2411.171410 article EN cc-by Emerging infectious diseases 2018-09-20

5585 Background: There is no effective treatment for UCA/CS pts who have progressed on platinum-taxane therapy. Increased levels of VEGF are frequently seen in UCA and CS, antiangiogenic therapy has shown activity a mouse model UCA. Sorafenib multitargeted kinase inhibitor with that approved use renal hepatocellular carcinoma. Methods: We initiated multi-center phase II trial SOR advanced/recurrent (arm A) or CS B) 0–1 prior chemotherapy regimens. PS 0–2 measurable disease were required. The...

10.1200/jco.2008.26.15_suppl.5585 article EN Journal of Clinical Oncology 2008-05-20
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