- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Management of metastatic bone disease
- Spinal Dysraphism and Malformations
- Spinal Cord Injury Research
- Nerve Injury and Rehabilitation
- Cervical and Thoracic Myelopathy
- Musculoskeletal pain and rehabilitation
- Head and Neck Surgical Oncology
- Soft tissue tumors and treatment
- Meningioma and schwannoma management
- Bone Tumor Diagnosis and Treatments
- Infectious Diseases and Tuberculosis
- Peripheral Nerve Disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Venous Thromboembolism Diagnosis and Management
- Intracranial Aneurysms: Treatment and Complications
- Ophthalmology and Eye Disorders
- Scoliosis diagnosis and treatment
- Pelvic and Acetabular Injuries
- Neurosurgical Procedures and Complications
- Orthopedic Surgery and Rehabilitation
- Diagnosis and Treatment of Venous Diseases
- Spinal Hematomas and Complications
- Neuroscience and Neural Engineering
Icahn School of Medicine at Mount Sinai
2012-2025
NeuroSpine Institute
2019-2023
Mount Sinai Hospital
2018-2023
Mount Sinai Health System
2017-2023
Mount Sinai Hospital
2020-2022
Neurological Surgery
2017
University of Miami
2017
Health Net
2017
University of Calgary
2017
University of Maryland, Baltimore
2017
Decreased cerebral blood flow (CBF) and ischemia occurring immediately after subarachnoid hemorrhage (SAH) may be caused by acute microvascular constriction. However, CBF can also influenced changes in intracranial pressure (ICP) perfusion (CPP). The goal of these experiments was to assess the significance vasoconstriction SAH its relationship CBF, ICP, CPP, extracellular glutamate concentrations.Three were performed using endovascular filament technique produce SAH. In first experiment, CPP...
Human central nervous system stem cells (HuCNS-SC) are multipotent adult with successful engraftment, migration, and region-appropriate differentiation after spinal cord injury (SCI).To present data on the surgical safety profile feasibility of multiple intramedullary perilesional injections HuCNS-SC SCI.Intramedullary free-hand (manual) transplantation was performed in subjects thoracic (n = 12) cervical 17) complete sensory incomplete chronic traumatic cell needle times cohort (20 M...
Introduction The volume of cervical spine procedures continues to grow. Plastic and reconstructive surgeons (PRSs) commonly address complex wound-related issues in such cases. present study investigates whether routine PRS closure spinal wounds improves outcomes compared with those performed without. Methods Data patients operated on for by the senior author (P.J.T.) between January 2016 June 2023 were analyzed. Only posterior surgical approaches included. Demographics, medical status,...
Abstract OBJECTIVE Our goals were to study the normal histological features of jugular foramen, compare them with histopathological glomus tumors involving temporal bone, and thus provide insight into surgical management these respect cranial nerve function. METHODS Ten foramen blocks obtained from five human cadavers after removal brain. Microscopic studies performed, particular attention fibrous or bony compartmentalization relationships caudal nerves bulb/jugular vein internal carotid...
We present the Jenkins classification for Bertolotti syndrome or symptomatic lumbosacral transitional vertebra (LSTV) and compare this with existing Castellvi patients presenting treatment.
Background Advancements in radiological imaging and diagnostic criteria enable doctors to more accurately identify lumbosacral transitional vertebrae (LSTV) their association with back L5 distribution leg pain. It is considered the most common congenital anomaly of spine an incidence between 4 35%,3 although many practitioners describe 10 12% overall incidence. LSTVs include sacralization vertebral body lumbarization S1 segment while demonstrating varying morphology, ranging from broadened...
AIS: American Spinal Injury Association Impairment Scale MRI: magnetic resonance imaging PLGA-PLL: Poly-lactic-co-glycolic acid-Poly-L-lysine SCI: spinal cord injury Traumatic (SCI) can produce a sudden and devastating impact on quality of life due to severe motor, sensory, autonomic dysfunction, including bowel, bladder, sexual impairment. The adverse consequences traumatic SCI result from well-described pathological process involving primary secondary mechanisms.1,2 follows mechanical...
Thoracic dorsal arachnoid webs are intradural membranes that may cause obstruction of cerebrospinal fluid flow and spinal cord compression. Although well recognized, they rare there is a paucity long-term data on their natural history prognosis. We reviewed radiographic features, surgical indications, pathologic specimens patients diagnosed with focal thoracic webs.
Symptomatic multilevel cervical myelopathy is often addressed using posterior decompression two-dimensional fluoroscopy. Intraoperative three-dimensional fluoroscopy provides more accurate information on the position of instrumentation to prevent screw-related complications.We documented incidence hardware-related complications and evaluate cost-effectiveness when intraoperative (ISO-C CT) in spine surgery.Records from 87 patients who underwent instrumented fusion for spondylosis with were...
To use a novel modified intraoperative fluoroscopic view for spinal level localization.To evaluate the safety and utility of oblique technique localization distal cervical proximal thoracic levels.Operative radiographic cervicothoracic spine using standard anterior-posterior lateral views is made difficult by its anatomic relationship to shoulder upper chest, which produce shadowing obscuring spine. Additional image degradation can be caused muscular patients or those with high body mass...
Purpose: The role of the plastic surgeon in wound management following complications from prior spinal surgeries is well established. present study evaluates closure primary surgery a large patient population. Methods: Spinal closed by single at academic hospital were reviewed. Descriptive statistics applied and outcomes this sample compared with previously published using 2-sample z tests. Results: Nine hundred twenty-eight reviewed, which 782 included. Seven fifteen operations for...
Vagus nerve stimulation (VNS) is the most widely used non-pharmacological treatment for medically intractable epilepsy and has been in clinical use over a decade. It indicated patients who are refractory to medical or experience intolerable side effects, not candidates resective surgery. VNS acute setting can both abort seizures have an prophylactic effect. This effect increases time chronic maximum at around 18 months. The evidence base supporting efficacy of strong, but its exact mechanism...
Spinal cord injury is a devastating condition with no effective treatment. The physiological processes that impede recovery include potentially detrimental immune responses and the production of reactive astrocytes. Previous work suggested radiation treatment might be beneficial in spinal injury, although method carries risk radiation-induced damage. To overcome this obstacle we used arrays parallel, synchrotron-generated X-ray microbeams (230 μm 150 gaps between them) to irradiate an...